Results 171 to 180 of about 56,808 (268)

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Navigating hypertriglyceridemia in pregnancy: current evidence and clinical strategies. [PDF]

Front Endocrinol (Lausanne)
Chamerski S, Wartecka-Zielińska K, Pomorski F, Karos W, Marlęga-Linert J, Marcinkowska M, Stefańska K, Grzybowska M, Wydra D, Gruchała M, Mickiewicz A.   +10 more
europepmc   +1 more source

Metabolic Syndrome: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 9, September 2026.
A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley   +1 more source

Hypertriglyceridemia‑Induced Acute Pancreatitis Compared With Non-Hypertriglyceridemia Acute Pancreatitis: A Retrospective Case-Control Study. [PDF]

Health Sci Rep
Farhangiyan Z, Moradi L, Vaziri M, Lak E, Zaman F, Mohammadi S.   +5 more
europepmc   +1 more source

Differential Expression of Human and Bacterial Proteins Reveals Microbiome–Host Crosstalk in Metabolic Disorders

PROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.
ABSTRACT Purpose The growing prevalence of obesity, MetS, and T2DM highlights the need to better understand host–microbiota interactions. While gut microbiota has been widely investigated, interactions between the oral microbiota and human salivary proteins remain largely unexplored.
Carlos Vinicius Ferreira da Silva, Carlos José Ferreira da Silva, Fernanda da Silva Marinho, Youssef Bacila Sade, Sandra Mara Naressi Scapin, Fabiano L. Thompson, Cristiane Thompson, Eidy de Oliveira Santos   +7 more
wiley   +1 more source

Rhabdomyolysis and Acute Kidney Injury Associated With Acute Legionella Infection. [PDF]

Am J Case Rep
Deming RA, Fei M, McCaskey C, Schuurs R, Chin SF, Amadi I, Raj J.   +6 more
europepmc   +1 more source

Deciphering the Mechanisms of Statin–Ezetimibe Drug Combinations Using Boolean Logical Modeling and Transcriptomic Data

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Drug Combinations offer increased therapeutic efficacy and reduced toxicity compared with single agents. Understanding a drug combination's mechanisms of action (MoA) can provide important insights into therapeutic efficacy. The MoA of many FDA‐approved drugs, however, often remains unclear.
Rui‐Sheng Wang, Matteo Pedrelli, Osman Ahmed, Garagnani Paolo, Paolo Parini, Joseph Loscalzo   +5 more
wiley   +1 more source

Milky Blood in a Middle-Aged Man With Diabetes Mellitus: Familial Chylomicronemia Syndrome due to GPIHBP1 Mutation. [PDF]

Clin Case Rep
Sankhi MN, Bansal N, Samadarshi S, Singh SK, Vashisht R.   +4 more
europepmc   +1 more source

Multicomponent Analysis of Antihyperlipidemic Drugs: Integrating Analytical Quality by Design and Multi‐Metric Green Liquid Chromatography

SEPARATION SCIENCE PLUS, Volume 9, Issue 9, September 2026.
Robust HPLC method quantifies four antihyperlipidemic drugs. Central composite design optimized the analytical conditions. Achieved complete isocratic separation in under 10 min. Multiple green metrics confirmed excellent environmental sustainability. Validated method successfully analyzed commercial binary formulations.
Venkatesh Bukkapatnam, Raja Sundararajan
wiley   +1 more source

Current and Emerging Pharmacological Therapies for Hypertriglyceridemia. [PDF]

Int J Mol Sci
Alhomoud IS.
europepmc   +1 more source