Results 191 to 200 of about 56,666 (257)

Improvement of Microvascular Ischemia by Atrioventricular Sequential Pacing in Non‐Obstructive Hypertrophic Cardiomyopathy

open access: yesJournal of Arrhythmia, Volume 42, Issue 4, August 2026.
AV sequential pacing from the right ventricular apex at optimal AV delay reduced coronary sinus lactate during higher heart rates in symptomatic non‐obstructive hypertrophic cardiomyopathy, suggesting improved myocardial metabolic efficiency and reduced supply–demand mismatch.
Muthiah Subramanian   +5 more
wiley   +1 more source

Genetics in Hypertrophic Cardiomyopathy: An Evolving Clinical Landscape. [PDF]

open access: yesCard Fail Rev
Brögger MN   +3 more
europepmc   +1 more source

Coronary Microvascular Dysfunction: Epidemiology, Pathophysiology, Diagnosis, and Treatment

open access: yesMedComm, Volume 7, Issue 8, August 2026.
This visual summary illustrates the key aspects of coronary microvascular dysfunction (CMD) in angina with nonobstructive coronary artery disease (NOCAD), including epidemiology, pathophysiology (microvascular remodeling and endothelial dysfunction), the protective NRG‐1/ErbB signaling pathway, diagnostic methods, and both Western and traditional ...
Zhao Ge   +8 more
wiley   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy   +8 more
wiley   +1 more source

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong   +8 more
wiley   +1 more source

N‐Terminal Variant p.Ala2Val in X‐Linked Dyskeratosis Congenita Gene (DKC1) Disrupts Its Post‐Translational Modification and Nucleolar Localization

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.
Major symptoms of dyskeratosis congenita. Predicted nuclear localization site at N‐terminus of DKC1 protein. Comparison of nuclear localization for DKC1 showing normal localization for wild‐type versus disruption of localization for p.Ala2Val. ABSTRACT Background Dyskeratosis congenita (DKC) is typically characterized by the triad of abnormal cutaneous
Taimoor I. Sheikh, John B. Vincent
wiley   +1 more source

Deep‐Learning‐Based Image Reconstruction to Improve End‐Diastolic and Systolic Cardiac T1 Mapping

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 892-907, August 2026.
ABSTRACT Purpose To develop an image reconstruction method that enables increased spatial resolution cardiac T1 mapping in both the end‐diastolic and systolic phase, that shows high T1 agreement with the clinical standard. The resolution gain is achieved by increasing the acceleration rate of MOLLI single‐shot images to R = 4, while maintaining a ...
Daniel Amsel   +10 more
wiley   +1 more source

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