Results 11 to 20 of about 64,766 (258)

Malignant hyperthermia [PDF]

open access: yesPostgraduate Medical Journal, 1998
SummaryMalignant hyperthermia is a rare autosomal dominant trait that predisposes affected individuals to great danger when exposed to certain anaesthetic triggering agents (such as potent volatile anaesthetics and succinylcholine). A sudden hypermetabolic reaction in skeletal muscle leading to hyperthermia and massive rhabdomyolysis can occur.
R, Ben Abraham   +3 more
openaire   +4 more sources

Malignant hyperthermia

open access: yesSwiss Medical Weekly, 2012
Malignant hyperthermia (MH) is a subclinical myopathy, usually triggered by volatile anaesthetics and depolarising muscle relaxants. Clinical symptoms are variable, and the condition is sometimes difficult to identify. Nevertheless, rapid recognition and specific as well as symptomatic treatment are crucial to avoid a lethal outcome.
Bandschapp, O., Girard, T.
openaire   +7 more sources

Hyperthermia promotes M1 polarization of macrophages via exosome-mediated HSPB8 transfer in triple negative breast cancer

open access: yesDiscover Oncology, 2023
Purpose To investigate the mechanism underlying the modulation of M1 macrophage polarization by exosomes released from hyperthermia-treated triple-negative breast cancer (TNBC) cells.
Di Xu   +8 more
doaj   +1 more source

Hyperthermia inhibits cellular function and induces immunogenic cell death in renal cell carcinoma

open access: yesBMC Cancer, 2023
Background In recent years, hyperthermia has been widely applied as a novel strategy for cancer treatment due to its multiple antitumour effects. In particular, the potential influences of hyperthermia on the tumour immune microenvironment may improve ...
Yin Huaqi   +8 more
doaj   +1 more source

Local Hyperthermia Versus Cryotherapy for Treatment of Plantar Warts: A Prospective Multi-centre Non-randomized Concurrent Controlled Clinical Trial

open access: yesActa Dermato-Venereologica, 2022
Cryotherapy is one of the most common treatments for warts; however, pain during treatment and relatively high recurrence rates limit its use. Local hyperthermia has also been used successfully in the treatment of plantar warts. The aim of this study was
Wei Huo   +20 more
doaj   +1 more source

Predictive value of SAR based quality indicators for head and neck hyperthermia treatment quality

open access: yesInternational Journal of Hyperthermia, 2019
Purpose: Hyperthermia treatment quality determines treatment effectiveness as shown by the clinically derived thermal-dose effect relations. SAR based optimization factors are used as possible surrogate for temperature, since they are not affected by ...
Gennaro G. Bellizzi   +5 more
doaj   +1 more source

Skeletal muscle microalterations in patients carrying Malignant Hyperthermia-related mutations of the e-c coupling machinery

open access: yesEuropean Journal of Translational Myology, 2016
We have compared the ultrastructure of skeletal muscle biopsies from patients that have survived a [Malignant Hyperthermia, MH] episode and siblings that test positive for MH susceptibility with those from siblings that tested negatives.
Manuela Lavorato   +3 more
doaj   +1 more source

The role of mitochondria-derived reactive oxygen species in hyperthermia-induced platelet apoptosis. [PDF]

open access: yesPLoS ONE, 2013
A combination of hyperthermia with radiotherapy and chemotherapy for various solid tumors has been practiced clinically. However, hyperthermic therapy has side effects, such as thrombocytopenia.
Zhicheng Wang   +5 more
doaj   +1 more source

Hyperthermia in oncology

open access: yesInternational Journal of Hyperthermia, 2001
The purpose of this article is to provide an overview on the current clinical application of hyperthermia combined with conventional treatment modalities (e.g. ionizing radiation, chemotherapy) in the treatment of malignant disease. The clinical application of hyperthermia with increase of tissue temperatures (range 40-44 degrees C) has been integrated
M H, Falk, R D, Issels
openaire   +2 more sources

Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers

open access: yesCell Reports, 2016
Even though hyperthermia is a promising treatment for cancer, the relationship between specific temperatures and clinical benefits and predictors of sensitivity of cancer to hyperthermia is poorly understood.
Hiroto Hatakeyama   +28 more
doaj   +1 more source

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