Results 21 to 30 of about 2,652,994 (308)

Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial.

The Lancet, 2018
BACKGROUND Early studies suggest that radiofrequency-based renal denervation reduces blood pressure in patients with moderate hypertension. We investigated whether an alternative technology using endovascular ultrasound renal denervation reduces ...
M. Azizi, R. Schmieder, F. Mahfoud, M. Weber, J. Daemen, J. Davies, J. Basile, Ajay J. Kirtane, Yale Wang, M. Lobo, M. Saxena, L. Feyz, F. Rader, Philipp Lurz, J. Sayer, M. Sapoval, T. Levy, Kintur Sanghvi, J. Abraham, Andrew S P Sharp, Naomi D L Fisher, M. Bloch, Helen Reeve-Stoffer, Leslie A. Coleman, C. Mullin, L. Mauri   +25 more
semanticscholar   +1 more source

Renal Inflammation in DOCA-Salt Hypertension: Role of Renal Nerves and Arterial Pressure

HYPERTENSION, 2019
Recent reports indicate that, in addition to treating hypertension, renal denervation (RDN) also mitigates renal inflammation. However, because RDN decreases renal perfusion pressure, it is unclear whether these effects are because of the direct effects ...
C. Banek, Madeline M Gauthier, D. Van Helden, G. Fink, J. Osborn   +4 more
semanticscholar   +1 more source

Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension

Cardiovascular Research, 2018
Aims Renal inflammation, leading to fibrosis and impaired function is a major contributor to the development of hypertension. The NLRP3 inflammasome mediates inflammation in several chronic diseases by processing the cytokines pro-interleukin (IL)-1β and
S. Krishnan, Y. H. Ling, Brooke M. Huuskes, D. Ferens, N. Saini, Christopher T. Chan, H. Diep, M. Kett, C. Samuel, B. Kemp-Harper, A. Robertson, M. Cooper, K. Peter, E. Latz, A. Mansell, C. Sobey, G. Drummond, Antony Vinh   +17 more
semanticscholar   +1 more source

Role of the Sympathetic Nervous System and Its Modulation in Renal Hypertension

Frontiers in Medicine, 2018
The kidneys are densely innervated with renal efferent and afferent nerves to communicate with the central nervous system. Innervation of major structural components of the kidneys, such as blood vessels, tubules, the pelvis, and glomeruli, forms a ...
Y. Sata, G. Head, K. Denton, C. May, M. Schlaich   +4 more
semanticscholar   +1 more source

OBESITY-INDUCED HYPERTENSION: INTERACTION OF NEUROHUMORAL AND RENAL MECHANISMS

Circulation Research, 2015
Excess weight gain, especially when associated with increased visceral adiposity, is a major cause of hypertension, accounting for 65–75% of the risk for human primary (essential) hypertension. Increased renal tubular sodium reabsorption impairs pressure
J. Hall, Jussara M. do Carmo, A. D. da Silva, Zhen Wang, Michael E. Hall   +4 more
semanticscholar   +1 more source

The cuffless SOMNOtouch NIBP device shows poor agreement with a validated oscillometric device during 24‐h ambulatory blood pressure monitoring

The Journal of Clinical Hypertension, 2021
Repeated cuff‐based blood pressure (BP) measurements may cause discomfort resulting in stress and erroneous recording values. SOMNOtouch NIBP is an alternative cuff‐less BP measurement device that calculates changes in BP based on changes in pulse ...
Jakob Nyvad, Kent L. Christensen, Niels Henrik Buus, Mark Reinhard   +3 more
doaj   +1 more source

Rehydration with fructose worsens dehydration-induced renal damage

BMC Nephrology, 2018
Background Increasing evidence suggests heat stress induced chronic kidney disease (CKD) may be mediated by endogenous fructose generation and may be exacerbated by rehydration by fructose-containing solutions.
Tamara Milagres, Fernando E. García-Arroyo, Miguel A. Lanaspa, Gabriela Garcia, Takuji Ishimoto, Ana Andres-Hernando, Masanari Kuwabara, Thomas Jensen, Yuka Sato, Jason Glaser, Laura G. Sánchez-Lozada, Richard J. Johnson, Carlos Roncal-Jimenez   +12 more
doaj   +1 more source

Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin–angiotensin system

Journal of Hypertension, 2017
Objectives: Butyrate, a short-chain fatty acid, is the end product of the fermentation of complex carbohydrates by the gut microbiota. Recently, sodium butyrate (NaBu) has been found to play a protective role in a number of chronic diseases.
Lei Wang, Qing Zhu, Aihua Lu, Xiaofen Liu, Linlin Zhang, Chuanming Xu, Xiyang Liu, Haobo Li, Tianxin Yang   +8 more
semanticscholar   +1 more source

Hypertension in Diabetes: An Update of Basic Mechanisms and Clinical Disease

HYPERTENSION, 2021
Epidemiological studies have documented that insulin resistance and diabetes not only constitute metabolic abnormalities, but also predispose to hypertension, vascular stiffness and associated cardiovascular disease.
Guanghong Jia, J. Sowers
semanticscholar   +1 more source

Postbiopsy arteriovenous fistula in renal allograft: An ultrasound case study

Clinical Case Reports, 2019
Key Clinical Message Arteriovenous fistula is a well‐known but rarely diagnosed complication of percutaneous renal biopsy. On Doppler sonography, these fistulae are characterized by a region of high velocity shifts and random color assignment due to ...
Harini Bejjanki, Alfonso H. Santos, Abhilash Koratala   +2 more
doaj   +1 more source