Results 221 to 230 of about 648,308 (386)

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout   +6 more
wiley   +1 more source

Intestinal Fungal Dysbiosis Is Associated With Visceral Hypersensitivity in Patients With Irritable Bowel Syndrome and Rats.

open access: yesGastroenterology, 2017
S. Botschuijver   +13 more
semanticscholar   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Impact of carboplatin desensitization therapy on progression-free survival in gynecologic cancers. [PDF]

open access: yesGynecol Oncol Rep
Bastin N   +11 more
europepmc   +1 more source

CLINICAL INVESTIGATION CONCERNING THE EFFECTIVENESS OF A SPECIALIZED TOOTHPASTE AGAINST DENTINE HYPERSENSITIVITY

open access: hybrid, 2017
Л. Е. Леонова   +5 more
openalex   +2 more sources

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm   +7 more
wiley   +1 more source

Hypersensitivity syndrome associated with azithromycin [PDF]

open access: bronze, 2001
Raluca I. Cascaval, Danny J. Lancaster
openalex   +1 more source

Hypersensitivity Fever

open access: yesInternational Journal of Clinical Practice, 1969
openaire   +2 more sources

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