Results 131 to 140 of about 2,757,661 (328)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Development and Implementation of a Dynamically Updated Big Data Intelligence Platform Using Electronic Medical Records for Secondary Hypertension

Reviews in Cardiovascular Medicine
Background: The accurate identification and diagnosis of secondary hypertension is critical,especially while cardiovascular heart disease continues to be the leading cause of death.
Nanfang Li, Qing Zhu, Yujie Dang, Yin Zhou, Xintian Cai, Mulalibieke Heizhati, Delian Zhang, Xiaoguang Yao, Qin Luo, Junli Hu, Guoliang Wang, Yingchun Wang, Menghui Wang, Jing Hong   +13 more
doaj   +1 more source

Clinical effectiveness and safety of amlodipine/losartan‐based single‐pill combination therapy in patients with hypertension: Findings from real‐world, multicenter observational databases

, 2021
Jieun Lee, Jaeyun Choi, Yunjin Yum, Hyung Joon Joo, Yong‐Hyun Kim, Hyonggin An, Eung Ju Kim   +6 more
openalex   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Polymorphisms in the WNK1 gene are asociated with blood pressure variation and urinary potassium excretion [PDF]

, 2009
WNK1 - a serine/threonine kinase involved in electrolyte homeostasis and blood pressure (BP) control - is an excellent candidate gene for essential hypertension (EH). We and others have previously reported association between WNK1 and BP variation. Using
Brown, M, Brunner, E, Burke, B, Cappucio, FP, Caulfield, M, Chambers, J, Clarke, R, Collins, R, Connell, JM, Dobson, R, Dominiczak, AF, Elliott, P, Eyheramendy, S, Farrall, M, Hoti, M, Howard, P, Iacone, R, Ji, C, Juhanson, P, Kooner, J, Kumari, M, Laan, M, Lathrop, GM, Lee, K, Marmot, M, Munroe, PB, Newhouse, S, Onipinla, A, Org, E, Samani, NJ, Shaw-Hawkins, S, Strazzullo, P, Veldre, G, Viigimaa, M, Wallace, C   +34 more
core  

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

Arthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

Atrial septal defect repair after a 10-month treatment with bosentan in a patient with severe pulmonary arterial hypertension: A case report [PDF]

, 2008
Konrad Höetzenecker, Hendrik Jan Ankersmit, Diana Bonderman, Wolfram Hoetzenecker, R. Seitelberger, Walter Klepetko, Iréne Lang   +6 more
openalex   +1 more source

Hydroxychloroquine Associated With Lower Glomerular Filtration Rate Decline in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical.
Shivani Garg, Brad Rovin, Brad C. Astor, Tripti Singh, Fauzia Hollnagel, Megan Kuik, Lexie Kolton, Callie Saric, S. Sam Lim, Christie M. Bartels   +9 more
wiley   +1 more source

Frailty progression before and after diabetes onset among older adults in china: a nationwide cohort study

BMC Geriatrics
Background Although epidemiological studies have established a link between diabetes and frailty, the dynamic changes in frailty before and after diabetes diagnosis remained inadequately characterized.
Ruomei Yang, Fang Sun, Zongming Yang, Zhencheng Yan, Zhigang Zhao, Hongbo He, Zhiming Zhu   +6 more
doaj   +1 more source

The effect of inhaled nitric oxide and inhaled iloprost on hypoxaemia in a patient with pulmonary hypertension after pulmonary thrombarterectomy [PDF]

, 2006
Michael Flondor, Olivia M. Merkel, Christian Hofstetter, Michael Irlbeck, L. Frey, Bernhard Zwißler   +5 more
openalex   +1 more source