Results 1 to 10 of about 66,215 (366)

Clinical Efficacy and Safety of Cox-Maze IV Procedure for Atrial Fibrillation in Patients With Hypertrophic Obstructive Cardiomyopathy

Frontiers in Cardiovascular Medicine, 2021
Objective: Atrial fibrillation is the most prevalent persistent arrhythmia in patients with hypertrophic obstructive cardiomyopathy. Comparative analyses of the safety and effectiveness of septal myectomy with and without surgical ablation are limited ...
Yanhai Meng, Yanbo Zhang, Ping Liu, Changsheng Zhu, Tao Lu, Enci Hu, Qiulan Yang, Changrong Nie, Shuiyun Wang   +8 more
doaj   +2 more sources

Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy [PDF]

Clinics, 2013
OBJECTIVE: Obstructive sleep apnea is common among patients with hypertrophic cardiomyopathy and may contribute to poor cardiovascular outcomes. However, obstructive sleep apnea is largely unrecognized in this population.
Flávia B. Nerbass, Rodrigo P. Pedrosa, Pedro R. Genta, Murillo O. Antunes, Edmundo Arteaga-Fernández, Luciano F. Drager, Geraldo Lorenzi-Filho   +6 more
doaj   +5 more sources

Mavacamten: a first-in-class myosin inhibitor for obstructive hypertrophic cardiomyopathy [PDF]

European Heart Journal, 2023
Mavacamten is a first-in-class, targeted, cardiac-specific myosin inhibitor approved by the US Food and Drug Administration for the treatment of adults with symptomatic New York Heart Association Classes II and III obstructive hypertrophic cardiomyopathy
Abraham, Theodore P, Braunwald, Eugene, Elliott, Perry M, Olivotto, Iacopo, Saberi, Sara   +4 more
core   +5 more sources

Acquired von Willebrand Syndrome and Chronic Anaemia: A Different Diagnostic Approach [PDF]

European Journal of Case Reports in Internal Medicine, 2019
Heyde’s syndrome is a form of acquired von Willebrand syndrome that consists of bleeding from intestinal angiodysplasia in the presence of aortic stenosis (AS).
Nuno Zarcos Palma, Mariana da Cruz, Gisela Evaristo Vasconcelos, Vitor Fagundes, Lindora Pires, Mari Mesquita   +5 more
doaj   +3 more sources

Collagen Cross‐Linking Is Associated With Cardiac Remodeling in Hypertrophic Obstructive Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Collagen cross‐linking is covalent bonds among collagen fibers from catalysis of lysyl oxidase (LOX) and advanced glycation end products (AGEs).
Xuanye Bi, Yanyan Song, Yunhu Song, Jiansong Yuan, Jingang Cui, Shihua Zhao, Shubin Qiao   +6 more
doaj   +2 more sources

Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy [PDF]

New England Journal of Medicine
One of the major determinants of exercise intolerance and limiting symptoms among patients with obstructive hypertrophic cardiomyopathy (HCM) is an elevated intracardiac pressure resulting from left ventricular outflow tract obstruction. Aficamten is an oral selective cardiac myosin inhibitor that reduces left ventricular outflow tract gradients by ...
Maron, Martin S, Masri, Ahmad, Nassif, Michael E, Barriales-Villa, Roberto, Arad, Michael, Cardim, Nuno, Choudhury, Lubna, Claggett, Brian, Coats, Caroline J, Düngen, Hans-Dirk, Garcia-Pavia, Pablo, Hagège, Albert A, Januzzi, James L, Lee, Matthew M Y, Lewis, Gregory D, Ma, Chang-Sheng, Michels, Michelle, Olivotto, Iacopo, Oreziak, Artur, Owens, Anjali T, Spertus, John A, Solomon, Scott D, Tfelt-Hansen, Jacob, van Sinttruije, Marion, Veselka, Josef, Watkins, Hugh, Jacoby, Daniel L, Heitner, Stephen B, Kupfer, Stuart, Malik, Fady I, Meng, Lisa, Wohltman, Amy, Abraham, Theodore P   +32 more
openaire   +5 more sources

Outcomes in Guideline‐Based Class I Indication Versus Earlier Referral for Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background In patients with obstructive hypertrophic cardiomyopathy, surgical myectomy (SM) is indicated for severe symptoms. We sought to compare long‐term outcomes of patients with obstructive hypertrophic cardiomyopathy where SM was based on guideline‐
Alaa Alashi, Nicholas G. Smedira, Kevin Hodges, Zoran B. Popovic, Maran Thamilarasan, Per Wierup, Harry M. Lever, Milind Y. Desai   +7 more
doaj   +2 more sources

Mavacamten for hypertrophic obstructive cardiomyopathy [PDF]

The Lancet, 2021
Patrick Olivier Myers, Pietro Bajona, Eduard Quintana   +2 more
openaire   +4 more sources

Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial [PDF]

The Lancet, 2020
Abraham, T., Abraham, T. P., Afshar, K., Alvarez, P., Arad, M., Axthelm, C., Bach, R., Barriales-Villa, R., Bartunek, J., Becker, R., Bhattacharya, M., Bondue, A., Brunner-La Rocca, H. P., C. Y., Ho, Cardim, N., Charron, P., Choudhury, L., Dudek, D., Duengen, H. -D., Edelberg, J. M., Elliott, P., Fermin, D., Frey, N., Garcia Pavia, P., Garcia-Pavia, P., Gimeno Blanes, J., Gimeno-Blanes, J., Hagege, A., Halabi, M., Hegde, S. M., Hidalgo Urbano, R., Jacoby, D., Jefferies, J., Jensen, M., Jensen, M. K., Katz, A., Kramer, C., Kubanek, M., Lairez, O., Lakdawala, N., Lakdawala, N. K., Lester, S., Lester, S. J., Li, W., Marian, A., Masri, A., Maurer, M., Michels, M., Mitrovic, V., Mogensen, J., Monakier, D., Myers, J., Nagueh, S., Oko-Sarnowska, Z., Olivotto, I., Oreziak, A., Owens, A., Owens, D., Paz, O., Pereira, H., Preusch, M., Rader, F., Rincon Diaz, L. M., Saberi, S., Schulz-Menger, J., Sehnert, A. J., Seidler, T., Sherrid, M., Shirani, J., Solomon, S. D., Symanski, J., Thune, J. J., Trochu, J. -N., Turer, A., Van Craenenbroeck, E., Viskin, S., Waldman, C. B., Wang, A., Wever-Pinzon, O., Wheeler, M., Wheeler, M. T., Wojakowski, W., Wong, T., Yamani, M., Yousef, Z., Zemanek, D., Zhang, D., Zwas, D.   +87 more
core   +2 more sources

Hypertrophic Obstructive Cardiomyopathy [PDF]

Deutsches Ärzteblatt international, 2019
Hypertrophic cardiomyopathy (HCM) is caused by mutations in a number of genes. Its prevalence is 0.2% to 0.6%.This review is based on publications retrieved by a selective literature search and on the authors' clinical experi- ence.70% of patients with HCM suffer from the obstructive type of the condition, clinically characterized by highly dynamic and
Hans-Joachim Schäfers, Hubert Seggewiß, Konstantin V. Borisov, Angelika Batzner   +3 more
openaire   +4 more sources