Results 61 to 70 of about 222,830 (234)
Background Estimated plasma volume status (ePVS) estimated by the Duarte formula is associated with clinical outcomes in patients with heart failure.
Bo Shan+8 more
doaj +1 more source
Advances in hypertrophic cardiomyopathy: What the cardiologist needs to know
Hypertrophic cardiomyopathy (HCM) is known as the most common genetic heart disease, characterized by otherwise unexplained left ventricular (LV) hypertrophy.
Alexandra Toste
doaj
Hypertrophic Cardiomyopathy: A Review
Hypertrophic cardiomyopathy (HCM) is a global disease with cases reported in all continents, affecting people of both genders and of various racial and ethnic origins. Widely accepted as a monogenic disease caused by a mutation in 1 of 13 or more sarcomeric genes, HCM can present catastrophically with sudden cardiac death (SCD) or ventricular ...
Brian A. Houston, Gerin R. Stevens
openaire +5 more sources
Several lines of evidence suggest that the primary effect of hypertrophic cardiomyopathy mutations in human β-cardiac myosin is hypercontractility of the heart, which leads to subsequent hypertrophy, fibrosis, and myofilament disarray.
J. Spudich
semanticscholar +1 more source
A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice
Powering down yields a healthier heart In hypertrophic cardiomyopathy (HCM), the heart muscle enlarges and becomes progressively less efficient at pumping blood. HCM can be caused by mutations in components of the sarcomere (the heart's contractile unit),
Eric M. Green+18 more
semanticscholar +1 more source
Management of Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is clinically defined as unexplained myocardial hypertrophy, and it is an autosomal dominant disease of the cardiac sarcomere. It is present in 1 in 500 in the general adult population, making it the most common genetic cardiovascular disease. The pathophysiology of HCM is complex, leading to significant variability in
Alan D. Enriquez, Martin E. Goldman
openaire +4 more sources
Hypertrophic Cardiomyopathy: An Overview of Genetics and Management
Hypertrophic cardiomyopathy (HCM) is a genetically heterogeneous cardiac muscle disorder with a diverse natural history, characterized by unexplained left ventricular hypertrophy (LVH), with histopathological hallmarks including myocyte enlargement ...
P. Teekakirikul+3 more
semanticscholar +1 more source
Segmentation of the Myocardium on Late-Gadolinium Enhanced MRI based on 2.5 D Residual Squeeze and Excitation Deep Learning Model [PDF]
Cardiac left ventricular (LV) segmentation from short-axis MRI acquired 10 minutes after the injection of a contrast agent (LGE-MRI) is a necessary step in the processing allowing the identification and diagnosis of cardiac diseases such as myocardial infarction.
arxiv
HeartBEiT: Vision Transformer for Electrocardiogram Data Improves Diagnostic Performance at Low Sample Sizes [PDF]
The electrocardiogram (ECG) is a ubiquitous diagnostic modality. Convolutional neural networks (CNNs) applied towards ECG analysis require large sample sizes, and transfer learning approaches result in suboptimal performance when pre-training is done on natural images.
arxiv
2D : two-dimensional 99mTc-DPD : 99mTechnetium-3,3-diphosphono- 1,2-propanodi-carboxylic acid ACE : angiotensin-converting enzyme AF : atrial fibrillation AL : amyloid light chain AR : aortic regurgitation ARB : angiotensin receptor blocker ATTR ...
Perry M. Elliott+19 more
semanticscholar +1 more source