Results 41 to 50 of about 66,215 (366)

Clinical efficacy of CARTOSound-guided radiofrequency ablation for hypertrophic obstructive cardiomyopathy

open access: yesDi-san junyi daxue xuebao, 2021
Objective To investigate the clinical efficacy of CARTOSound-guided radiofrequency ablation on hypertrophic obstructive cardiomyopathy. Methods The consecutive patients with hypertrophic obstructive cardiomyopathy accompanied with systolic anterior ...
JIANG Zhouqin   +6 more
doaj   +1 more source

Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]

open access: yes, 2014
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core   +2 more sources

Hypertrophic Cardiomyopathy [PDF]

open access: yesCirculation, 2006
Hypertrophic cardiomyopathy is a fascinating disease entity in which hypertrophy of the myocardium occurs, primarily as a result of mutations of genes encoding the cardiac sarcomere.1–3 Our knowledge of patients with this unique disease of the heart muscle has advanced significantly.
Steve R. Ommen, Rick A. Nishimura
openaire   +3 more sources

The right ventricle under pressure: Anatomy and imaging in sickness and health

open access: yesJournal of Anatomy, Volume 242, Issue 1, Page 17-28, January 2023., 2023
The RV is essential to the homeostasis of normal physiology and disturbances in RV structure and function has a substantial effect on patient outcomes. This review sets out to describe the developmental and anatomical complexities of the right ventricle while exploring the modern techniques employed to image and understand its function from a clinical ...
Harrison Stubbs   +4 more
wiley   +1 more source

Cardiotoxicity with vascular endothelial growth factor inhibitor therapy [PDF]

open access: yes, 2018
Angiogenesis inhibitors targeting the vascular endothelial growth factor (VEGF) signaling pathway (VSP) have been important additions in the therapy of various cancers, especially renal cell carcinoma and colorectal cancer.
Herrmann, Joerg, Touyz, Rhian M.
core   +2 more sources

Pharmacokinetics of a single dose of Aficamten (CK‐274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 52-61, January 2023., 2023
Abstract Hypertrophic cardiomyopathy (HCM) is the most prevalent cardiac disease in cats and lacks efficacious preclinical pharmacologic intervention, prompting investigation of novel therapies. Genetic mutations encoding sarcomeric proteins are implicated in the development of HCM and small molecule myosin inhibitors are an emerging class of ...
Ashley N. Sharpe   +9 more
wiley   +1 more source

MYOCARDIAL REMODELLING TYPES IN HYPERTROPHIC NON-OBSTRUCTIVE CARDIOMYOPATHY

open access: yesРоссийский кардиологический журнал, 2015
Aim. To evaluate the prevalence of the left ventricle remodeling types in hypertrophic non-obstructive cardiomyopathy, and their relation to clinical and instrumental data. Material and methods.
D. V. Bogdanov
doaj   +1 more source

Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus). [PDF]

open access: yes, 2017
Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll ...
Chan, J   +5 more
core   +2 more sources

Surgical Treatment for Severe Cervical Hyperlordosis and Thoracolumar Kyphoscoliosis with Emery–Dreifuss Muscular Dystrophy: A Case Report and Literature Review

open access: yesOrthopaedic Surgery, Volume 14, Issue 12, Page 3448-3454, December 2022., 2022
In patients with Emery–Dreifuss muscular dystrophy (EDMD), cervical deformity secondary to contractures of posterior cervical muscle in such patients should be corrected in the first stage considering its role as a “driver” of the global spine deformity.
Ziyang Tang   +4 more
wiley   +1 more source

Modern Perspectives on Hypertrophic Cardiomyopathy—No One Size Fits All [PDF]

open access: yesTexas Heart Institute Journal
Despite substantial advances in the management of hypertrophic cardiomyopathy, advanced heart failure remains a major cause of morbidity in this patient population.
Brett Doliner, MD   +3 more
doaj   +1 more source

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