Results 51 to 60 of about 7,429 (165)

SUCCESSFUL CHEMOTHERAPY ADMINISTRATION DESPITE HYPERSPLENISM AND PANCYTOPENIA: A CASE OF METASTATIC RECTAL ADENOCARCINOMA

Hematology, Transfusion and Cell Therapy
Introduction: Cytopenias in oncology patients present a significant barrier to the administration of chemotherapy. Hypersplenism is one of the leading causes of cytopenia.
Adil Uğur Kaan Güngör, Abdurrahman Aykut, Berksoy Sahin, Hatice Asoğlu Rüzgar   +3 more
doaj   +1 more source

Clinical Heterogeneity of Refractory Ascites After Pediatric Liver Transplantation Modulates Allograft Rejection Risk

MedComm, Volume 7, Issue 9, September 2026.
Refractory ascites (RA) post‐pediatric LT is stratified into two subtypes: Type I (portal hypertension‐driven) and Type II (immune‐mediated). Type I is linked to low GRWR and hypersplenism, while Type II involves ABO incompatibility and early T‐cell activation (elevated sIL‐2R). Type II increases rejection risk (OR = 2.212).
Bingran Wang, Yunmu Gao, Jiaqi Song, Qi Pan, Aiwei Zhou, Hongyuan Liu, Wanglong Xiao, Zhicong Zhao, Taihua Yang, Chen Chen, Zhipeng Zong, Tao Zhou, Yi Luo, Yongbo Liu, Yuan Liu, Qiang Xia   +15 more
wiley   +1 more source

Mechanistic Insights Into Hepatotoxicity‐Induced Liver Cirrhosis and Anemia: Iron Dysregulation, the Hepcidin–Ferroportin Axis, and Emerging Therapeutic Strategies

Organ Medicine, Volume 3, Issue 3, Page 171-185, September 2026.
Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley   +1 more source

Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies

European Journal of Haematology, Volume 117, Issue 3, Page 682-690, September 2026.
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara, Katlyn G. McKay, Harold N. Lovvorn III, Joseph C. Fusco   +3 more
wiley   +1 more source

Comparison of Thrombocytopenia and Splenomegaly in Locally Advanced Rectal Cancer Patients Receiving Total Neoadjuvant Therapy With and Without Immunotherapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Thrombocytopenia is a common toxicity of oxaliplatin‐based chemotherapy and may be linked to hepatic sinusoidal obstruction and splenic enlargement. In the TORCH trial, adding PD‐1 blockade to an oxaliplatin‐containing total neoadjuvant therapy (TNT) regimen improved tumor response in patients with locally advanced rectal cancer ...
Shuwen Li, Mingxu Yan, Qiong Ma, Yiqun Sun, Zhen Zhang, Lijun Shen, Juefeng Wan, Hui Zhang, Ruiyan Wu, Fan Xia, Yaqi Wang   +10 more
wiley   +1 more source

Integrating Gaucher disease (GD) into mainstream hematological curriculum training

HemaSphere, Volume 10, Issue 10, October 2026.
Colm Bradley, Argiris Symeonidis, Sam Salek, Nkemdirim Jacob   +3 more
wiley   +1 more source

Radiofrequency ablation and laparoscopic splenectomy for the treatment of small hepatocellular carcinoma with hypersplenism

Zhongguo aizheng zazhi, 2016
Background and purpose: Liver cancer resection and splenectomy are the main methods to treat hepatocellular carcinoma and hypersplenism. The aim of this study was to discuss the safety and feasibility of simultaneous radiofrequency ablation (RFA) and ...
曾新桃, 罗　华, 张　伟
doaj  

Hypersplenism.

The Nebraska state medical journal, 2004
G L, REYES, A E, JOSE
  +18 more sources

Organ-preserving treatment of splenomegaly in portal hypertension: clinical outcomes 12 months after partial embolization of the splenic artery

Український журнал клінічної хірургії
Objective. To evaluate the hematological effects and clinical efficacy of partial splenic artery embolization in the treatment of splenomegaly and hypersplenism in patients with portal hypertension caused by chronic liver diseases.
S. M. Kozlov, V. A. Kondratiuk
doaj   +1 more source

Romiplostim therapy as a second‐line treatment before splenectomy for refractory immune thrombocytopenia in a cirrhotic patient with iatrogenic Cushing syndrome secondary to corticosteroids

Clinical Case Reports, 2017
Key Clinical Message Our case report discusses the usefulness of administering romiplostim as a second‐line treatment before splenectomy in a cirrhotic patient with immune thrombocytopenia who developed corticosteroid‐induced Cushing's syndrome ...
Teresa Casanovas Taltavull, Maria Carmen Peña‐Cala   +1 more
doaj   +1 more source