Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers
Journal of the American Heart Association, EarlyView., 2021 Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes +14 more
wiley +1 more source
Is Hypertrophic Cardiomyopathy Always a Familial and Inherited Disease?
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Jiri Bonaventura +3 more
doaj +1 more source
Role of Implantable Cardioverter Defibrillators in the Treatment of Hypertrophic Cardiomyopathy [PDF]
, 2005 Hypertrophic cardiomyopathy (HCM) is an important cardiovascular disease with sudden cardiac death as the most devastating presentation. Implantable cardioverter defibrillators (ICD) are the optimal therapy for prevention of sudden death from ventricular
Francis, Johnson +2 more
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Meta-Analyses of Septal Reduction Therapies for Obstructive Hypertrophic Cardiomyopathy [PDF]
, 2010 Robert A. Leonardi +3 more
openalex +1 more source
Prediction of cardiac death in patients with hypertrophic cardiomyopathy using RNA-sequencing of plasma small non-coding RNAS [PDF]
, 2023 Keitaro Akita +7 more
openalex +1 more source
European Journal of Heart Failure, EarlyView.In a large cohort of patients with newly diagnosed transthyretin amyloid cardiomyopathy (ATTR‐CM), echocardiographic apical sparing was associated with increased left ventricular amyloid load and atrial remodelling. Quantitative biopsy analysis revealed that Perugini scores often failed to accurately reflect myocardial amyloid burden.
Thomas Krammer +21 more
wiley +1 more source
Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]
, 2020 Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark +2 more
core
Faster cross‐bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation [PDF]
, 2014 E. Rosalie Witjas‐Paalberends +11 more
openalex +1 more source
Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)
ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang +3 more
wiley +1 more source
Journal of Intelligent Medicine, EarlyView.Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source