Results 131 to 140 of about 55,991 (251)

Uncertainty Quantification for Cardiac Diffusion Tensor Imaging Without Additional Datasets

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 3, Page 1458-1463, September 2026.
ABSTRACT Purpose Cardiac diffusion tensor imaging (cDTI) is subject to physiological noise, thermal noise, and signal corruption, which cause errors in diffusion measures. While a larger dataset can be decimated to investigate the general precision of measures from fitting smaller datasets, uncertainty quantification (UQ) methods for fitting entire ...
Sam Coveney   +7 more
wiley   +1 more source

Evaluation of a Wearable Device for Cardiorespiratory Monitoring in Healthy Anaesthetised Cats

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
The OSS was evaluated for heart rate and peripheral oxygen saturation monitoring in healthy anaesthetised cats. A very strong correlation was observed between OSS and a veterinary reference monitor for heart rate measurements and peripheral oxygen saturation values were clinically equivalent within predefined equivalence limits.
Şule Melek   +3 more
wiley   +1 more source

PKA‐Mediated Proteasome Activation Protects Against Cardiac Remodeling and Heart Failure During Systolic Overload

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Systolic overload increases the synthesis of cardiac proteins, both misfolded and native, leading to cardiac hypertrophy and elevated proteostasis burden. Meanwhile, systolic overload also increases Ser14‐RPN6 phosphorylation (pS14‐RPN6), thereby increasing proteasome (Psm) proteolytic capacity and meeting the increased demand for protein degradation ...
Md. Salim Ahammed   +7 more
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Artificial Intelligence for the Detection of Hypertrophic Cardiomyopathy From Standard Electrocardiogram. [PDF]

open access: yesJACC Adv
Park J   +7 more
europepmc   +1 more source

The 9th International RASopathies Symposium

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1934-1941, August 2026.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel   +41 more
wiley   +1 more source

Squat in Obstructive Hypertrophic Cardiomyopathy. [PDF]

open access: yesJACC Case Rep
Javadi N, Galazka P, Peters M, Tajik AJ.
europepmc   +1 more source

Complex Genetic Architecture in RASopathies: Constitutional PTPN11 and Mosaic RIT1 Pathogenic Variants Underlying Severe Noonan Syndrome With Adult‐Onset Acute Myeloid Leukemia

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1879-1883, August 2026.
ABSTRACT Noonan syndrome (NS) is a genetically heterogeneous disorder characterized by a broad spectrum of clinical features resulting from dysregulation of the RAS/MAPK pathway. Although complex genotypes are increasingly recognized in NS, cases harboring two distinct pathogenic variants in different NS genes remain extremely rare.
Francesco Prevedello   +10 more
wiley   +1 more source

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