Results 61 to 70 of about 68,532 (268)

Heparin and insulin in the management of hypertriglyceridemia-associated pancreatitis: case series and literature review

Archives of Endocrinology and Metabolism, 2017
SUMMARY Severe hypertriglyceridemia accounts for up to 7% of all cases of acute pancreatitis. Heparin and insulin activate lipoprotein lipase (LPL), thereby reducing plasma triglyceride levels.
Mohammad Shafi Kuchay, Khalid J. Farooqui, Tarannum Bano, Manoj Khandelwal, Harmandeep Gill, Ambrish Mithal   +5 more
doaj   +1 more source

Low-Grade Inflammation in the Association between Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis: A Study of More Than 115000 Individuals from the General Population.

Clinical Chemistry, 2019
BACKGROUND How mild-to-moderate hypertriglyceridemia (2-10 mmol/L; 177-886 mg/dL) potentially causes acute pancreatitis is unknown; however, cellular studies indicate that inflammation might be a driver of disease progression.
Signe E. J. Hansen, C. M. Madsen, A. Varbo, B. Nordestgaard   +3 more
semanticscholar   +1 more source

High incidence of hypertriglyceridemia in a Brazilian cohort of people living with HIV/AIDS undergoing antiretroviral treatment in Belo Horizonte, 2001-2010

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Hypertriglyceridemia incidence should be estimated in HIV-infected patients after antiretroviral therapy (ART) initiation. METHODS: We retrospectively analyzed clinical data of HIV-infected adults at 3 public referral centers.
Cássia Cristina Pinto Mendicino, Letícia Pena Braga, Cristiane Aparecida Menezes de Pádua, Mark Drew Crosland Guimarães   +3 more
doaj   +1 more source

Acetyl‐CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

Hepatology, 2018
Pharmacologic inhibition of acetyl‐CoA carboxylase (ACC) enzymes, ACC1 and ACC2, offers an attractive therapeutic strategy for nonalcoholic fatty liver disease (NAFLD) through simultaneous inhibition of fatty acid synthesis and stimulation of fatty acid ...
L. Goedeke, J. Bates, D. Vatner, R. Perry, Ting Wang, Ricardo Ramírez, Li Li, Matthew W. Ellis, Dongyan Zhang, Kari E. Wong, C. Beysen, G. Cline, A. Ray, G. Shulman   +13 more
semanticscholar   +1 more source

Severe Hypertriglyceridemia in Pregnancy: A Case Report and Review of the Literature

AACE Clinical Case Reports, 2019
: Objective: Severe gestational hypertriglyceridemia is a rare disease, and there are no published guidelines to assist the clinician in management. However, due to the elevations in lipids that occur during pregnancy, this condition is encountered in ...
Lauren Elizabeth Kleess, MD, Natasa Janicic, MD   +1 more
doaj  

Hypertriglyceridemia and Atherosclerosis: Using Human Research to Guide Mechanistic Studies in Animal Models

Frontiers in Endocrinology, 2020
Human studies support a strong association between hypertriglyceridemia and atherosclerotic cardiovascular disease (CVD). However, whether a causal relationship exists between hypertriglyceridemia and increased CVD risk is still unclear.
Debapriya Basu, K. Bornfeldt
semanticscholar   +1 more source

Development of a Joint Prediction Model for Assessing the Severity of Hypertriglyceridemia‐Induced Acute Pancreatitis

iRADIOLOGY, EarlyView.
We found that the joint prediction model was better than the total cholesterol, low‐density lipoprotein cholesterol, modified computed tomography severity index score and liver computed tomography value, alone in assessing the performance of non‐mild hypertriglyceridemia‐induced acute pancreatitis, which can predict the severity of hypertriglyceridemia‐
Junyao Long, Junjie Kuang, Zhuoya Ma, Zhuchun Guan, Qinghong Duan   +4 more
wiley   +1 more source

PPARα Agonist Fenofibrate Reduced the Secreting Load of β-Cells in Hypertriglyceridemia Patients with Normal Glucose Tolerance

PPAR Research, 2016
Hypertriglyceridemia is an important risk factor associated with insulin resistance and β-cell dysfunction. This study investigated the effects of hypertriglyceridemia and fenofibrate treatment on insulin sensitivity and β-cell function in subjects with ...
Jia Liu, Rui Lu, Ying Wang, Yanjin Hu, Yumei Jia, Ning Yang, Jing Fu, Guang Wang   +7 more
doaj   +1 more source

Hypertriglyceridemia: new approaches in management and treatment

Current Opinion in Lipidology, 2020
Purpose of review Hypertriglyceridemia (HTG), a form of dyslipidemia characterized by elevated plasma of triglycerides (TG), is associated with an increased risk for acute pancreatitis.
A. Wolska, Zhi-Hong Yang, A. Remaley
semanticscholar   +1 more source

Lipid and lipoprotein particle profiles in patients with type 2 diabetes mellitus: A comparative study between highlanders and lowlanders

Lipids, EarlyView.
Abstract The lipid profiles of highlanders and lowlanders differ. However, studies of the lipid profiles of patients with type 2 diabetes mellitus (T2DM) living at high altitudes are limited. This study aimed to compare lipid profiles and lipoprotein particles in individuals with T2DM permanently residing in the Tibetan Plateau and those residing in ...
Chenghui Zhang, Rong Du, Suyuan Wang, Yan Ye, Xueping Sun, Yunhong Wu, Mingxia Li   +6 more
wiley   +1 more source