Results 201 to 210 of about 509,314 (341)

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

Clinical Pharmacology &Therapeutics, EarlyView.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Sherbet Samuels, Rebecca Racz, Mohamed A. Mohamoud, Nicholas P. Tatonetti   +6 more
wiley   +1 more source

Nitazoxanide and nonsteroidal anti-inflammatory drugs (NSAIDs): unveiling the connection in immediate hypersensitivity cross-reactions. [PDF]

Einstein (Sao Paulo)
Feodrippe ALO, Aun MV, Gagete E, Kalil J, Giavina-Bianchi P.   +4 more
europepmc   +1 more source

Treatment of iron deficiency anemia: practical considerations [PDF]

, 2015
Rampton, D, Taylor, S
core   +1 more source

Antenna Enhanced Infrared Photoinduced Force Imaging in Aqueous Environment with Super-Resolution and Hypersensitivity

, 2021
Jian Li, Jie Pang, Zhendong Yan, Junghoon Jahng, Jin Li, William Morrison, Jing Liang, Qingying Zhang, Xing‐Hua Xia   +8 more
openalex   +1 more source

Hypersensitivity Fever

International Journal of Clinical Practice, 1969
openaire   +2 more sources

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Examination of HLA-DRB1*15-linked candidate antigens in Still's disease with and without lung disease and features of drug hypersensitivity. [PDF]

J Rheumatol
Kobrin DM, Brown DG, Burbelo PD, Workman L, Rosenbaum ED, Correia Marques M, Lake C, Millwood M, Lawrence MG, Deng Z, Das S, Ombrello MJ.   +11 more
europepmc   +1 more source

A Mutation in the Intrinsivally Disordered Fragment of SK2 Channel Confers Ca2+ Hypersensitivity [PDF]

, 2018
Young Woo Nam, Saba Baskoylu, Meng Cui, Razan Orfali, Anne C. Hart, Miao Zhang   +5 more
openalex   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Case Report: Late Hypersensitivity Reaction to Hydroxyurea in a Patient With Myeloproliferative Disorder. [PDF]

Case Rep Hematol
Kahlon N, Baddam S, Kaur H, Singh P, Qureshi Z, Gowda AM.   +5 more
europepmc   +1 more source