Results 141 to 150 of about 193,158 (291)

Double Transeptal Puncture for SAPIEN M3 Transcatheter Mitral Valve Replacement: Initial Experience, Indications, and Technique

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The SAPIEN M3 system has been recently approved for transcatheter mitral valve replacement (TMVR). The transeptal guide sheath is used to deploy the dock, which is completely released before inserting and deploying the M3 valve using the same femoral access, transeptal puncture (TSP) and guide sheath.
Clara Fernandez‐Cordon, David Hoare, Aayush Singal, Sanjeev Bhattacharyya, Suneil K. Aggarwal, Michael J. Mullen   +5 more
wiley   +1 more source

Hypertrophic cardiomyopathy in Donohue syndrome

, 2016
We report the case of a patient with Donohue syndrome who died of heart failure due to obstructive hypertrophic cardiomyopathy. A literature survey revealed that hypertrophic cardiomyopathy was present in 30% of these patients and was often fatal ...
Regenerative Medicine and Stem Cells, Cardiologie onderzoek 1, de Vroede, Monique A M J, Endocrinologie, MS Neonatologie, Cardiologie patientenzorg, Breur, Johannes M.P.J., Child Health, Termote, Jacqueline U.M.   +8 more
core  

Cytoskeleton–Membrane Uncoupling in Duchenne Muscular Dystrophy: Implications for Newborn Screening and Early Protection

Cytoskeleton, EarlyView.
ABSTRACT The cytoskeleton of striated muscle integrates force transmission, mechanotransduction, and sarcolemmal stability through coordinated networks of sarcomeres, costameres, and intermediate filaments. Together, these systems establish mechanical continuity between the contractile apparatus, the sarcolemma, and the extracellular matrix.
Houda Cohen, Nora Hosny, Brian R. Thompson, Joseph M. Metzger   +3 more
wiley   +1 more source

Assembly and Maintenance of Myofibrils in the Heart

Cytoskeleton, EarlyView.
ABSTRACT The assembly of actin and myosin to the paracrystalline arrangement of myofibrils in striated muscle, that is, heart and skeletal, has puzzled many a cell biologist. Different models, based on cultured cardiomyocytes, were proposed for the last 30 years to explain the sequence of events.
Elisabeth Ehler
wiley   +1 more source

On-pump intracardiac echocardiography during septal myectomy for hypertrophic cardiomyopathyCentral Message

JTCVS Techniques, 2020
David M. Williams, MD, Robert G. Nampi, MD, Muhamed Saric, MD, PhD, Eugene A. Grossi, MD, Mark V. Sherrid, MD, Daniel G. Swistel, MD   +5 more
doaj   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Hypertrophic myocardiopathy. Management during pregnancy and labour

, 2004
Hypertrophic cardiomyopathy is not a single disease, but a group of diseases caused by mutations in genes encoding different sarcomeric proteins. The phenotype expression depends on multiple genetic and environmental factors. In this paper, we describe a
Eguiluz, I., García-Hernández, J. A., Plasencia, W., Martín, A., Martínez-Sopena, J., Castro, N., Barber, M. A., Molo, C.   +7 more
core  

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Comparative Transcriptomic Signatures of Keloids and Hypertrophic Scars: A Genetic Association Pilot Study. [PDF]

Plast Reconstr Surg Glob Open
Barros LFL, Faustino ALF, Ribeiro-Dos-Santos Â, da Silva YCB, Quaresma JAS.   +4 more
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source