Results 131 to 140 of about 270,350 (354)

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

open access: yesEuropean Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard   +29 more
wiley   +1 more source

The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC

open access: yesEuropean Journal of Heart Failure, EarlyView.
Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...
Gabriele Fragasso   +20 more
wiley   +1 more source

Implantable cardioverter‐defibrillators in ischaemic versus non‐ischaemic heart failure: Insights from the VICTORIA trial

open access: yesEuropean Journal of Heart Failure, EarlyView.
Mode of death stratified by implantable cardioverter‐defibrillator (ICD) status. CI, confidence interval; CV, cardiovascular; HF, heart failure; HFrEF, heart failure with reduced ejection fraction; HR, hazard ratio; SCD, sudden cardiac death. Abstract Aims Guidelines recommend the use of implantable cardioverter‐defibrillators (ICDs) to reduce the risk
Pishoy Gouda   +11 more
wiley   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

open access: yesAdvanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li   +13 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

open access: yesJournal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes   +14 more
wiley   +1 more source

Apical Hypertrophic Cardiomyopathy: A Case Report

open access: yesCurrent Research in MRI
In this case report, a patient with apical hypertrophic cardiomyopathy (AHCM) who presented to the emergency department with chest pain is presented. The symptoms, clinical findings, diagnostic methods, differential diagnosis, and treatment options for ...
Mutlu Buyuklu   +2 more
doaj   +1 more source

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