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Hypersensitivity pneumonitis [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2006
Hypersensitivity pneumonitis (HP) is a pulmonary disease with symptoms of dyspnea and cough resulting from the inhalation of an antigen to which the subject has been previously sensitized. The incidence of HP is unknown.
Cormier Yvon, Lacasse Yves
doaj   +6 more sources

Fibrotic hypersensitivity pneumonitis

open access: yesJournal of Advanced Lung Health, 2023
Hypersensitivity pneumonitis (HP), which is otherwise known as extrinsic allergic alveolitis, is a clinical syndrome characterized by diffuse interstitial involvement secondary to exposure to organic antigens.
Ravindran Chetambath, Rameesa Shanavas
doaj   +2 more sources

Chronic hypersensitivity pneumonitis

open access: yesJournal of Asthma and Allergy, 2016
Carlos AC Pereira,1 Andréa Gimenez,2 Lilian Kuranishi,2 Karin Storrer 2 1Interstitial Lung Diseases Program, 2Pulmonology Postgraduate, Federal University of São Paulo, São Paulo, Brazil Abstract: Hypersensitivity pneumonitis ...
Pereira CA   +3 more
doaj   +4 more sources

Hypersensitivity pneumonitis: Current concepts in pathogenesis, diagnosis, and treatment

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2021
Hypersensitivity pneumonitis is an immune‐mediated interstitial lung disease caused by an aberrant response to an inhaled exposure, which results in mostly T cell–mediated inflammation, granuloma formation, and fibrosis in some cases.
H. Barnes   +5 more
semanticscholar   +1 more source

Antigen identification and avoidance on outcomes in fibrotic hypersensitivity pneumonitis

open access: yesEuropean Respiratory Journal, 2022
Background Suspected causative antigens may be unidentified in 30–50% of patients with fibrotic hypersensitivity pneumonitis (f-HP). It is unclear whether antigen identification and avoidance in this setting offer any additional clinical benefit.
T. Petnak   +4 more
semanticscholar   +1 more source

Impact of antigen identification on transplant free survival in interstitial lung disease

open access: yesBMC Pulmonary Medicine, 2023
Introduction Antigen identification impacts diagnosis as well as prognosis in patients with hypersensitivity pneumonitis. An antigen may also be present in other etiologies of interstitial lung disease, however it is unknown whether identification ...
Margaret Kypreos   +3 more
doaj   +1 more source

Air pollution-induced epigenetic changes: disease development and a possible link with hypersensitivity pneumonitis

open access: yesEnvironmental science and pollution research international, 2021
Air pollution is a serious threat to our health and has become one of the major causes of many diseases including cardiovascular disease, respiratory disease, and cancer. The association between air pollution and various diseases has long been a topic of
Suranjana Mukherjee   +3 more
semanticscholar   +1 more source

Characterizing cellular heterogeneity in fibrotic hypersensitivity pneumonitis by single-cell transcriptional analysis

open access: yesCell Death Discovery, 2022
Fibrotic hypersensitivity pneumonitis (FHP) remains one of fatal interstitial pulmonary disease. Comprehensively dissecting the cellular heterogeneity of FHP paves the way for developing general gene therapeutic solutions for FHP.
Junyi Wang   +12 more
semanticscholar   +1 more source

Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis

open access: yesThorax, 2022
A subset of patients with hypersensitivity pneumonitis (HP) develop lung fibrosis that is clinically similar to idiopathic pulmonary fibrosis (IPF). To address the aetiological determinants of fibrotic HP, we investigated whether the common IPF genetic ...
H. Furusawa   +9 more
semanticscholar   +1 more source

Acute exacerbation of fibrotic hypersensitivity pneumonitis: incidence and outcomes

open access: yesRespiratory Research, 2021
Background Patients with fibrotic hypersensitivity pneumonitis (HP) show variable clinical courses, and some experience rapid deterioration (RD), including acute exacerbation (AE). However, little is known about AE in fibrotic HP.
Jieun Kang   +4 more
semanticscholar   +1 more source

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