Results 11 to 20 of about 2,652,994 (308)

Sex hormones and the risk of cardiovascular disease and mortality in male and female patients with chronic kidney disease: A systematic review and meta‐analysis

open access: yesPhysiological Reports, 2022
Patients with chronic kidney disease (CKD) commonly experience sex hormone disturbances, which may be associated with the risk of cardiovascular disease (CVD) and mortality. This review aimed to systematically evaluate current findings on the association
Ester S. Oh   +4 more
doaj   +1 more source

A case report of pre-eclampsia-like endothelial injury in the kidney of an 85-year-old man treated with ibrutinib

open access: yesBMC Nephrology, 2022
Background Glomerular endotheliosis is the pathognomonic glomerular lesion in pre-eclampsia that has also been described in those taking tyrosine kinase inhibitors for cancer treatment.
Amy Li   +4 more
doaj   +1 more source

GPAT4-Generated Saturated LPAs Induce Lipotoxicity through Inhibition of Autophagy by Abnormal Formation of Omegasomes

open access: yesiScience, 2020
Summary: Excessive levels of saturated fatty acids are toxic to vascular smooth muscle cells (VSMCs). We previously reported that mice lacking VSMC-stearoyl-CoA desaturase (SCD), a major enzyme catalyzing the detoxification of saturated fatty acids ...
Yuji Shiozaki   +5 more
doaj   +1 more source

Renal Denervation and Hypertension [PDF]

open access: yesAmerican Journal of Hypertension, 2011
Essential hypertension remains one of the biggest challenges in medicine with an enormous impact on both individual and society levels. With the exception of relatively rare monogenetic forms of hypertension, there is now general agreement that the condition is multifactorial in nature and hence requires therapeutic approaches targeting several aspects
Markus P, Schlaich   +3 more
openaire   +2 more sources

Fructose increases risk for kidney stones: potential role in metabolic syndrome and heat stress

open access: yesBMC Nephrology, 2018
Background Fructose intake, mainly as table sugar or high fructose corn syrup, has increased in recent decades and is associated with increased risk for kidney stones.
Richard J. Johnson   +13 more
doaj   +1 more source

Reducing disparities in kidney transplantation for Spanish-speaking patients through creation of a dedicated center

open access: yesBMC Nephrology, 2022
Introduction Hispanic Americans receive disproportionately fewer organ transplants than non-Hispanic whites. In 2018, the Hispanic Kidney Transplant Program (HKTP) was established as at the University of Colorado Hospital (UCH).
Madhura Pande   +4 more
doaj   +1 more source

Activating transcription factor 4 regulates stearate-induced vascular calcification

open access: yesJournal of Lipid Research, 2012
Previously, we reported that stearate, a saturated fatty acid, promotes osteoblastic differentiation and mineralization of vascular smooth muscle cells (VSMC).
Masashi Masuda   +5 more
doaj   +1 more source

Hypertension as Cardiovascular Risk Factor in Chronic Kidney Disease

open access: yesCirculation Research, 2023
Hypertension is the leading modifiable cause of premature death and hence one of the global targets of World Health Organization for prevention. Hypertension also affects the great majority of patients with chronic kidney disease (CKD). Both hypertension
M. Burnier, A. Damianaki
semanticscholar   +1 more source

Patterns of vascular calcification in patients with end‐stage renal disease and calcific uremic arteriolopathy

open access: yesClinical Case Reports, 2017
Key Clinical Message Calcific uremic arteriolopathy or calciphylaxis is a rare and potentially fatal condition, which manifests as skin ischemia and necrosis, usually seen in patients with end‐stage renal disease.
Abhilash Koratala   +3 more
doaj   +1 more source

Deletion of TLR4 reduces apoptosis and improves histology in a murine kidney transplant model

open access: yesScientific Reports, 2021
Acute kidney injury (AKI) after transplantation of human deceased donor kidneys is associated with upregulation of tubular toll like receptor 4 (TLR4), but whether TLR4 is required for AKI is unknown.
Swati Jain   +4 more
doaj   +1 more source

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