Results 51 to 60 of about 8,171 (214)

Intestinal and Multivisceral Transplantation: Where We Stand Today

open access: yesPediatric Transplantation, Volume 30, Issue 1, January 2026.
ABSTRACT Intestinal and multivisceral transplantation has evolved from an experimental to a life‐saving procedure for children and adults with complications of gut failure (GF). Suboptimal long‐term outcomes of transplant elicit recent advances in surgical and medical gut rehabilitation along with the introduction of glucagon‐like peptide‐2 (GLP‐2 ...
Mohamed Maklad   +5 more
wiley   +1 more source

SPLENIC ARTERY EMBOLIZATION IN PATIENTS UNDERGOING ORTHOTOPIC LIVER TRANSPLANTATION

open access: yesВестник трансплантологии и искусственных органов, 2016
Aim: to analyze the results of embolization of the splenic artery in fi ve patients after orthotopic liver transplantation.Materials and methods. Embolization of the splenic artery was performed 6 times in fi ve (3.2%) of 158 patients who underwent ...
D. A. Granov   +5 more
doaj   +1 more source

Demand for human leukocyte antigen or human platelet antigen‐selected platelets: An observational study at Canadian Blood Services

open access: yesTransfusion, Volume 66, Issue 1, Page 114-122, January 2026.
Abstract Background Platelet transfusion refractoriness (PTR) is a clinically important condition. The Human Leukocyte Antigen and Human Platelet Antigen (HLA/HPA) Platelet Program at Canadian Blood Services (CBS) provides platelet products to support such patients.
Natasha Rickards   +5 more
wiley   +1 more source

Romiplostim therapy as a second‐line treatment before splenectomy for refractory immune thrombocytopenia in a cirrhotic patient with iatrogenic Cushing syndrome secondary to corticosteroids

open access: yesClinical Case Reports, 2017
Key Clinical Message Our case report discusses the usefulness of administering romiplostim as a second‐line treatment before splenectomy in a cirrhotic patient with immune thrombocytopenia who developed corticosteroid‐induced Cushing's syndrome ...
Teresa Casanovas Taltavull   +1 more
doaj   +1 more source

Purine Nucleoside Phosphorylase Inhibition Rebalances Purine Metabolism and Attenuates Organ Damage in Sickle Cell Mice

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 24, December 2025.
ABSTRACT Red blood cells (RBCs) contain the highest purine nucleoside phosphorylase (PNP) level per cell volume, yet the role of PNP in the pathogenesis of sickle cell disease (SCD) is incompletely understood, highlighting an important gap in our knowledge of the disease.
Adekunle Emmanuel Alagbe   +5 more
wiley   +1 more source

Beyond Hepatitis: A Rare Case of Multisystem Langerhans Cell Histiocytosis in a Child

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder involving abnormal proliferation of dendritic cells, with clinical presentations ranging from isolated lesions to life‐threatening multisystem involvement. This case report describes a 26‐month‐old girl who presented with progressive jaundice, fever, hepatomegaly, pruritic scalp
Dilip Neupane   +4 more
wiley   +1 more source

Extracellular Vesicle Characteristics in β-thalassemia as Potential Biomarkers for Spleen Functional Status and Ineffective Erythropoiesis

open access: yesFrontiers in Physiology, 2018
β-thalassemia major (β-TM) is a therapeutically challenging chronic disease in which ineffective erythropoiesis is a main pathophysiological factor. Extracellular vesicles (EVs) are membrane-enclosed vesicles released by cells into biological fluids ...
Carina Levin   +9 more
doaj   +1 more source

Splenic Arterial Embolization for Trauma and Beyond: A Case Series

open access: yesVascular Specialist International
Splenic artery embolization plays an important role in the management of various medical and surgical conditions that are non-traumatic in etiology, in addition to its well-established and widely discussed role in managing splenic trauma. In nontraumatic
Chun Hin Choy   +4 more
doaj   +1 more source

Activation of MEK‐ERK‐c‐MYC signaling pathway promotes splenic M2-like macrophage polarization to inhibit PHcH-liver cirrhosis

open access: yesFrontiers in Immunology
IntroductionPortal hypertension combined with hypersplenism (PHcH) is the main cause of hypocytosis and esophagogastric variceal hemorrhage in patients with liver cirrhosis.
Wang Guihu   +26 more
doaj   +1 more source

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