Results 91 to 100 of about 23,884 (245)

Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy

JACC: Basic to Translational Science, 2019
Summary: Disopyramide is effective and safe in patients with obstructive hypertrophic cardiomyopathy. However, its cellular and molecular mechanisms of action are unknown.
Raffaele Coppini, MD, PhD, Cecilia Ferrantini, MD, PhD, Josè Manuel Pioner, PhD, Lorenzo Santini, MS, Zhinuo J. Wang, PhD, Chiara Palandri, MS, Marina Scardigli, PhD, Giulia Vitale, MS, Leonardo Sacconi, PhD, Pierluigi Stefàno, MD, Laura Flink, MD, Katherine Riedy, MD, Francesco Saverio Pavone, PhD, Elisabetta Cerbai, PhD, Corrado Poggesi, MD, Alessandro Mugelli, MD, Alfonso Bueno-Orovio, PhD, Iacopo Olivotto, MD, Mark V. Sherrid, MD   +18 more
doaj   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

MYOCARDIAL INFARCTION WITHOUT OBSTRUCTIVE CORONARY ARTERY DISEASE IN A PATIENT WITH HYPERTROPHIC CARDIOMYOPATHY

Байкальский медицинский журнал
Background. Myocardial infarction with non-obstructive coronary arteries is defined by the presence of clinical symptoms and signs of myocardial infarction despite angiographic findings of normal or near-normal coronary arteries.
Elena Sergeevna Eniseeva, Tatiana Petrovna Vlasyuk   +1 more
doaj   +1 more source

Alcohol septal ablation: patient selection and rationality of its application

Патология кровообращения и кардиохирургия, 2017
The article looks at some aspects of selecting patients with obstructive hypertrophic cardiomyopathy for alcohol septal ablation (ASA) procedure. Based on the world’s experience and in the context of evidence-based medicine, the current positions of ASA ...
М. Г. Каштанов, С. Д. Чернышев, Л. В. Кардапольцев, С. В. Бердников, Э. М. Идов   +4 more
doaj   +1 more source

Echocardiographic findings late after myectomy in hypertrophic obstructive cardiomyopathy [PDF]

, 2017
Postoperative echocardiograms of 50 patients undergoing myectomy for hypertrophic obstructive cardiomyopathy between 1965 and 1982 have been evaluated. In 21 patients a comparison with preoperative echocardiograms showed that postoperatively there was a ...
JENNI, R., KRAYENBUEHL, H.P., ROTHLIN, M., TURINA, J., TURINA, M.   +4 more
core  

Prostate Cancer, Genetic Susceptibility, and Risk of Chronic Non‐Urological Complications

The Prostate, EarlyView.
ABSTRACT Background Chronic nonurological complications are common among prostate cancer (PCa) survivors; however, their spectrum, magnitude, and genetic contribution remain poorly characterized. Methods We evaluated 15 commonly reported nonurological complications and tested their associations with exposure to PCa and disease‐specific polygenic risk ...
Brian T. Helfand, Zhuqing Shi, Ashley J. Mulford, Huy Tran, Jun Wei, Annabelle Ashworth, S. Lilly Zheng, Alan R. Sanders, Nathan Graham, Joshua Cabral, Jim Lu, Jennifer L. Beebe‐Dimmer, Kathleen A. Cooney, David Duggan, Jianfeng Xu   +14 more
wiley   +1 more source

Anesthetic management of a patient with hypertrophic obstructive cardiomyopathy undergoing modified radical mastectomy. [PDF]

, 2010
Hypertrophic obstructive cardiomyopathy (HOCM) is a rare genetic disorder characterized by left ventricular outflow tract (LVOT) obstruction. Clinical presentation ranges from absence of symptoms to sudden death.
Ahmed, Aliya, Hoda, Muhammad Q, Ullah, Hameed, Zaidi, Raza A   +3 more
core  

Speckle tracking: distinction of physiologic from pathologic LVH? [PDF]

, 2010
Ventricular Dysfunction & Heart ...
E. E. van der Wall, V. Delgado, E. R. Holman, J. J. Bax   +3 more
core   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, EarlyView.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source

A rare case report of hypertrophic cardiomyopathy induced by catecholamine-producing tumor [PDF]

, 2018
RATIONALE: Catecholamine-producing tumors are rare, occurring in less than 0.2% of patients with hypertension, but can have relevant cardiovascular morbidity and mortality. PATIENT CONCERNS: A 37-year-old woman presented with a history of dyspnea, chest
Bisogni, Valeria, Bonvicini, Maria, Ciardi, Antonio, Concistré, Antonio, De Toma, Giorgio, Frustaci, Andrea, Iannucci, Gino, Letizia, Claudio, Mezzadri, Martina, Oliviero, Gaia, Olmati, Federica, Petramala, Luigi, Saracino, Vincenza   +12 more
core   +1 more source