Results 101 to 110 of about 286,742 (224)

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

A locus on chromosome 5 is associated with dilated cardiomyopathy in Doberman Pinschers [PDF]

, 2011
Dilated cardiomyopathy (DCM) is a heterogeneous group of heart diseases with a strong genetic background. Currently, many human DCM cases exist where no causative mutation can be identified.
Matthew T. Webster, Gerhard Wess, Stephenson Hannah, Hannah Stephenson, Wess, G., Stephenson, Hannah, Cord Drögemüller, Webster, Matthew T., Mausberg, T.B., Webster, Matthew T.,, Webster, M.T., Dukes-McEwan, Joanna, Keller Lisa, Stephenson, H., Drögemüller, Michaela, Matthew T Webster, Leeb Tosso, Simak Julia, Droegemueller, Cord, Keller, L., Lisa Keller, Simak, J., Michaela Drögemüller, Simak, Julia, Dukes-McEwan, J., Joanna Dukes-McEwan, Tosso Leeb, Wess Gerhard, Mausberg, Theresa-Bernadette, Theresa-Bernadette Mausberg, Mausberg Theresa-Bernadette, Webster Matthew T., Droegemueller, Michaela, Wess, Gerhard, Drögemüller Cord, Drögemüller, Cord, Leeb, Tosso, Dukes-McEwan Joanna, Julia Simak, Drögemüller Michaela, Keller, Lisa   +40 more
core   +2 more sources

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Biventricular Hypertrophic Cardiomyopathy in a Child with LEOPARD Syndrome: a Case Report

Journal of Interdisciplinary Medicine, 2017
Background: LEOPARD syndrome is a complex dysmorphogenetic disorder of inconstant penetrance and various morphologic expressions. The syndrome is an autosomal dominant disease that features multiple lentigines, electrocardiographic changes, eye ...
Blesneac Cristina, Șuteu Carmen-Corina, Bănescu Claudia, Benedek Theodora, Benedek Imre, Togănel Rodica   +5 more
doaj   +1 more source

Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel, G. W. Wilkerson, L. Yan, C. L. Hodo, S. M. Kezar   +4 more
wiley   +1 more source

Midventricular Obstructive Hypertrophic Cardiomyopathy with Apical Aneurysm: Left Ventricular Hemodynamic and Angiographic Findings: Midventricular Obstructive Hypertrophic Cardiomyopathy

, 2022
A case of a 50-year-old patient with a midventricular obstructive hypertrophic cardiomyopathy is presented and the left ventricular hemodynamic and angiographic findings are depicted and discussed.
Manolis, Antonis A., Manolis, Antonis S
core   +1 more source

Hypertrophic Obstructive Cardiomyopathy

, 2020
Hypertrophic cardiomyopathy is a genetic cardiac disorder caused by a missense mutation in 1 of at least 10 genes that encode the proteins of the cardiac sarcomere.
Jonathan Downloaded From Www.Nejm.Org By, Poveda F Md On   +1 more
core   +1 more source

Is subcutaneous fat tissue embolization effective and safe as a septal reduction technique in a patient with hypertrophic obstructive cardiomyopathy?

Türk Kardiyoloji Derneği Arşivi, 2018
Hypertrophic obstructive cardiomyopathy is an inheritable cardiac disease that typically manifests with an increased left ventricular outflow tract gradient.
Elnur Alizade, Sabahattin Gündüz, Ahmet Güner, Khagani Isgandarov, Selçuk Pala   +4 more
doaj   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

Analysis of desmoplakin in arrythmogenic right ventricular cardiomyopathy [PDF]

, 2010
Includes bibliographical references (leaves 71-79).It has been shown that all forms of cardiomyopathy, including the dilated, hypertrophic, restrictive, and right ventricular arrhythmogenic forms, are found in African populations.
Fish, Maryam
core   +1 more source