Results 1 to 10 of about 492,096 (168)

Surgical procedures suppress autophagic flux in the kidney

open access: yesCell Death and Disease, 2021
Many surgical models are used to study kidney and other diseases in mice, yet the effects of the surgical procedure itself on the kidney and other tissues have not been elucidated.
Carolyn N. Brown   +11 more
doaj   +1 more source

A 6-Month clinical practice pilot study of sucroferric oxyhydroxide on nutritional status in patients on peritoneal dialysis

open access: yesBMC Nephrology, 2022
Background Hyperphosphatemia is common in patients on peritoneal dialysis (PD). Restricting dietary phosphorus often leads to a decrease in protein intake, which may result in hypoalbuminemia. The high pill burden of phosphate binders may also contribute
Luis Perez   +7 more
doaj   +1 more source

Integrative Volume Status Assessment

open access: yesPOCUS Journal, 2022
Volume status assessment is a critical but challenging clinical skill and is especially important for the management of patients in the emergency department, intensive care unit, and dialysis unit where accurate intravascular assessment is necessary to ...
David Kearney   +2 more
doaj   +1 more source

Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development

open access: yesNature Communications, 2023
The contribution of transposable elements and endogenous retroviruses to renal fibroinflammation is currently unknown. Here, the authors comprehensively profile the expression of transposable elements and endogenous retroviruses (ERVs) in kidneys of ...
Poonam Dhillon   +9 more
doaj   +1 more source

Sex hormones and the risk of cardiovascular disease and mortality in male and female patients with chronic kidney disease: A systematic review and meta‐analysis

open access: yesPhysiological Reports, 2022
Patients with chronic kidney disease (CKD) commonly experience sex hormone disturbances, which may be associated with the risk of cardiovascular disease (CVD) and mortality. This review aimed to systematically evaluate current findings on the association
Ester S. Oh   +4 more
doaj   +1 more source

A case report of pre-eclampsia-like endothelial injury in the kidney of an 85-year-old man treated with ibrutinib

open access: yesBMC Nephrology, 2022
Background Glomerular endotheliosis is the pathognomonic glomerular lesion in pre-eclampsia that has also been described in those taking tyrosine kinase inhibitors for cancer treatment.
Amy Li   +4 more
doaj   +1 more source

GPAT4-Generated Saturated LPAs Induce Lipotoxicity through Inhibition of Autophagy by Abnormal Formation of Omegasomes

open access: yesiScience, 2020
Summary: Excessive levels of saturated fatty acids are toxic to vascular smooth muscle cells (VSMCs). We previously reported that mice lacking VSMC-stearoyl-CoA desaturase (SCD), a major enzyme catalyzing the detoxification of saturated fatty acids ...
Yuji Shiozaki   +5 more
doaj   +1 more source

Renal metabolism and hypertension [PDF]

open access: yesNature Communications, 2021
AbstractHypertension is a leading risk factor for disease burden worldwide. The kidneys, which have a high specific metabolic rate, play an essential role in the long-term regulation of arterial blood pressure. In this review, we discuss the emerging role of renal metabolism in the development of hypertension.
Zhongmin Tian, Mingyu Liang
openaire   +3 more sources

Fructose increases risk for kidney stones: potential role in metabolic syndrome and heat stress

open access: yesBMC Nephrology, 2018
Background Fructose intake, mainly as table sugar or high fructose corn syrup, has increased in recent decades and is associated with increased risk for kidney stones.
Richard J. Johnson   +13 more
doaj   +1 more source

Reducing disparities in kidney transplantation for Spanish-speaking patients through creation of a dedicated center

open access: yesBMC Nephrology, 2022
Introduction Hispanic Americans receive disproportionately fewer organ transplants than non-Hispanic whites. In 2018, the Hispanic Kidney Transplant Program (HKTP) was established as at the University of Colorado Hospital (UCH).
Madhura Pande   +4 more
doaj   +1 more source

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