Results 191 to 200 of about 521,930 (421)
Hypersensitivity Pneumonitis: A Comprehensive Review [PDF]
none8siHypersensitivity pneumonitis (HP), also known as extrinsic allergic alveolitis, is a complex pulmonary syndrome mediated by the immune system and caused by inhalation of a wide variety of antigens to which the individual has been previously ...
core
Application of humanized mice in the safety experiments of antibody drugs
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun+9 more
wiley +1 more source
TISSUE CULTURE STUDIES ON BACTERIAL HYPERSENSITIVITY [PDF]
Johannes K. Moen, Homer F. Swift
openalex +3 more sources
THE FACTS ABOUT PENICILLIN ALLERGY: A REVIEW
Hypersensitivity reactions are the major problem in the use of penicillins. Truepenicillin allergy is rare with the estimated frequency of anaphylaxis at 1-5 per 10 000cases of penicillin therapy.
Sanjib Bhattacharya
doaj
On the Classification of the Phenomena of Hypersensitiveness [PDF]
Arthur F. Coca, Robert A. Cooke
openalex +1 more source
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska+2 more
wiley +1 more source
Pain‐autonomic measures reveal nociceptive sensitization in complex regional pain syndrome
Abstract Background Allodynia and hyperalgesia are common signs in individuals with complex regional pain syndrome (CRPS), mainly attributed to sensitization of the nociceptive system. Appropriate diagnostic tools for the objective assessment of such hypersensitivities are still lacking, which are essential for the development of mechanism‐based ...
Paulina S. Scheuren+5 more
wiley +1 more source
A COMPARATIVE HISTOLOGIC AND IMMUNOLOGIC STUDY IN RABBITS OF INDUCED HYPERSENSITIVITY OF THE SERUM SICKNESS TYPE [PDF]
Frederick G. Germuth
openalex +1 more source
Objective A phase 2 trial tested different doses of the anti‐CD40 monoclonal antibody BI 655064 as an add‐on therapy to the standard of care in patients with class III or IV lupus nephritis (LN) with active disease. A post hoc analysis showed a potential benefit of the higher tested doses (180 and 240 mg) versus a low dose (120 mg) or placebo.
Martina Uzzo+5 more
wiley +1 more source