Results 1 to 10 of about 64,766 (258)

Recent advances in preclinical studies combining hyperthermia therapy with novel immune checkpoint targeting agents [PDF]

open access: yesFrontiers in Immunology
Hyperthermia has been used as an adjuvant therapy alongside radiotherapy and chemotherapy for cancer treatment in some countries. However, since the 2000s, growing evidence has indicated that hyperthermia exerts regulatory effects not only on cancer ...
Na Li   +12 more
doaj   +2 more sources

Malignant Hyperthermia in Slavonic cohort – clinical and genetic findings beyond standard diagnostics [PDF]

open access: yesOrphanet Journal of Rare Diseases
Background Malignant Hyperthermia (MH) is a rare, hereditary, life-threatening pharmacogenetic disorder. The genetic background of MH was identified only in approximately half of MH-susceptible (MHS) patients, differing between geographical areas ...
Martina Klincová   +11 more
doaj   +2 more sources

Exploiting the dynamics of hyperthermia-enhanced delivery of thermosensitive liposomal doxorubicin to solid tumors [PDF]

open access: yesDrug Delivery
Thermosensitive liposomal (TSL) drug delivery with intravascular release under hyperthermia is a promising approach for chemotherapy of solid tumors, where the hyperthermia schedule strongly influences delivery efficacy.
Pouya Namakshenas   +2 more
doaj   +2 more sources

Simulation guided design of the MRcollar: a MR compatible applicator for deep heating in the head and neck region

open access: yesInternational Journal of Hyperthermia, 2021
Purpose To develop a head and neck hyperthermia phased array system compatible with a 1.5 T magnetic resonance (MR) scanner for noninvasive thermometry.
Tomas Drizdal   +7 more
doaj   +1 more source

Impact of a digital manual for guidance on malignant hyperthermia: patient education

open access: yesOrphanet Journal of Rare Diseases, 2022
Background Malignant hyperthermia (MH) is a rare, hereditary disease with a hypermetabolic response to volatile anesthetics/succinylcholine. Susceptible patients face difficulties due to a lack of knowledge about MH.
Gislene Rodrigues   +4 more
doaj   +1 more source

Malignant Hyperthermia in PICU—From Diagnosis to Treatment in the Light of Up-to-Date Knowledge

open access: yesChildren, 2022
Malignant Hyperthermia (MH) is a rare, hereditary, life-threatening disease triggered by volatile anesthetics and succinylcholine. Rarely, MH can occur after non-pharmacological triggers too. MH was detected more often in children and young adults, which
Martina Klincová   +4 more
doaj   +1 more source

Standardization of patient modeling in hyperthermia simulation studies: introducing the Erasmus Virtual Patient Repository

open access: yesInternational Journal of Hyperthermia, 2020
Purpose Thermal dose-effect relations have demonstrated that clinical effectiveness of hyperthermia would benefit from more controlled heating of the tumor.
Gennaro G. Bellizzi   +7 more
doaj   +1 more source

DnaJA4 is involved in responses to hyperthermia by regulating the expression of F-actin in HaCaT cells

open access: yesChinese Medical Journal, 2021
. Background. Hyperthermia in combination with DnaJA4-knockout (KO) obviously affects the anti-viral immunity of HaCaT cells. The mechanisms of this process are not yet fully explored.
Rui-Jiao Liu   +6 more
doaj   +1 more source

Focused ultrasound restrains the growth of orthotopic colon cancer via promoting pyroptosis

open access: yesFolia Histochemica et Cytobiologica, 2023
INTRODUCTION: Focused ultrasound (FUS) is a non-invasive tumor therapy technology emerging in recent years, which can treat various solid tumors. However, it is unclear whether FUS can affect the pyroptosis of colon cancer (CC) cells.
Weixing Mo   +8 more
doaj   +1 more source

Hyperthermia promotes exosome secretion by regulating Rab7b while increasing drug sensitivity in adriamycin-resistant breast cancer

open access: yesInternational Journal of Hyperthermia, 2022
Purpose To investigate the mechanism through which hyperthermia promotes exosome secretion and drug sensitivity in adriamycin-resistant breast cancer.
Di Xu   +9 more
doaj   +1 more source

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