Results 61 to 70 of about 270,350 (354)

Weight loss in hypertrophic cardiomyopathy: A clinical case series

International Journal of Cardiology. Cardiovascular Risk and Prevention, 2023
Background: Obesity is prevalent among patients with hypertrophic cardiomyopathy (HCM). Obese HCM patients have greater wall thickness, LV mass, worse hemodynamic function and NYHA class. Weight loss may favorably influence the HCM phenotype.
Maria C. Reuter, Daniele Massera, Leon Axel, Larry A. Latson, Jonathan M. Goldstein, Alexandra Stepanovic, Mark V. Sherrid   +6 more
doaj  

Assessment of dynamic cardiac repolarization and contractility in patients with hypertrophic cardiomyopathy.

PLoS ONE, 2021
AimsArrhythmia mechanisms in hypertrophic cardiomyopathy remain uncertain. Preclinical models suggest hypertrophic cardiomyopathy-linked mutations perturb sarcomere length-dependent activation, alter cardiac repolarization in rate-dependent fashion and ...
Andrew E Radbill, Lucy Y Lei, Sachin Y Paranjape, Daniel J Blackwell, Robert L Abraham, Derek S Chew, Satish R Raj, Björn C Knollmann   +7 more
doaj   +1 more source

Management of hypertrophic cardiomyopathy [PDF]

BMJ, 2006
Hypertrophic cardiomyopathy is the most common familial genetic disease of the heart (1/500 to 1/1000), as well as the most common cause of sudden cardiac death in young people and athletes. Because a timely diagnosis may help to prevent sudden death, it is important for internists and general practitioners to be aware of the clinical features of the ...
P. Spirito, AUTORE, Camillo
openaire   +4 more sources

A Road Less Traveled: Successful Alcohol Septal Ablation via an Aberrant Septal Coronary Artery in Hypertrophic Obstructive Cardiomyopathy

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Alcohol septal ablation (ASA) is a minimally invasive treatment option for patients with hypertrophic obstructive cardiomyopathy (HOCM) who remain symptomatic despite medical treatment and are either poor surgical candidates or prefer a less invasive approach.
Vishnu Bharani, Vishal I. Patel, Morton J. Kern, Pranav M. Patel   +3 more
wiley   +1 more source

Advances in hypertrophic cardiomyopathy: What the cardiologist needs to know

Revista Portuguesa de Cardiologia, 2022
Hypertrophic cardiomyopathy (HCM) is known as the most common genetic heart disease, characterized by otherwise unexplained left ventricular (LV) hypertrophy.
Alexandra Toste
doaj  

Hypertrophic Cardiomyopathy: A Review

Clinical Medicine Insights: Cardiology, 2014
Hypertrophic cardiomyopathy (HCM) is a global disease with cases reported in all continents, affecting people of both genders and of various racial and ethnic origins. Widely accepted as a monogenic disease caused by a mutation in 1 of 13 or more sarcomeric genes, HCM can present catastrophically with sudden cardiac death (SCD) or ventricular ...
Brian A. Houston, Gerin R. Stevens
openaire   +5 more sources

Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny N. M. Soetedjo   +7 more
wiley   +1 more source

Evidence of Declining Mortality Trends for Hypertrophic Cardiomyopathy in the United States and the Impact of the COVID‐19 Pandemic

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Dedicated hypertrophic cardiomyopathy (HCM) center cohorts have reported reductions in HCM‐related deaths, likely due to the introduction of contemporary treatments.
Ahmed Sayed, Barry J. Maron, Ethan J. Rowin, Martin S. Maron   +3 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Management of Hypertrophic Cardiomyopathy

Annals of Global Health, 2014
Hypertrophic cardiomyopathy (HCM) is clinically defined as unexplained myocardial hypertrophy, and it is an autosomal dominant disease of the cardiac sarcomere. It is present in 1 in 500 in the general adult population, making it the most common genetic cardiovascular disease. The pathophysiology of HCM is complex, leading to significant variability in
Alan D. Enriquez, Martin E. Goldman
openaire   +4 more sources