Results 131 to 140 of about 55,991 (251)
Uncertainty Quantification for Cardiac Diffusion Tensor Imaging Without Additional Datasets
ABSTRACT Purpose Cardiac diffusion tensor imaging (cDTI) is subject to physiological noise, thermal noise, and signal corruption, which cause errors in diffusion measures. While a larger dataset can be decimated to investigate the general precision of measures from fitting smaller datasets, uncertainty quantification (UQ) methods for fitting entire ...
Sam Coveney +7 more
wiley +1 more source
Evaluation of a Wearable Device for Cardiorespiratory Monitoring in Healthy Anaesthetised Cats
The OSS was evaluated for heart rate and peripheral oxygen saturation monitoring in healthy anaesthetised cats. A very strong correlation was observed between OSS and a veterinary reference monitor for heart rate measurements and peripheral oxygen saturation values were clinically equivalent within predefined equivalence limits.
Şule Melek +3 more
wiley +1 more source
Systolic overload increases the synthesis of cardiac proteins, both misfolded and native, leading to cardiac hypertrophy and elevated proteostasis burden. Meanwhile, systolic overload also increases Ser14‐RPN6 phosphorylation (pS14‐RPN6), thereby increasing proteasome (Psm) proteolytic capacity and meeting the increased demand for protein degradation ...
Md. Salim Ahammed +7 more
wiley +1 more source
The cost of caution: rethinking exercise in hypertrophic cardiomyopathy. [PDF]
Saeyeldin A.
europepmc +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Artificial Intelligence for the Detection of Hypertrophic Cardiomyopathy From Standard Electrocardiogram. [PDF]
Park J +7 more
europepmc +1 more source
The 9th International RASopathies Symposium
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source
Squat in Obstructive Hypertrophic Cardiomyopathy. [PDF]
Javadi N, Galazka P, Peters M, Tajik AJ.
europepmc +1 more source
ABSTRACT Noonan syndrome (NS) is a genetically heterogeneous disorder characterized by a broad spectrum of clinical features resulting from dysregulation of the RAS/MAPK pathway. Although complex genotypes are increasingly recognized in NS, cases harboring two distinct pathogenic variants in different NS genes remain extremely rare.
Francesco Prevedello +10 more
wiley +1 more source

