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The Role of Hypertonic Saline in Neurosurgery
World Neurosurgery, 2014he first reported experiments with hypertonic saline (HS) were performed in 1919 whereby intravenous injections T of 30% sodium chloride or saturated sodium bicarbonate were found to result in marked decrease in brain size and intracranial pressure (22).
Robert M, Starke, Aaron S, Dumont
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The role of hypertonic saline in neurotrauma
European Journal of Anaesthesiology, 2008Animal and human studies suggest that hypertonic saline is a potential therapeutic agent to assist with the medical treatment of patients with traumatic brain injury. It may have a place as osmotherapy to decrease brain size, predominantly of uninjured brain and has several potential advantages over mannitol.
White, H., Cook, D., Venkatesh, B.
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Hypertonic saline: a clinical review
Neurosurgical Review, 2007Literature suggest that hypertonic saline (HTS) solution with sodium chloride concentration greater than the physiologic 0.9% can be useful in controlling elevated intracranial pressure (ICP) and as a resuscitative agent in multiple settings including traumatic brain injury (TBI).
R, Tyagi +3 more
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Hypertonic Saline Induction of Abortion
JAMA: The Journal of the American Medical Association, 1970To the Editor.— I must disagree with Manabe's condemnation of hypertonic saline for the induction of abortion ( 210: 2091, 1969). As he states, there were reports of deaths occurring in Japan after World War II following the intra-amniotic administration of saline, but because of the lack of specific details in the reports, the English-reading ...
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The Effect of Oxytocin on Hypertonic Saline Abortion
Acta Obstetricia et Gynecologica Scandinavica, 1977Abstract. Oxytocin was infused in 22 randomly selected pregnant women after extraamniotic hypertonic saline instillation. In another 24 pregnant women no oxytocin was infused at midtrimester abortion. There was no difference between the two groups in mean time from saline injection to expulsion of the fetus.
B, Sandström, F, Solheim, S, Magnusson
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INTRATHECAL ADMINISTRATION OF HYPERTONIC SALINE
Neurosurgery, 1988M H, Savitz, L I, Malis
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Hypertonic Saline Instillation
1981Instillation of hypertonic saline (20% NaCl) into the amniotic sac was one of the first methods used in this country to perform legal abortion by amnioinfusion. Even today, it probably is the most widely used method for late second-trimester abortions. When performed by experienced physicians, amnioinfusion with hypertonic saline is an effective method
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