Results 131 to 140 of about 128,678 (309)

Survival After Myectomy for Obstructive Hypertrophic Cardiomyopathy: What Causes Late Mortality? [PDF]

, 2019
Anita Nguyen, Hartzell V. Schaff, Rick A. Nishimura, Jeffrey B. Geske, Michael J. Ackerman, J. Martijn Bos, Joseph A. Dearani, Steve R. Ommen   +7 more
openalex   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Modeling of Hypertrophic Cardiomyopathy Using hiPSC-Derived Cardiomyocytes with Static Mechanical Stretching [PDF]

, 2023
Nicholas Rogozinski
openalex   +1 more source

Elucidating the cellular determinants of the end‐systolic pressure‐volume relationship of the heart via computational modelling

The Journal of Physiology, EarlyView.
Abstract figure legend Using a multiscale computational model of left ventricular electromechanics, we investigated how sarcomere dynamics influence the end‐systolic pressure‐volume (ESPV) relationship in ejecting beats compared to isovolumetric beats.
Francesco Regazzoni, Corrado Poggesi, Cecilia Ferrantini   +2 more
wiley   +1 more source

Allele-specific dysregulation of lipid and energy metabolism in early-stage hypertrophic cardiomyopathy

Journal of Molecular and Cellular Cardiology Plus
Introduction: Hypertrophic cardiomyopathy (HCM) results from pathogenic variants in sarcomeric protein genes that increase myocyte energy demand and lead to cardiac hypertrophy.
Arpana Vaniya, Anja Karlstaedt, Damla Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Styliani Vakrou, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, M. Roselle Abraham   +11 more
doaj   +1 more source

1P139 Characterization of tropomyosin mutants that cause hypertrophic cardiomyopathy (HCM) : In vitro assays with optical tweezers and heat pulse(10. Muscle,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

, 2014
Shuya Ishii, Kotaro Oyama, Madoka Suzuki, Masataka Kawai, Shin’ichi Ishiwata   +4 more
openalex   +2 more sources

Evaluation of left ventricular outflow tract obstruction with 4D phase contrast in patients with hypertrophic cardiomyopathy [PDF]

, 2014
Linda C. Chu, Celia P. Corona‐Villalobos, Mehmet Gulsun, Steven M. Shea, Michael Markl, Theodore P. Abraham, David A. Bluemke, Ihab R. Kamel, Stefan L. Zimmerman   +8 more
openalex   +1 more source

Haemodynamic‐energetic mechanism of sudden cardiac death in severe aortic stenosis: A modelling study

The Journal of Physiology, EarlyView.
Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley   +1 more source

Friedreich's ataxia associated with hypertrophic cardiomyopathy and coronary vasospasm [PDF]

, 1985
G S Sohi, Charles E. Drake, Nancy C. Flowers   +2 more
openalex   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source