Results 101 to 110 of about 27,986 (275)

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Eighteen‐Month Real‐World Experience Using Mavacamten for Treatment of Obstructive Hypertrophic Cardiomyopathy in a Racially Diverse Population

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Patients with obstructive hypertrophic cardiomyopathy have increased symptomatic burden. Mavacamten was recently approved for treatment of obstructive hypertrophic cardiomyopathy based on 2 randomized controlled trials.
Diego Ramonfaur, Alessio Gasperetti, Victoria E. Blake, Bryana Rivers, Ali A. Kassamali, Edward K. Kasper, Lili A. Barouch, Katherine C. Wu, Jose A. Madrazo, Richard T. Carrick   +9 more
doaj   +1 more source

Surgical treatment versus medical treatment in hypertrophic obstructive cardiomyopathy [PDF]

, 2017
Sixty-three patients operated upon for HOCM and 49 patients selected for non-surgical treatment have been followed-up for 15 years. Pre-operatively, surgical patients had a higher left ventricular outflow tract gradient at rest and, on the average, more ...
Gobet, D., Haberer, T., Krayenbuehl, H. P., Rothlin, M. E., Senning, Å., Turina, M.   +5 more
core  

Cats with thermal burn injuries from California wildfires show echocardiographic evidence of myocardial thickening and intracardiac thrombi. [PDF]

, 2020
Recent increases in the prevalence and severity of wildfires in some regions have resulted in an increased frequency of veterinary burn patients. Few studies exist regarding diagnostics and management of burn wounds in veterinary patients and current ...
Epstein, Steven E, Gunther-Harrington, Catherine T, Li, Ronald HL, Sharpe, Ashley N, Stern, Joshua A   +4 more
core  

HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY [PDF]

Heart, 1964
J, COHEN, H, EFFAT, J F, GOODWIN, C M, OAKLEY, R E, STEINER   +4 more
openaire   +2 more sources

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Echocardiographic Changes Following Surgical Myectomy in Severely Symptomatic Obstructive Hypertrophic Cardiomyopathy: Insights From the SPIRIT‐HCM Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background In obstructive hypertrophic cardiomyopathy, myectomy improves symptoms, quality of life, and left ventricular (LV) outflow tract gradients. We prospectively evaluated the temporal changes in various echo parameters after myectomy.
Milind Y. Desai, Natalie Szpakowski, Albree Tower‐Rader, Barb Bittel, Agostina Fava, Susan Ospina, Bo Xu, Maran Thamilarasan, Amgad Mentias, Nicholas G. Smedira, Zoran B. Popovic   +10 more
doaj   +1 more source

Is subcutaneous fat tissue embolization effective and safe as a septal reduction technique in a patient with hypertrophic obstructive cardiomyopathy?

Türk Kardiyoloji Derneği Arşivi, 2018
Hypertrophic obstructive cardiomyopathy is an inheritable cardiac disease that typically manifests with an increased left ventricular outflow tract gradient.
Elnur Alizade, Sabahattin Gündüz, Ahmet Güner, Khagani Isgandarov, Selçuk Pala   +4 more
doaj   +1 more source

Hypertrophic Cardiomyopathy - Past, Present and Future [PDF]

, 2017
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy with a prevalence of 1 in 500 in the general population. Since the first pathological case series at post mortem in 1957, we have come a long way in its understanding, diagnosis ...
Brock, Hallopeau, Liouville, Maron, Pridie, Vulpian   +5 more
core   +2 more sources

Surgical septal myectomy outcome for obstructive hypertrophic cardiomyopathy after alcohol septal ablation [PDF]

, 2021
Qiulan Yang, Changsheng Zhu, Hao Cui, Bing Tang, Shuiyun Wang, Qinjun Yu, Shihua Zhao, Yunhu Song, Shuiyun Wang   +8 more
openalex   +1 more source