Results 11 to 20 of about 504,948 (315)

Surgical procedures suppress autophagic flux in the kidney

Cell Death and Disease, 2021
Many surgical models are used to study kidney and other diseases in mice, yet the effects of the surgical procedure itself on the kidney and other tissues have not been elucidated.
Carolyn N. Brown, Daniel Atwood, Deepak Pokhrel, Sara J. Holditch, Christopher Altmann, Nataliya I. Skrypnyk, Jennifer Bourne, Jelena Klawitter, Judith Blaine, Sarah Faubel, Andrew Thorburn, Charles L. Edelstein   +11 more
doaj   +1 more source

A 6-Month clinical practice pilot study of sucroferric oxyhydroxide on nutritional status in patients on peritoneal dialysis

BMC Nephrology, 2022
Background Hyperphosphatemia is common in patients on peritoneal dialysis (PD). Restricting dietary phosphorus often leads to a decrease in protein intake, which may result in hypoalbuminemia. The high pill burden of phosphate binders may also contribute
Luis Perez, Zhiying You, Isaac Teitelbaum, Emily S Andrews, Rachael Reddin, Lorena Ramirez-Renteria, Gabriela Wilson, Jessica Kendrick   +7 more
doaj   +1 more source

Integrative Volume Status Assessment

POCUS Journal, 2022
Volume status assessment is a critical but challenging clinical skill and is especially important for the management of patients in the emergency department, intensive care unit, and dialysis unit where accurate intravascular assessment is necessary to ...
David Kearney, Nathaniel Reisinger, Sadichhya Lohani   +2 more
doaj   +1 more source

Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development

Nature Communications, 2023
The contribution of transposable elements and endogenous retroviruses to renal fibroinflammation is currently unknown. Here, the authors comprehensively profile the expression of transposable elements and endogenous retroviruses (ERVs) in kidneys of ...
Poonam Dhillon, Kelly Ann Mulholland, Hailong Hu, Jihwan Park, Xin Sheng, Amin Abedini, Hongbo Liu, Allison Vassalotti, Junnan Wu, Katalin Susztak   +9 more
doaj   +1 more source

Sex hormones and the risk of cardiovascular disease and mortality in male and female patients with chronic kidney disease: A systematic review and meta‐analysis

Physiological Reports, 2022
Patients with chronic kidney disease (CKD) commonly experience sex hormone disturbances, which may be associated with the risk of cardiovascular disease (CVD) and mortality. This review aimed to systematically evaluate current findings on the association
Ester S. Oh, Cortney N. Steele, Zhiying You, Kristen L. Nowak, Anna J. Jovanovich   +4 more
doaj   +1 more source

A case report of pre-eclampsia-like endothelial injury in the kidney of an 85-year-old man treated with ibrutinib

BMC Nephrology, 2022
Background Glomerular endotheliosis is the pathognomonic glomerular lesion in pre-eclampsia that has also been described in those taking tyrosine kinase inhibitors for cancer treatment.
Amy Li, Sophia L. Ambruso, Ozgur Akin Oto, Marc Barry, Charles L. Edelstein   +4 more
doaj   +1 more source

GPAT4-Generated Saturated LPAs Induce Lipotoxicity through Inhibition of Autophagy by Abnormal Formation of Omegasomes

iScience, 2020
Summary: Excessive levels of saturated fatty acids are toxic to vascular smooth muscle cells (VSMCs). We previously reported that mice lacking VSMC-stearoyl-CoA desaturase (SCD), a major enzyme catalyzing the detoxification of saturated fatty acids ...
Yuji Shiozaki, Shinobu Miyazaki–Anzai, Kayo Okamura, Audrey L. Keenan, Masashi Masuda, Makoto Miyazaki   +5 more
doaj   +1 more source

Severe hypertension induces disturbances of renal autoregulation [PDF]

, 1992
To study if the severity of hypertension could be associated with disturbances of the autoregulation of renal blood flow and glomerular filtration, we compared the renal hemodynamic and functional responses to acute blood pressure reductions of a group ...
Ramos, Oswaldo L., Tavares, Agostinho, Almeida, Jose Bruno de, Cezareti, Mário L., Saragoca, Manoel A., Draibe, Sérgio A.   +5 more
core   +2 more sources

Joint UK societies' 2014 consensus statement on renal denervation for resistant hypertension. [PDF]

, 2014
Resistant hypertension continues to pose a major challenge to clinicians worldwide and has serious implications for patients who are at increased risk of cardiovascular morbidity and mortality with this diagnosis.
Matson, M, Williams, B, Paton, JF, Kapil, Vikas, Moss, J, Simpson, Iain, Knight, Charles, Poulter, Neil, Poulter, N, Collier, David, de Belder, Mark A, Caulfield, Mark J, Matson, Matthew, Simpson, I, Cleveland, Trevor, Deanfield, John, Lobo, MD, de Belder, MA, Williams, Bryan, Lobo, Melvin D, Moss, Jonathan, Caulfield, MJ, Kapil, V, Knight, C, Paton, Julian F R, Dasgupta, I, Paton, JFR, Deanfield, J, ?, ?, Cleveland, T, Collier, D, Dasgupta, Indranil   +31 more
core   +1 more source

Renal Denervation and Hypertension [PDF]

American Journal of Hypertension, 2011
Essential hypertension remains one of the biggest challenges in medicine with an enormous impact on both individual and society levels. With the exception of relatively rare monogenetic forms of hypertension, there is now general agreement that the condition is multifactorial in nature and hence requires therapeutic approaches targeting several aspects
Markus P, Schlaich, Henry, Krum, Paul A, Sobotka, Murray D, Esler   +3 more
openaire   +2 more sources