Results 61 to 70 of about 91,296 (293)

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

MEETNet: Morphology-Edge Enhanced Triple-Cascaded Network for Infrared Small Target Detection

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Infrared small target detection is focused on accurately identifying tiny targets with low signal-to-noise ratio against complex backgrounds, representing a critical challenge in the field of infrared image processing. Existing approaches frequently fail
Enyu Zhao, Yu Shi, Nianxin Qu, Yulei Wang, Hang Zhao   +4 more
doaj   +1 more source

Nonlinear unmixing of hyperspectral images: Models and algorithms [PDF]

, 2013
When considering the problem of unmixing hyperspectral images, most of the literature in the geoscience and image processing areas relies on the widely used linear mixing model (LMM).
McLaughlin, Stephen; id_orcid, Hero, Alfred O, Jean-yves Tourneret, Cédric Richard, Hero, Alfred O., Dobigeon, Nicolas, McLaughlin, Steve, Bermudez, José Carlos M., Alfred O. Hero, Stephen Mclaughlin, Bermudez, José Carlos Moreira, Nicolas Dobigeon, Richard, Cédric, Tourneret, Jean-Yves, José Carlos M. Bermudez, Bermudez, José Carlos M   +14 more
core   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Deep&Dense Convolutional Neural Network for Hyperspectral Image Classification

Remote Sensing, 2018
Deep neural networks (DNNs) have emerged as a relevant tool for the classification of remotely sensed hyperspectral images (HSIs), with convolutional neural networks (CNNs) being the current state-of-the-art in many classification tasks.
Mercedes E. Paoletti, Juan M. Haut, Javier Plaza, Antonio Plaza   +3 more
doaj   +1 more source

Nanoscale Optical Inhomogeneities From Compositional Segregation Within Individual GaN‐on‐Si Quantum Wells

Advanced Science, EarlyView.
This work visualizes local variations in luminescence and relates them to nanoscale chemical inhomogeneities in single InxGa1−xN quantum wells. We demonstrate that the elemental segregation is only inherent to quantum wells with high indium content. Density functional theory shows this to be the result of strain‐induced phase stabilization, explaining ...
Jing‐Yang Chung, Tara P. Mishra, Zackaria Mahfoud, Thomas E. Gage, Jianguo Wen, Katherine P. Rice, Isabelle Martin, Li Zhang, Govindo J. Syaranamual, Stephen J. Pennycook, Silvija Gradečak, Pieremanuele Canepa, Michel Bosman   +12 more
wiley   +1 more source

Global Information and Structure Tensor Guided Collaborative Representation for Anomaly Detection

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Anomaly detection is susceptible to complex background and interference noise. Local anomaly detection and collaborative representation detection can effectively suppress background.
Meiping Song, Zhenyu Guo, Lan Li, Shihui Liu, Haimo Bao, Jiakang Li   +5 more
doaj   +1 more source

A Comprehensive Survey of Imbalance Correction Techniques for Hyperspectral Data Classification

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023
Land-cover classification is an important topic for remotely sensed hyperspectral (HS) data exploitation. In this regard, HS classifiers have to face important challenges, such as the high spectral redundancy, as well as noise, present in the data, and ...
Mercedes E. Paoletti, Oscar Mogollon-Gutierrez, Sergio Moreno-Alvarez, Jose Carlos Sancho, Juan M. Haut   +4 more
doaj   +1 more source

Hyperspectral Unmixing Overview: Geometrical, Statistical, and Sparse Regression-Based Approaches [PDF]

, 2012
Imaging spectrometers measure electromagnetic energy scattered in their instantaneous field view in hundreds or thousands of spectral channels with higher spectral resolution than multispectral cameras.
Paul Gader, Jocelyn Chanussot, Qian Du, Gader, Paul, Antonio Plaza, José M. Bioucas-dias, Chanussot, Jocelyn, Dobigeon, Nicolas, Plaza, Antonio, Du, Qian, Mario Parente, Bioucas-Dias, José M., Nicolas Dobigeon, Parente, Mario   +13 more
core   +1 more source

Label‐Free Myelin Fingerprinting: An Adult Human Post‐Mortem Brain Slice Platform via Coherent Anti‐Stokes Raman Spectroscopy

Advanced Science, EarlyView.
A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki, Jeroen P. Korterik, Femke Tjebbes, Geert J. Schenk, Herman L. Offerhaus, Antonio Luchicchi   +5 more
wiley   +1 more source