Results 41 to 50 of about 99,604 (303)

Berberine Chloride and Hyperthermia Promote Osterix Expression and Suppress Cell Cycle Genes in Osteosarcoma Cells

Yemeni Journal for Medical Sciences, 2018
Objectives: The aim of the current study was to investigate the effects of berberine chloride and various heat conditions on the gene expression of Osterix, RUNX-2, RANKL, CDK2, CDK4, IL-6 and IL-11.
Mohammed Ali Nashiry, Alyaa R Rajih AL-Khateeb, Gabriele Froemming   +2 more
doaj   +1 more source

Analysis of clinical data to determine the minimum number of sensors required for adequate skin temperature monitoring of superficial hyperthermia treatments [PDF]

, 2018
Purpose: Tumor response and treatment toxicity are related to minimum and maximum tissue temperatures during hyperthermia, respectively. Using a large set of clinical data, we analyzed the number of sensors required to adequately monitor skin temperature
Crezee, H., Stauffer, P. R., Bakker, A.,, Bakker, A., Dario B. Rodrigues, van Tienhoven, Geertjan,, Akke Bakker, Tienhoven, G. van, Dobšíček Trefná, Hana, Bakker, Akke, Rasch, C.R.N., Holman, Rebecca, Coen R. N. Rasch, Rasch, Coen R.N.,, Rasch, Coen R.N., Rodrigues, D.B., Holman, Rebecca,, Hans Crezee, Trefna, H.D., Paul R. Stauffer, Stauffer, Paul R., Crezee, Hans, Geertjan van Tienhoven, Rodrigues, Dario B.,, Holman, R., Rasch, Coen R. N., Hana Dobšíček Trefná, Dobsicek Trefna, Hana,, Stauffer, P.R., Rodrigues, Dario B., Rebecca Holman, Stauffer, P. R.,, van Tienhoven, Geertjan, Crezee, Hans,   +33 more
core   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Malignant Hyperthermia in Slavonic cohort – clinical and genetic findings beyond standard diagnostics

Orphanet Journal of Rare Diseases
Background Malignant Hyperthermia (MH) is a rare, hereditary, life-threatening pharmacogenetic disorder. The genetic background of MH was identified only in approximately half of MH-susceptible (MHS) patients, differing between geographical areas ...
Martina Klincová, Jana Zídková, Kamila Réblová, Dagmar Štěpánková, Ivana Schröderová, Renata Gaillyová, Tereza Bönischová, Natálie Havránková, Veronika Tomášková, Tereza Kramářová, Lenka Fajkusová, Petr Štourač   +11 more
doaj   +1 more source

Recent advances in preclinical studies combining hyperthermia therapy with novel immune checkpoint targeting agents

Frontiers in Immunology
Hyperthermia has been used as an adjuvant therapy alongside radiotherapy and chemotherapy for cancer treatment in some countries. However, since the 2000s, growing evidence has indicated that hyperthermia exerts regulatory effects not only on cancer ...
Na Li, Na Li, Na Li, Jian Yu, Jian Yu, Jian Yu, Jian Yu, Ruoyu Wang, Ruoyu Wang, Ruoyu Wang, Ruoyu Wang, Guanyu Gong, Guanyu Gong   +12 more
doaj   +1 more source

Investigation of energy metabolic dynamism in hyperthermia-resistant ovarian and uterine cancer cells under heat stress

Scientific Reports, 2021
Despite progress in the use of hyperthermia in clinical practice, the thermosensitivity of cancer cells is poorly understood. In a previous study, we found that sensitivity to hyperthermia varied between ovarian and uterine cancer cell lines.
Taisei Kanamori, Natumi Miyazaki, Shigeki Aoki, Kousei Ito, Akihiro Hisaka, Hiroto Hatakeyama   +5 more
doaj   +1 more source

Acute postoperative sepsis mimicking symptomology suspicious for malignant hyperthermia: case report [PDF]

Revista Brasileira de Anestesiologia, 2020
Background: Sepsis is a life-threatening organ dysfunction with non-specific clinical features that can mimic other clinical conditions with hyper metabolic state such as malignant hyperthermia.
Vendhan Ramanujam, Christopher R. Hoffman, Kevin Russo, Michael S. Green   +3 more
doaj   +3 more sources

Membrane‐Bound Multimodal Plasmonic Transducers for Noninvasive, In Situ Monitoring and Control of CAR T Cells Against Heterogeneous Solid Tumors

Advanced Materials, EarlyView.
Membrane‐bound multimodal transducers enable longitudinal ultrasound‐guided photoacoustic monitoring and in situ thermal control of CAR T cells in heterogeneous solid tumors. Imaging correlates T cell trafficking with tumor response, distinguishing responders from nonresponders.
Myeongsoo Kim, Ali Zamat, Melissa Cadena, Chloé Thiveaud, Riya Sen, Jeungyoon Lee, Elif Kulaksizoglu, S. Abbey Oliver, Don VanderLaan, Sydney Fábrega, Zizhen Zha, Kelsey P. Kubelick, Jinhwan Kim, Gabriel A. Kwong, Stanislav Y. Emelianov   +14 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Modification of thermosensitivity and chemosensitivity induced by combined treatments with hyperthermia and adriamycin [PDF]

, 2001
Both adriamycin (ADM) and hyperthermia show thermal chemo-enhancement. Tolerance induction against ADM in heated cells has been reported resulting in clinical difficulty of cancer therapy.
Hayashi, Sachiko, Hatashita, Masanori, Tsuji, Koh, Jin, Zhao-Hui, Furukawa-Furuya, Masayo, Matsumoto, Hideki, Kano, Eiichi, Ohtsubo, Toshio, Yoshikawa, Shinji, Kitai, Ryuhei   +9 more
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