Results 51 to 60 of about 85,025 (319)

Evaluation of the Therapeutic Potential of Bioactive Materials Based on a Complex of Oxidovanadium(IV) and Exopolysaccharide Levan in a Model of Insulin Resistance in Mice

ChemMedChem, EarlyView.
A low‐toxicity bioactive composition of oxidovanadium(IV) and exopolysaccharide levan is synthesized, characterized, and shown to reduce hyperglycemia, hypertriglyceridemia, and TyG index in a mice model of dexamethasone‐induced insulin resistance. Bioactive compositions containing vanadium complexes have been a viable strategy for constructing more ...
Amanda K. J. P. F. da Silva, Eucilene K. de L. B. Marques, Lidiane M. A. de Lima, Widarlane A. S. Alves, Dayane A. Gomes, Pedro L. Guzzo, Mônica F. Belian, Wagner E. Silva, Eduardo C. Lira   +8 more
wiley   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye, Rui Zhang, Jing Wan, Jinping Zhou, Pengpeng Guo, Dianwen Yu, Peixia Li, Yani Liu, Shaojun Shi   +8 more
wiley   +1 more source

Identification of hypertriglyceridemia based on bone density, body fat mass, and anthropometry in a Korean population

BMC Cardiovascular Disorders, 2019
Background Hypertriglyceridemia is strongly associated with the risks of cardiovascular disease, coronary heart disease, and metabolic syndrome. The relationship between hypertriglyceridemia or high triglyceride levels and bone mineral density remains ...
Jeong Hee Chi, Moon Sun Shin, Bum Ju Lee
doaj   +1 more source

Association of hypertension and hypertriglyceridemia on incident hyperuricemia: an 8-year prospective cohort study

Journal of Translational Medicine, 2020
Background Hypertension and high triglyceride are two of the most important risk factors for hyperuricemia. Epidemiological records show that hypertension and dyslipidemia often coexist and may significantly increase the risk of target organ damage ...
Yuan Zhang, Miaomiao Zhang, Xiawen Yu, Fengjiang Wei, Chen Chen, Kai Zhang, Shuzhi Feng, Yaogang Wang, Wei-Dong Li   +8 more
doaj   +1 more source

Variety of clinical manifestations of hypertriglyceridemia: a case series

Российский кардиологический журнал, 2023
To date, there is no doubt about the participation of triglyceride-rich lipoproteins in atherogenesis. However, the variety of clinical manifestations of hypertriglyceridemia does not always allow timely recognition of patients with high cardiovascular ...
V. K. Zafiraki, A. M. Namitokov, I. V. Gilevich, M. V. Gradovskaya, O. V. Malyarevskaya, K. V. Karabakhtsieva   +5 more
doaj   +1 more source

Therapy of Canine Hyperlipidemia with Bezafibrate. [PDF]

, 2017
BackgroundBezafibrate (BZF) is effective in the treatment of hypertriglyceridemia in human patients, but there are no data on its use in dogs.ObjectiveTo assess the safety of BZF in hyperlipidemic dogs and its efficacy in decreasing serum triglyceride ...
Casado, TC, De Marco, V, Florio, JC, Gilor, C, Nakandakare, ER, Noronha, KSM, Santos, EZ   +6 more
core   +1 more source

Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia

Journal of Lipid Research, 1983
Plasma lipoprotein concentration, composition, and size were evaluated in two common familial forms of hypertriglyceridemia and compared with those in normal subjects.
J D Brunzell, J J Albers, A Chait, S M Grundy, E Groszek, G B McDonald   +5 more
doaj   +1 more source

Impact of contraception and IVF hormones on metabolic, endocrine, and inflammatory status [PDF]

, 2020
Assisted reproductive technologies (ART) represent commonly utilized management strategies for infertility with multifactorial causes (including genetically predisposed diseases). Amongst ART, in vitro fertilization (IVF) is the most popular.
Barber, Thomas M., Coussa, Ayla, Hassan, Hayder   +2 more
core   +1 more source

Heparin and insulin in the management of hypertriglyceridemia-associated pancreatitis: case series and literature review

Archives of Endocrinology and Metabolism, 2017
SUMMARY Severe hypertriglyceridemia accounts for up to 7% of all cases of acute pancreatitis. Heparin and insulin activate lipoprotein lipase (LPL), thereby reducing plasma triglyceride levels.
Mohammad Shafi Kuchay, Khalid J. Farooqui, Tarannum Bano, Manoj Khandelwal, Harmandeep Gill, Ambrish Mithal   +5 more
doaj   +1 more source

Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients. [PDF]

, 2017
Hypertriglyceridemia is an independent risk factor for cardiovascular disease. Apolipoprotein C-II (APOC2) is an obligatory cofactor for lipoprotein lipase (LPL), the major enzyme catalyzing plasma triglyceride hydrolysis.
Gaudet, Daniel, Liu, Chao, Miller, Yury I   +2 more
core   +1 more source