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Anesthesia for Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
2021HIPEC is a highly concentrated, heated chemotherapy treatment that is delivered directly into the abdominal cavity after cytoreductive surgery (CRS). Anesthetic management for Cytoreductive surgery (CRS) with HIPEC (hyperthermic intraperitoneal chemotherapy) involves multiple challenges including the patient’s preoperative health status, disease load ...
Sanne H. Hidding+2 more
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Laparoscopic hyperthermic intraperitoneal chemotherapy for appendiceal tumors
Asian Journal of Endoscopic Surgery, 2020AbstractIntroductionThe application of hyperthermic intraperitoneal chemotherapy (HIPEC) in colorectal and appendix cancer at risk of peritoneal seeding is an appealing strategy to prevent peritoneal metastases. Here, we present the technical details and postoperative outcomes of laparoscopic HIPEC performed with prophylactic intent in three patients ...
Antonio Sommariva+5 more
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Intraperitoneal and Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Ovarian Cancer
Current Treatment Options in OncologyIn our clinical practice, we have shifted away from the use of adjuvant normothermic intraperitoneal (IP) chemotherapy, particularly following the publication of GOG 252. Our decision is rooted in the accumulating evidence indicating a lack of demonstrable superiority, alongside the recognized toxicities and logistical challenges associated with its ...
Joyce Y, Wang+3 more
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Scrotal Ulcer After Intraperitoneal Hyperthermic Chemotherapy
Urology, 2007Tumor cytoreduction combined with intraperitoneal hyperthermic chemotherapy has been shown to be an effective method to delay the progression of peritoneal carcinomatosis. We describe 2 cases of painful scrotal ulcer after tumor debulking and intraperitoneal infusion of mitomycin-C for treatment of metastatic abdominal malignancies.
Ming Yin+2 more
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Intraoperative fluid restriction in hyperthermic intraperitoneal chemotherapy
Journal of Surgical Research, 2018Multiple studies highlight the importance of liberal fluid administration in cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). Over-resuscitation can delay recovery and wound healing. We report an intraoperative protocol that restricts fluid administration and minimizes morbidity.Retrospective analysis of 35 patients ...
Tariq Almerey+3 more
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Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy [PDF]
Although uncommon, intra-abdominal neoplasms may spread when tumor cells seed the surrounding peritoneal surfaces. Although intraperitoneal dissemination of neoplastic cells represents a universally fatal problem that is difficult to treat, cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has emerged as a treatment ...
Perry Shen+4 more
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The approval process for hyperthermic intraoperative intraperitoneal chemotherapy
European Journal of Surgical Oncology (EJSO), 2006To clarify the requirements for Food and Drug Administration approval in the United States for hyperthermic intraoperative intraperitoneal chemotherapy administration. Also, to review the status of the approval process in Europe.The obstacles to be overcome for approval by the Food and Drug Administration for a new drug approval and for a new device ...
Paul H. Sugarbaker, L. Clarke
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Techniques of Delivering Hyperthermic Intraperitoneal Chemotherapy
2007Hyperthermic intraperitoneal chemotherapy (HIPEC) was first delivered to a human in 1979 by Dr. John Spratt at the University of Louisville when he treated a male patient with pseudomyxoma peritonei (1). In collaboration with other researchers, he developed a delivery system using a “closed” technique, with both the fascia and skin closed.
Paul H. Sugarbaker+2 more
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Hyperthermic Intraperitoneal Chemotherapy: An Overview #412
Journal of Palliative Medicine, 2021Oliver S. Eng, Ryan B. Morgan, Sandy Tun
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Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
BJA Education, 2021J Bell, L Boss, S Durnford
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