Results 201 to 210 of about 521,930 (421)

Migraine in university students: A systematic review and meta‐analysis

European Journal of Pain, Volume 27, Issue 1, Page 14-43, January 2023., 2023
Abstract Background Migraine is a complex, neurobiological disorder usually presenting as a unilateral, moderate to severe headache accompanied by sensory disturbances. Migraine prevalence has risen globally, affecting 14% of individuals and 16% of students and carries many negative impacts in both cohorts.
Orla Flynn, Brona M. Fullen, Catherine Blake   +2 more
wiley   +1 more source

Efficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial

Arthritis &Rheumatology, EarlyView.
Objective An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.
Robert F. Spiera, Valerie Devauchelle‐Pensec, Claire E. Owen, Federico Díaz‐González, Tsutomu Takeuchi, Edit Drescher, Jaclyn Anderson, Dilek Arikan, Ronilda D'Cunha, Julie Parmentier, Denise T. Kruzikas, Weihan Zhao, Yang Yang, Karen Stellpflug, Frank Buttgereit   +14 more
wiley   +1 more source

Transmission of Protein Hypersensitiveness from Mother to Offspring [PDF]

, 1927
Bret Ratner, Holmes C. Jackson, Helen Lee Gruehl   +2 more
openalex   +3 more sources

Observations on the Thrombocytopenia Due to Hypersensitivity to Quinidine [PDF]

, 1954
Percy Barkham, Leandro M. Tocantins
openalex   +1 more source

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, Accepted Article.
Objectives Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The Phase III MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E Wechsler, Jared Silver, Gerhard Wolff, Robert G Price, Rejina Verghis, Peter F Weller, Peter A Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

THE LYMPHOCYTIC ORIGIN OF A PLASMA FACTOR RESPONSIBLE FOR HYPERSENSITIVITY IN VITRO OF TUBERCULIN TYPE [PDF]

, 1951
Joseph M. Miller, Cutting B. Favour
openalex   +1 more source

Central sensitization: a generator of pain hypersensitivity by central neural plasticity.

Journal of Pain, 2009
Alban Latremoliere, Clifford J. Woolf
semanticscholar   +1 more source

Autistic Traits and Emotion Dysregulation in 5–11‐Year‐Old Intellectually Able Children With Autism Spectrum Condition: Mediating Role of Emotion Regulation Strategies

Autism Research, EarlyView.
ABSTRACT Emotion dysregulation (ED) is common among children with an autism spectrum condition (ASC). However, the mechanisms underlying emotion regulation strategies (ERSs) and their impacts on ED in this population remain unclear. The current study examined whether ED is directly related to autistic traits or mediated by deficits in ERSs after ...
Hsin‐Hui Lu, Angana Nandy, Hsing‐Chang Ni   +2 more
wiley   +1 more source

Lactiplantibacillus plantarum X7022 ameliorates loperamide‐induced constipation and modulates gut microbiota in mice

Food Bioengineering, Volume 1, Issue 3-4, Page 252-263, December 2022., 2022
Lactiplantibacillus plantarum X7022 is a novel strain isolated from the traditional fermented stinky tofu brine. L. plantarum X7022 could alleviate constipation by improving defection indices. L. plantarum X7022 regulated gut microbiota dysbiosis in the two different constipation models.
Xingye Chen, Guang Liu, Li Zhao, Lei Du, Jingli Xie, Dongzhi Wei   +5 more
wiley   +1 more source

Adverse events associated with monoclonal antibodies used for treatment of COVID‐19: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims This review aimed to synthesise the evidence related to the incidence of serious and non‐serious adverse events with the use of monoclonal antibodies (mAbs) among COVID‐19 patients. Methods Databases were searched from January 2020 to September 2023 for randomized clinical trials (RCTs) that used mAbs for the treatment of COVID‐19 regardless of ...
Htet Htet, Han You Kyung, Ismail Abdul Sattar Burud, Heethal Jaiprakash, Thiruselvi Subramaniam, Igor Iezhitsa, Renu Agarwal   +6 more
wiley   +1 more source