Results 71 to 80 of about 3,374,250 (258)

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Estimation of the temperature field in laser-induced hyperthermia experiments with a phantom [PDF]

, 2018
Background: One of the challenges faced during the hyperthermia treatment of cancer is to monitor the temperature distribution in the region of interest. The main objective of this work was to accurately estimate the transient temperature distribution in
Lamien, Bernard, Eliçabe, Guillermo Enrique, Cotta, Renato Machado, Santos, Dilson Silva dos, Basto, Rodrigo Leite Queiroga, Varón, Leonardo Antonio Bermeo, Orlande, Helcio Rangel Barreto   +6 more
core   +1 more source

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

Advanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou, Caixi Yu, Guilan Xu, Lijuan Liu, Yujia Liang, Yulin Liang, He Ding, Litu Zhang, Piaoping Yang, Chen Wang   +9 more
wiley   +1 more source

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

Advanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li, Nana Zhang, Zexin Bian, Baobao Geng, Liyun Cao, Peipei Liu, Zengming Li, Yan Zhao, Jun Tan   +8 more
wiley   +1 more source

Short-time focused ultrasound hyperthermia enhances liposomal doxorubicin delivery and antitumor efficacy for brain metastasis of breast cancer

, 2017
The blood-brain/tumor barrier inhibits the uptake and accumulation of chemotherapeutic drugs. Hyperthermia can enhance the delivery of chemotherapeutic agent into tumors.
Wu, Sheng-Kai;Chiang, Chi-Feng;Hsu, Yu-Hone;Lin, Tzu-Hung;Liou, Houng-Chi;Fu, Wen-Mei;Lin, Win-Li, 林文澧;符文美   +1 more
core   +1 more source

Laser and radiofrequency-induced hyperthermia treatment via gold-coated magnetic nanocomposites [PDF]

, 2011
Alsayed AM Elsherbini1, Mahmoud Saber2, Mohamed Aggag2, Ahmed El-Shahawy2, Hesham AA Shokier11National Institute of Laser Enhanced Science, 2Children's Cancer Hospital, Cairo, EgyptIntroduction: The current radiofrequency ablation technique ...
Saber M, El-Shahawy A, Aggag M, Elsayed Elsherbini, Elsherbini AAM, Shokier HAA   +5 more
core   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Hyperthermia as a Therapeutic Agent

Journal of Rawalpindi Medical College, 2015
Background: To assess cell death inducing properties of hyperthermia on eye lids of full term Sprague- Dawley rats. Methods: An experimental study was carried out on eyelid of 64 full term Sprague-Dawley rats divided into a control group (A) and an ...
Nabeela Akhtar
doaj  

Motor performance is preserved in healthy aged adults following severe whole-body hyperthermia

International Journal of Hyperthermia, 2019
Healthy aging is associated with a progressive decline in motor performance and thermoregulatory efficiency. Functional consequences of severe whole-body hyperthermia on neurophysiological functions in healthy aged men have not been investigated.
Marius Brazaitis, Henrikas Paulauskas, Nerijus Eimantas, Laura Daniuseviciute, Gintautas Volungevicius, Albertas Skurvydas   +5 more
doaj   +1 more source

Mudanças de temperatura corporal induzidas por estresse em pombos (Columba Livia) [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2014Mudanças na Temperatura corporal (Tc) são consequências fisiológicas significativas induzidas ...
Bittencourt, Myla de Aguiar
core