Recent advances in preclinical studies combining hyperthermia therapy with novel immune checkpoint targeting agents [PDF]
Frontiers in ImmunologyHyperthermia has been used as an adjuvant therapy alongside radiotherapy and chemotherapy for cancer treatment in some countries. However, since the 2000s, growing evidence has indicated that hyperthermia exerts regulatory effects not only on cancer ...
Na Li +12 more
doaj +2 more sources
Malignant Hyperthermia in Slavonic cohort – clinical and genetic findings beyond standard diagnostics [PDF]
Orphanet Journal of Rare DiseasesBackground Malignant Hyperthermia (MH) is a rare, hereditary, life-threatening pharmacogenetic disorder. The genetic background of MH was identified only in approximately half of MH-susceptible (MHS) patients, differing between geographical areas ...
Martina Klincová +11 more
doaj +2 more sources
Exploiting the dynamics of hyperthermia-enhanced delivery of thermosensitive liposomal doxorubicin to solid tumors [PDF]
Drug DeliveryThermosensitive liposomal (TSL) drug delivery with intravascular release under hyperthermia is a promising approach for chemotherapy of solid tumors, where the hyperthermia schedule strongly influences delivery efficacy.
Pouya Namakshenas +2 more
doaj +2 more sources
Hyperthermia-targeted rectal delivery of thermosensitive liposomal doxorubicin via intra-arterial and intravenous administration [PDF]
Frontiers in PharmacologyIntroductionLyso-thermosensitive liposomal doxorubicin (LTLD) is a thermosensitive nanomedicine designed to release doxorubicin rapidly at mild hyperthermic temperatures.
Andrew S. Mikhail +12 more
doaj +2 more sources
Swiss Medical Weekly, 2012 Malignant hyperthermia (MH) is a subclinical myopathy, usually triggered by volatile anaesthetics and depolarising muscle relaxants. Clinical symptoms are variable, and the condition is sometimes difficult to identify. Nevertheless, rapid recognition and specific as well as symptomatic treatment are crucial to avoid a lethal outcome.
Bandschapp, O., Girard, T.
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International Journal of Hyperthermia, 2021 Purpose To develop a head and neck hyperthermia phased array system compatible with a 1.5 T magnetic resonance (MR) scanner for noninvasive thermometry.
Tomas Drizdal +7 more
doaj +1 more source
Impact of a digital manual for guidance on malignant hyperthermia: patient education
Orphanet Journal of Rare Diseases, 2022 Background Malignant hyperthermia (MH) is a rare, hereditary disease with a hypermetabolic response to volatile anesthetics/succinylcholine. Susceptible patients face difficulties due to a lack of knowledge about MH.
Gislene Rodrigues +4 more
doaj +1 more source
Malignant Hyperthermia in PICU—From Diagnosis to Treatment in the Light of Up-to-Date Knowledge
Children, 2022 Malignant Hyperthermia (MH) is a rare, hereditary, life-threatening disease triggered by volatile anesthetics and succinylcholine. Rarely, MH can occur after non-pharmacological triggers too. MH was detected more often in children and young adults, which
Martina Klincová +4 more
doaj +1 more source
Local hyperthermia with built-in endoscopy for radioresistant cervical cancer: a case series [PDF]
, 2023 We evaluated the efficacy and safety of an endoscope-embedded transvaginal laser hyperthermia system for superficial cervical cancer that remained in the cervix after radiotherapy.
Kajiyama, Hiroaki +6 more
core +1 more source
International Journal of Hyperthermia, 2020 Purpose Thermal dose-effect relations have demonstrated that clinical effectiveness of hyperthermia would benefit from more controlled heating of the tumor.
Gennaro G. Bellizzi +7 more
doaj +1 more source