Results 21 to 30 of about 99,604 (303)

Predictive value of SAR based quality indicators for head and neck hyperthermia treatment quality

International Journal of Hyperthermia, 2019
Purpose: Hyperthermia treatment quality determines treatment effectiveness as shown by the clinically derived thermal-dose effect relations. SAR based optimization factors are used as possible surrogate for temperature, since they are not affected by ...
Gennaro G. Bellizzi, Tomas Drizdal, Gerard C. van Rhoon, Lorenzo Crocco, Tommaso Isernia, Margarethus M. Paulides   +5 more
doaj   +1 more source

Malignant hyperthermia [PDF]

Orphanet Journal of Rare Diseases, 2007
Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely, in humans, to stresses such as vigorous exercise and heat.
Pollock Neil, James Danielle, Davis Mark, Rosenberg Henry, Stowell Kathryn   +4 more
openaire   +3 more sources

Quality assurance guidelines for interstitial hyperthermia [PDF]

, 2019
Quality assurance (QA) guidelines are essential to provide uniform execution of clinical hyperthermia treatments and trials. This document outlines the clinical and technical consequences of the specific properties of interstitial heat delivery and ...
Stauffer, P. R., Crezee, J., Van Rhoon, G. C., Strnad, V.,, Kukiełka, A. M., Hurwitz, M. D., Abdel-Rahman, S.,, Schmidt, M.,, Ghadjar, Pirus, Strnad, V., Kok, H. P.,, Gordeyev, S. S.,, Abdel-Rahman, S, Nadobny, J., Diederich, C. J., Ghadjar, P., Lamprecht, U.,, Ghadjar, Pirus,, Schmidt, M., Kok, H. P., Nadobny, J.,, Gordeyev, S. S., Marder, D., Vujaskovic, Z., Dobšíček Trefná, H., Van Rhoon, G. C.,, Abdel-Rahman, S., Dobsicek Trefna, Hana,, Lamprecht, U., Dobsicek Trefna, Hana, Kukiełka, A. M.,, Vujaskovic, Z.,, Stauffer, P. R.,, Diederich, C. J.,, Crezee, J.,, Marder, D.,, Hurwitz, M. D.,   +36 more
core   +1 more source

Skeletal muscle microalterations in patients carrying Malignant Hyperthermia-related mutations of the e-c coupling machinery

European Journal of Translational Myology, 2016
We have compared the ultrastructure of skeletal muscle biopsies from patients that have survived a [Malignant Hyperthermia, MH] episode and siblings that test positive for MH susceptibility with those from siblings that tested negatives.
Manuela Lavorato, Pawan K. Gupta, Philip M. Hopkins, Clara Franzini-Armstrong   +3 more
doaj   +1 more source

Functional effects of mutations in the skeletal muscle ryanodine receptor type 1 (RYR1) linked to malignant hyperthermia and central core disease [PDF]

, 2006
Malignant hyperthermia (MH) is a pharmacogenetic disorder with autosomal dominant inheritance. In susceptible individuals, a MH crisis may be triggered by commonly used halogenated anaesthetics (halothane, isoflurane) or muscle relaxants ...
Ducreux, Sylvie
core   +1 more source

The role of mitochondria-derived reactive oxygen species in hyperthermia-induced platelet apoptosis. [PDF]

PLoS ONE, 2013
A combination of hyperthermia with radiotherapy and chemotherapy for various solid tumors has been practiced clinically. However, hyperthermic therapy has side effects, such as thrombocytopenia.
Zhicheng Wang, Feng Cai, Xiaoyu Chen, Meihong Luo, Lingling Hu, Yuan Lu   +5 more
doaj   +1 more source

LOCAL HYPERTHERMIA IN THE TREATMNET OF LOCALLY ADVANCED CERVICAL CANCER: CURRENT VIEW ON THE PROBLEM

Сибирский онкологический журнал, 2021
The purpose of the study was to review available data on the combined use of local hyperthermia and chemotherapy/radiotherapy in the treatment of locally advanced cervical cancer, as well as to analyze longterm treatment outcomes.Material and methods.
O. V. Shpileva, L. A. Kolomiets, Zh. A. Startseva, O. N. Churuksaeva   +3 more
doaj   +1 more source

Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers

Cell Reports, 2016
Even though hyperthermia is a promising treatment for cancer, the relationship between specific temperatures and clinical benefits and predictors of sensitivity of cancer to hyperthermia is poorly understood.
Hiroto Hatakeyama, Sherry Y. Wu, Yasmin A. Lyons, Sunila Pradeep, Wanqin Wang, Qian Huang, Karem A. Court, Tao Liu, Song Nie, Cristian Rodriguez-Aguayo, Fangrong Shen, Yan Huang, Takeshi Hisamatsu, Takashi Mitamura, Nicholas Jennings, Jeajun Shim, Piotr L. Dorniak, Lingegowda S. Mangala, Marco Petrillo, Vladislav A. Petyuk, Athena A. Schepmoes, Anil K. Shukla, Madeline Torres-Lugo, Ju-Seog Lee, Karin D. Rodland, Anna Fagotti, Gabriel Lopez-Berestein, Chun Li, Anil K. Sood   +28 more
doaj   +1 more source

Multipotent mesenchymal stromal cells are sensitive to thermic stress – potential implications for therapeutic hyperthermia

International Journal of Hyperthermia, 2020
Purpose Hyperthermia demonstrated clinical efficacy in multimodal cancer treatment. Multipotent mesenchymal stromal cells (MSCs) as part of the tumor-supporting stroma modulate tumor response and tissue regeneration after hyperthermia.
Alexander Rühle, Andreas Thomsen, Rainer Saffrich, Maren Voglstätter, Birgit Bieber, Tanja Sprave, Patrick Wuchter, Peter Vaupel, Peter E. Huber, Anca-Ligia Grosu, Nils H. Nicolay   +10 more
doaj   +1 more source

Hyperthermia in oncology

International Journal of Hyperthermia, 2001
The purpose of this article is to provide an overview on the current clinical application of hyperthermia combined with conventional treatment modalities (e.g. ionizing radiation, chemotherapy) in the treatment of malignant disease. The clinical application of hyperthermia with increase of tissue temperatures (range 40-44 degrees C) has been integrated
M H, Falk, R D, Issels
openaire   +2 more sources