Results 31 to 40 of about 721,205 (215)

Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood-pressure independent effect [PDF]

, 2016
Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by ...
Carletti, R, Castoldi, G, DI GIOIA, Cira Rosaria Tiziana, Roma, F, Stella, A., Zerbini, G   +5 more
core   +1 more source

Angiotensin II‐induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor‐alpha type 1 receptor

Physiological Reports, 2021
In hypertension induced by angiotensin II (AngII) administration with high salt (HS) intake, intrarenal angiotensinogen (AGT) and tumor necrosis factor‐alpha (TNF‐α) levels increase.
Dewan S. A. Majid, Eamonn Mahaffey, Alexander Castillo, Minolfa C. Prieto, L. Gabriel Navar   +4 more
doaj   +1 more source

Blood pressure changes after renal denervation at 10 European expert centers [PDF]

, 2013
We did a subject-level meta-analysis of the changes (Δ) in blood pressure (BP) observed 3 and 6 months after renal denervation (RDN) at 10 European centers. Recruited patients (n=109; 46.8% women; mean age 58.2 years) had essential hypertension confirmed
Adiyaman, A, Andersson, Bert,, Azizi, M, Baelen, M, Burnier, M, Elvan, A, Fadl Elmula, F E, Gothenburg University., Göteborgs universitet., Jacobs, L, Jin, Y, Jokhaji, F, Kahan, T, Kjeldsen, S E, Mark, P B, Monge, M, Pechère-Bertschi, A, Persu, A, Renkin, J, Rosa, J, Sapoval, M, Severino, F, Staessen, J A, Taylor, A, Völz, Sebastian,, Widimský, P, Wuerzner, G   +26 more
core   +3 more sources

Not all that is red is blood: a curious case of chromaturia

Clinical Case Reports, 2018
Key Clinical Message Hydroxocobalamin causes reddish discoloration of the urine, mimicking hematuria. Clinicians should be aware of this common side effect of the rarely used drug to prevent unnecessary consultations and work‐up. Additional benign causes
Abhilash Koratala, Gajapathiraju Chamarthi, Mark S. Segal   +2 more
doaj   +1 more source

Know your patients’ history; spleno-renal infarction as a presentation of infective endocarditis

Clinics and Practice, 2017
Bacterial endocarditis is an infection of the endothelial surface of the heart, including heart valves and is potentially life threatening. Antibiotic prophylaxis is indicated prior to invasive procedures in patients with certain high-risk cardiac ...
Abhilash Koratala, Muhannad Leghrouz, Volodymyr Chornyy   +2 more
doaj   +1 more source

Metformin does not slow cyst growth in the PCK rat model of polycystic kidney disease

Physiological Reports, 2023
Metformin (MET) has the potential to activate p‐AMPK and block mTORC1‐induced proliferation of tubular cells in PKD kidneys. The aim of this study was to determine the effects of MET on cyst growth, kidney function, AMPK and mTOR signaling, and lactate ...
Ozgur A. Oto, Daniel J. Atwood, Anjana Chaudhary, Zhibin He, Amy S. Li, Michael F. Wempe, Charles L. Edelstein   +6 more
doaj   +1 more source

Renal artery stenosis-when to screen, what to stent? [PDF]

, 2014
Renal artery stensosis (RAS) continues to be a problem for clinicians, with no clear consensus on how to investigate and assess the clinical significance of stenotic lesions and manage the findings.
A Losito, A Persu, AH Cragg, Alison Severn, Antiplatelet Trialists’ Collaboration, AR Chade, AT Hirsch, B Bruyne De, B Drieghe, B Girolami, BC Jaarsveld van, BH Gray, C Chrysochou, C Chrysochou, C Rountas, CG Missouris, CJ Cooper, CJ Cooper, Claudine G. Jennings, CM Cheung, D Blondin, D Lao, D Mukherjee, DFJ Tollefson, DG Hackam, DP Slovut, DTNA Berg van den, E Balk, FH Messerli, GA McKenzie, GBC Vasbinder, GBC Vasbinder, GJ Williams, H Tan, H Weibull, Isla S. Mackenzie, J Ritchie, J Webster, JL Zhang, John G. Houston, JP Beregi, JV Smit, JW Olin, JW Olin, K Rocha-Singh, K Wheatley, KA Gillis, KJ Hansen, L Bax, L Trinquart, LD Dworkin, LE Ramsay, LM Messina, LU Mailloux, M Seddon, MC Bates, MJ Bloch, MT Caps, MW Burket, OW Kincaid, P Liang, PJ Conlon, PJG Ven van de, PJG Ven van de, Renal Association, S Anand, S Savard, S Willoteaux, Samira Bell, SC Textor, SC Textor, SC Textor, SJ Gandy, SJ Gandy, SM Begelman, SW Lim, T Jonason, Thomas M. MacDonald, TP Murphy, VS Silva, WJ Jean   +80 more
core   +4 more sources

An 88‐year‐old patient with ADPKD: underscoring the importance of risk factor modification

Clinical Case Reports, 2017
Key Clinical Message The mean age of onset of end‐stage renal disease (ESRD) in autosomal dominant polycystic kidney disease (ADPKD) is between 56 and 69.
Abhilash Koratala, Freddy R Malpartida, Amir Kazory   +2 more
doaj   +1 more source

Risk prediction to inform surveillance of chronic kidney disease in the US Healthcare Safety Net: a cohort study. [PDF]

, 2016
BackgroundThe capacity of electronic health record (EHR) data to guide targeted surveillance in chronic kidney disease (CKD) is unclear. We sought to leverage EHR data for predicting risk of progressing from CKD to end-stage renal disease (ESRD) to help ...
Chertow, Glenn M, Hall, Yoshio N, Himmelfarb, Jonathan, Maziarz, Marlena, Tuot, Delphine S, Xie, Yuxiang   +5 more
core   +2 more sources

Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice

Cell Reports, 2016
The kidney has a tremendous capacity to regenerate following injury, but factors that govern this response are still largely unknown. We isolated cells from mouse kidneys with high proliferative and multi-lineage differentiation capacity.
Hyun Mi Kang, Shizheng Huang, Kimberly Reidy, Seung Hyeok Han, Frank Chinga, Katalin Susztak   +5 more
doaj   +1 more source