Results 61 to 70 of about 49,127 (236)

PPARα Agonist Fenofibrate Reduced the Secreting Load of β-Cells in Hypertriglyceridemia Patients with Normal Glucose Tolerance

PPAR Research, 2016
Hypertriglyceridemia is an important risk factor associated with insulin resistance and β-cell dysfunction. This study investigated the effects of hypertriglyceridemia and fenofibrate treatment on insulin sensitivity and β-cell function in subjects with ...
Jia Liu, Rui Lu, Ying Wang, Yanjin Hu, Yumei Jia, Ning Yang, Jing Fu, Guang Wang   +7 more
doaj   +1 more source

Heparin and insulin in the management of hypertriglyceridemia-associated pancreatitis: case series and literature review

Archives of Endocrinology and Metabolism, 2017
SUMMARY Severe hypertriglyceridemia accounts for up to 7% of all cases of acute pancreatitis. Heparin and insulin activate lipoprotein lipase (LPL), thereby reducing plasma triglyceride levels.
Mohammad Shafi Kuchay, Khalid J. Farooqui, Tarannum Bano, Manoj Khandelwal, Harmandeep Gill, Ambrish Mithal   +5 more
doaj   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Dietary and lifestyle habits in patients with hypertriglyceridemia referred to a Danish lipid clinic: A retrospective cross-sectional and follow-up study

Clinical Nutrition Open Science
Background and aims: Dietary and lifestyle counseling represent the cornerstone of treatment of hypertriglyceridemia, but limited knowledge exists on the dietary habits among patients with severe and extremely elevated plasma triglycerides. In this study
Martin Nguyen, Katrine Rigmor Routhe Carlsen, Valdemar Holkenberg Andersen, Erik Berg Schmidt, Stine Krogh Venø, Christian Bork   +5 more
doaj   +1 more source

Use of Iatrogenic Lipid Emulsion and Subsequent Plasmapheresis for the Treatment of Amitriptyline Overdose

Case Reports in Critical Care, 2022
Plasmapheresis for the treatment of hypertriglyceridemia is relatively uncommon and mostly reported either in patients experiencing hypertriglyceridemia-induced acute pancreatitis or patients with therapy-resistant familial hypercholesterolemia. Standard
Ryan C. Laffin, Ashley M. Cunningham, Sean A. Fitzgerald, Donald A. Wiebe, Jeffrey A. Wells, Janice Robin Linzell, William Nicholas Rose   +6 more
doaj   +1 more source

Application of current enteral nutrition support recommendations to infants born less than 750 grams or less than 25 weeks' gestation: A critical review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Clinicians face a paucity of evidence‐based recommendations for provision of enteral nutrition in infants born <750 g or <25 weeks’ gestation, termed “nano‐preterm.” Current enteral nutrition recommendations for extremely low birth weight infants may not be broadly applicable to nano‐preterm infants due to physiological and developmental ...
Mar Romero‐Lopez, Mamta Naik, Teresa Hartman, Ann Anderson‐Berry, Melissa Thoene   +4 more
wiley   +1 more source

Clinical Diagnosis of Familial Hypertriglyceridemia-induced Recurrent Acute Pancreatitis at Rural Outreach Outpatient Department: a Case Report [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy
Acute pancreatitis is a common condition with significant morbidity and mortality. After gallstones and alcohol, hypertriglyceridemia is another important cause of recurrent acute pancreatitis.
Swasti Pathak, Nishant Kumar Malviya, Ankita Pathak, Ashutosh Pathak, Aparna Pathak, Ravindra Nath Pathak, Swati Tripathi, Ambuj Tripathi   +7 more
doaj   +1 more source

Association of periodontitis with incidence of metabolic syndrome in Korea: A retrospective cohort study

Journal of Periodontology, EarlyView.
Abstract Background Although periodontitis has been linked to systemic conditions such as metabolic syndrome, longitudinal evidence remains limited. This nationwide population‐based cohort study aimed to investigate whether periodontal status is associated with the incidence of metabolic syndrome in Korea.
SeoYeon Hwang, Hae‐Young Kim, Sangwook Kang, Junesun Kim, Sunmi Song, Gum‐Ryeong Park   +5 more
wiley   +1 more source

Hypertriglyceridemic Acute Pancreatitis With Concomitant Retrocecal Appendicitis: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Hypertriglyceridemia‐induced acute pancreatitis and acute appendicitis are distinct clinical conditions rarely reported to occur concurrently. We present a case of hypertriglyceridemia‐induced pancreatitis characterized by clinical deterioration despite a decline in serum triglyceride levels.
Esfahani MS, Shekarchizadeh M, Tabatabaei SAD, Tabatabaei MD.   +3 more
europepmc   +2 more sources

Tirzepatide use in adolescents with metabolic dysfunction‐associated steatotic liver disease (MASLD): A case series

JPGN Reports, EarlyView.
Abstract Pediatric obesity and metabolic dysfunction‐associated steatotic liver disease (MASLD) prevalence has risen markedly over the past decade. Due to transition delays and workforce shortages, pediatric specialists often manage patients into young adulthood, and thus familiarity with adult pharmacotherapies for MASLD is essential.
Brandon J. Perumpail, Andrea Tou, Jennifer Panganiban   +2 more
wiley   +1 more source