Results 201 to 210 of about 504,948 (315)

Development of a population pharmacokinetic model using combined paediatric and adult data for four pulmonary arterial hypertension drugs

British Journal of Clinical Pharmacology, EarlyView.
Aims Pulmonary arterial hypertension (PAH) is a syndrome characterized by elevated pulmonary artery pressure. We developed a population pharmacokinetic (PPK) model using combined plasma drug concentration data from Japanese paediatric (<15 years) and adult (≥15 years) patients with PAH to investigate the pharmacokinetic characteristics of PAH ...
Motoyasu Miura, Shimako Tanaka, Ririka Aihara, Shun Yamamoto, Yasumi Nakashima, Yasuharu Kashiwagura, Akio Hakamata, Sachiko Miyakawa, Mariko Tatsuguchi, Keiichi Odagiri, Noriyuki Namiki, Naoki Inui, Hiroshi Watanabe, Shinya Uchida   +13 more
wiley   +1 more source

Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms.

Physiol Rev
Drury ER, Wu J, Gigliotti JC, Le TH.
europepmc   +1 more source

Atypical case of renovascular hypertension associated with median arcuate ligament syndrome in a paediatric patient. [PDF]

Urol Case Rep
Wojciechowska E, Garnier H, Znaniecki Ł, Załuska-Leśniewska I, Sinacka K, Świętoń D, Czauderna P, Gołębiewski A.   +7 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

T-cells regulate albuminuria but not hypertension, renal histology, or the medullary transcriptome in the Dahl SSCD247^+/+ rat.

Am J Physiol Renal Physiol
Dayton A, Almutlaq RN, Guntipally S, Ross J, Evans LC.   +4 more
europepmc   +1 more source

The Role of Renal Denervation in the Treatment of Hypertension in Canada: A Case-Based Discussion from the Canadian Hypertension Specialists Society. [PDF]

Am J Hypertens
Padwal RS, Dorsch M, Tobe S, Ringrose J, Schiffrin EL, Feldman RD, Prasad B, Leung AA, Dubrofsky L, Tran KC, Madan M, Machan L, Khan N.   +12 more
europepmc   +1 more source

Pre‐Existing and New‐Onset Atrial Fibrillation in Patients Undergoing Transcatheter Aortic Valve Implantation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Atrial fibrillation (AF) is a frequent comorbidity in patients with severe aortic valve stenosis undergoing transcatheter aortic valve implantation (TAVI). In addition, new‐onset AF can occur after TAVI. However, data on how AF affects outcomes in patients undergoing TAVI remain conflicting.
Kimberley I. Hemelrijk, Astrid C. van Nieuwkerk, Philomene J. Vojacek, Livia Gheorge, Didier Tchétché, Fabio S. de Brito Jr., Marco Barbanti, Ran Kornowski, Azeem Latib, Augusto D'Onofrio, Flavio Ribichini, Geoffrey Yanes Bowden, Nicolas Dumonteil, Rogerio Sarmento Leite, Samantha Sartori, Paola D'Errigo, Giuseppe Tarantini, Stefano Andreaggi, Katia Orvin, Matteo Pagnesi, Lluis Asmarats, George Dangas, Roxana Mehran, Ronak Delewi   +23 more
wiley   +1 more source

Atherosclerotic Renovascular Disease: A Re-evaluation of Lesion Severity and Intervention. [PDF]

Kidney Med
Woittiez AJ, Postma CT, de Leeuw PW.
europepmc   +1 more source

Influence of the Residual Gensini Score on Prognosis of Patients With ST‐Elevation Myocardial Infarction

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The residual Gensini score (rGS) was developed to quantify the severity of coronary atheroma burden after coronary revascularisation. The predictive value of the rGS for clinical outcomes in patients with ST‐segment elevation myocardial infarction (STEMI) remains unexplored.
Batric Popovic, Nassima Djaballah, Mirela Tomic, Renaud Fay, Victorine Fraichot, Florian Eggenspieler, Pierre Adrien Metzdorf, Jeanne Varlot, Edoardo Camenzind   +8 more
wiley   +1 more source

Feasibility and Safety of Distal Transradial Access in Patients With Out‐of‐Hospital Cardiac Arrest Undergoing Emergency PCI: A Single‐Center Retrospective Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Distal transradial access (dTRA) has gained attention for its lower risk of vascular complications compared to conventional transradial access (TRA). However, its feasibility and safety in patients with out‐of‐hospital cardiac arrest (OHCA) undergoing emergency percutaneous coronary intervention (PCI) remain uncertain.
Shiori Kawakami, Norimasa Taniguchi, Takeshi Yamada, Tetsuya Hata, Shunsuke Nakajima, Fumihiko Sano, Hideya Nakano, Mitusko Yokouchi, Aiko Ko, Akihiko Takahashi   +9 more
wiley   +1 more source