Results 61 to 70 of about 171,666 (338)

Osmolality Selectively Offsets the Impact of Hyperthermia on Mouse Skeletal Muscle in vitro

open access: yesFrontiers in Physiology, 2018
Hyperthermia and dehydration can occur during exercise in hot environments. Nevertheless, whether elevations in extracellular osmolality contributes to the increased skeletal muscle tension, sarcolemmal injury, and oxidative stress reported in warm ...
Orlando Laitano   +6 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Prevalence of malignant hyperthermia diagnosis in obstetric patients in the United States, 2003 to 2014

open access: yesBMC Anesthesiology, 2020
Background The cost-benefit of stocking dantrolene in maternity units for treating malignant hyperthermia (MH) has been recently questioned because of the low incidence of MH crisis in the general population and the low utilization of general anesthesia ...
Jean Guglielminotti   +2 more
doaj   +1 more source

Approaches for modeling magnetic nanoparticle dynamics

open access: yes, 2014
Magnetic nanoparticles are useful biological probes as well as therapeutic agents. There have been several approaches used to model nanoparticle magnetization dynamics for both Brownian as well as N\'eel rotation. The magnetizations are often of interest
Reeves, Daniel B., Weaver, John B.
core   +1 more source

Dehydration accelerates reductions in cerebral blood flow during prolonged exercise in the heat without compromising brain metabolism [PDF]

open access: yes, 2015
Dehydration hastens the decline in cerebral blood flow (CBF) during incremental exercise, while the cerebral metabolic rate for oxygen (CMRO2) is preserved.
Benjamin Garcia   +8 more
core   +2 more sources

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Sonodynamic therapy with chemo-radiotherapy in high-grade brainstem gliomas: A prospective phase IIa clinical trial

open access: yesPhotodiagnosis and Photodynamic Therapy
The treatment of high-grade brainstem gliomas (HBSGs), which are a type of malignant neoplasm, is challenging. There is a need to develop novel and effective therapeutic approaches for HBSGs. This study analyzed the data between sonodynamic therapy (SDT)
Xiaohao Liu   +9 more
doaj   +1 more source

Mild hyperthermia enhances sensitivity of gastric cancer cells to chemotherapy through reactive oxygen species–induced autophagic death

open access: yesTumor Biology, 2017
Mild hyperthermia enhances anti-cancer effects of chemotherapy, but the precise biochemical mechanisms involved are not clear. This study was carried out to investigate whether mild hyperthermia sensitizes gastric cancer cells to chemotherapy through ...
Ming-Chen Ba   +6 more
doaj   +1 more source

Multifunctional Nanoparticles for Imaging Guided Interventions [PDF]

open access: yes, 2008
We describe multifunctional magnetic nanoparticles (MNPs) encapsulated in thermosensitive, drug-bearing shells and delivered to the tumor site by genetically modified and non-pathogenic strains of bacteria with known affinity to tumors for an effective ...
Basel al-Ramadi   +5 more
core   +1 more source

3D Anodic Alumina Nanoarchitectures: A Decade of Progress from Foundational Science to Functional Metamaterials

open access: yesAdvanced Materials, EarlyView.
Ordered three‐dimensional anodic aluminum oxide (3D‐AAO) nanoarchitectures with longitudinal and transverse pores enable architecture‐driven metamaterials. The review maps fabrication advances, including hybrid pulse anodization, and shows how 3D‐AAO templates tailor properties across magnetism, energy, catalysis, and sensing.
Marisol Martín‐González
wiley   +1 more source

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