Results 191 to 200 of about 470,558 (290)

Serum Sickness After Cosmetic Botulinum Toxin Type A Injections. [PDF]

open access: yesAesthet Surg J Open Forum
DeLuca-Pytell D   +3 more
europepmc   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm   +7 more
wiley   +1 more source

Cannabidiol in Anorexia Nervosa: A Double‐Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota   +8 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of Cardiac Interoceptive Accuracy in Anorexia Nervosa

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Interoceptive impairments have been suggested as an etiological factor in anorexia nervosa (AN) but have not been consistently confirmed across interoceptive dimensions and bodily systems. This systematic review and meta‐analysis provides a focused investigation of cardiac interoceptive accuracy (IAcc) in AN.
Claire Gend   +2 more
wiley   +1 more source

Understanding Biologics in CRSwNP: Related Events and Insights. [PDF]

open access: yesCurr Allergy Asthma Rep
Izquierdo-Domínguez A   +4 more
europepmc   +1 more source

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo   +7 more
wiley   +1 more source

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