Results 51 to 60 of about 18,931 (219)
The FEBS Journal, EarlyView.Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory +3 more
wiley +1 more source
Angiotensin II and angiotensin-(1-7) in paraventricular nucleus modulate cardiac sympathetic afferent reflex in renovascular hypertensive rats. [PDF]
PLoS ONE, 2012 The enhanced cardiac sympathetic afferent reflex (CSAR) is involved in the sympathetic activation that contributes to the pathogenesis and progression of hypertension. Activation of AT(1) receptors by angiotension (Ang) II in the paraventricular nucleus (
Hai-Jian Sun +4 more
doaj +1 more source
The Role of Natriuretic peptides in Renovascular Hypertension and its correlation with the Evolution of Myocardial Hypertrophy [PDF]
, 2010 The interactions between pressure and volume overload that occur in hypertension lead to different patterns of cardiac hypertrophy and to increase in natriuretic peptides (NPs).
Cavallero, Carmen Susana +4 more
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Brain and Behavior, Volume 16, Issue 5, May 2026.This study, through an analysis of neuroimaging markers, biomarkers of white matter damage, and the volume of the hippocampal fimbria (a white matter structure) in patients with cerebral small vessel disease (CSVD), revealed that the protective effect of statin therapy against white matter damage in CSVD patients is independent of its lipid‐lowering ...
Rui Wang +5 more
wiley +1 more source
Experimental rat models of chronic allograft nephropathy: a review [PDF]
, 2014 Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
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Physiological Reports, Volume 14, Issue 9, May 2026.Abstract We developed a noninvasive approach to measure vascular responses to sympathetic stimuli. We hypothesized that standing, handgrip exercise, or cold exposure would raise blood pressure (BP) and lower renal vascular conductance (RVC). BP was recorded continuously and renal arterial velocity was measured using renal Doppler ultrasound.
Mohamed H. Ibrahim +7 more
wiley +1 more source
Hypertensive Crises in the Adolescent: Evaluation of Suspected Renovascular Hypertension
Acta Medica Indonesiana, 2016 Hypertensive crises can be divided into two categories as hypertensive emergency and hypertensive urgency. Most authorities have defined hypertensive emergency as a situation that requires immediate reduction in blood pressure (BP) with parenteral ...
Indra Wijaya, Parlindungan Siregar
doaj +4 more sources
Renovascular hypertension: screening and modern management [PDF]
, 2017 The diagnosis and management of patients with renovascular disease and hypertension continue to elude healthcare providers. The advent of novel imaging and interventional techniques, and increased understanding of the pathways leading to irreversible ...
Baumgartner, Iris, Lerman, Lilach O.
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Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood-pressure independent effect [PDF]
, 2016 Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by ...
Carletti, R +5 more
core +1 more source
Hypertensive Urgency and Pulmonary Infiltrates: A Report of Three Cases
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Hypertensive urgency is commonly attributed to medication nonadherence, progression of essential hypertension, or secondary causes. However, in some patients, no clear precipitating factor is identified, despite repeated evaluations and the absence of target organ damage. Subclinical inflammatory conditions have been hypothesized as potential,
Mónica Contreras‐Moreira
wiley +1 more source