Results 111 to 120 of about 127,568 (322)

Enhancing explainability in clinical deep-learning models: Latent-space variable decoding is superior to gradient-weighted class activation mapping

Heart Rhythm O2
Background: Deep-learning models designed to assist with clinical decision making abound in cardiology. However, the “black box” nature of these models limits physicians’ ability to use them to cross-check clinical gestalt when evaluating model ...
Richard T. Carrick, MD, PhD, Ethan J. Rowin, MD, Alessio Gasperetti, MD, PhD, Christopher Madias, MD, Martin Maron, MD, Katherine C. Wu, MD   +5 more
doaj   +1 more source

HYPERTROPHIC CARDIOMYOPATHY: GENETIC ALTERATIONS, PATHOGENESIS AND PATHOPHYSIOLOGY

Российский кардиологический журнал, 2014
The review is dedicated to the description of genetic alterations, pathogenetic mechanisms and pathophysiology of hypertrophic cardiomyopathy, based on the analysis of current up to date information.
N. T. Vatutin, G. G. Taradin, M. S. Maron   +2 more
doaj   +1 more source

Plasma Cardiac Troponin I Concentration and Cardiac Death in Cats with Hypertrophic Cardiomyopathy [PDF]

, 2014
BACKGROUND: The use of cardiac biomarkers to assist in the diagnosis of occult and symptomatic hypertrophic cardiomyopathy (HCM) in cats has been established. There is limited data describing their prognostic utility in cats with HCM.
Abbott, Atkins, Bang, Blume, Chan, Christiaans, Coats, Connolly, Connolly, Connolly, Fernandes, Fox, Fox, Fox, Gersh, Geske, Herndon, Humm, Kittleson, Kubo, Kubo, Langhorn, Lefbom, Lyons, Maron, Maron, Maron, Moreno, Ohno-Machado, Oyama, Paige, Payne, Payne, Peacock, Perna, Perna, Rush, Schober, Schober, Schober, Singletary, Trehiou-Sechi, Wagner, Wess   +43 more
core   +1 more source

Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy: Long‐Term Follow‐Up of Deformations and Hemodynamics

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background A detailed evaluation of hemodynamics, supportive morphology, and deformation may help uncover the pathophysiology of hypertrophic obstructive cardiomyopathy (HOCM) and the changes wrought by alcohol septal ablation (ASA). Purpose To investigate the global cardiac volume, myocardial deformation, and hemodynamic characteristics ...
Kenichiro Suwa, Kazuto Ohno, Terumori Satoh, Ryota Sato, Keisuke Iguchi, Yuichiro Maekawa   +5 more
wiley   +1 more source

Obstructive Hypertrophic Cardiomyopathy and Aortic Stenosis With High Surgical Risk

JACC: Case Reports
Background: Treatment and accurate assessment of aortic valve stenosis (AS) with concomitant obstructive hypertrophic cardiomyopathy (HCM) prove challenging.
Omar M. Abdelfattah, MD, Robyn Bryde, MD, Kutaiba Nazif, MD, Matthew W. Martinez, MD   +3 more
doaj   +1 more source

Rabbit models of heart disease. [PDF]

, 2008
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core  

Hypertrophic Cardiomyopathy Gene Testing [PDF]

, 2017
Megan J. Puckelwartz, Elizabeth M. McNally   +1 more
openalex   +1 more source

Exploring Raman Spectroscopy as a Detection Tool for Cardiovascular Diseases and Diabetes Mellitus in Fingernails

Journal of Raman Spectroscopy, EarlyView.
Endogenous constituents vary between fingernails of healthy, cardiovascular and diabetic participants. Raman spectroscopy yields a biochemical fingerprint of key endogenous constituents and disease‐related biomarkers. Combined with machine learning algorithms, Raman spectroscopy can classify healthy, cardiovascular and diabetic based on their Raman ...
Megan Wilson, Dhiya Al‐Jumeily, Leung Tang, Jason Birkett, Iftikhar Khan, Ismail Abbas, Matthew Harper, Sulaf Assi   +7 more
wiley   +1 more source

Future Role of New Negative Inotropic Agents in the Era of Established Surgical Myectomy for Symptomatic Obstructive Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Barry J. Maron, Martin S. Maron, Mark V. Sherrid, Ethan J. Rowin   +3 more
doaj   +1 more source

Diffuse interstitial fibrosis assessed by cardiac magnetic resonance is associated with dispersion of ventricular repolarization in patients with hypertrophic cardiomyopathy

Journal of Arrhythmia, 2017
Background: Hypertrophic cardiomyopathy (HCM) is characterized by myocyte hypertrophy, disarray, fibrosis, and increased risk for ventricular arrhythmias.
David Hurtado-de-Mendoza, MD, Celia P. Corona-Villalobos, MD, Iraklis Pozios, MD, Jorge Gonzales, MD, Yalda Soleimanifard, MD, Sanjay Sivalokanathan, MD, Diego Montoya-Cerrillo, MD, Styliani Vakrou, MD, Ihab Kamel, MD, Wilfredo Mormontoy-Laurel, MD, Ketty Dolores-Cerna, MD, Jacsel Suarez, MD, Sergio Perez-Melo, MD, David A. Bluemke, MD, Theodore P. Abraham, MD, Stefan L. Zimmerman, MD, M. Roselle Abraham, MD   +16 more
doaj   +1 more source