Results 41 to 50 of about 66,215 (366)
Objective To investigate the clinical efficacy of CARTOSound-guided radiofrequency ablation on hypertrophic obstructive cardiomyopathy. Methods The consecutive patients with hypertrophic obstructive cardiomyopathy accompanied with systolic anterior ...
JIANG Zhouqin+6 more
doaj +1 more source
Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core +2 more sources
Hypertrophic Cardiomyopathy [PDF]
Hypertrophic cardiomyopathy is a fascinating disease entity in which hypertrophy of the myocardium occurs, primarily as a result of mutations of genes encoding the cardiac sarcomere.1–3 Our knowledge of patients with this unique disease of the heart muscle has advanced significantly.
Steve R. Ommen, Rick A. Nishimura
openaire +3 more sources
The right ventricle under pressure: Anatomy and imaging in sickness and health
The RV is essential to the homeostasis of normal physiology and disturbances in RV structure and function has a substantial effect on patient outcomes. This review sets out to describe the developmental and anatomical complexities of the right ventricle while exploring the modern techniques employed to image and understand its function from a clinical ...
Harrison Stubbs+4 more
wiley +1 more source
Cardiotoxicity with vascular endothelial growth factor inhibitor therapy [PDF]
Angiogenesis inhibitors targeting the vascular endothelial growth factor (VEGF) signaling pathway (VSP) have been important additions in the therapy of various cancers, especially renal cell carcinoma and colorectal cancer.
Herrmann, Joerg, Touyz, Rhian M.
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Abstract Hypertrophic cardiomyopathy (HCM) is the most prevalent cardiac disease in cats and lacks efficacious preclinical pharmacologic intervention, prompting investigation of novel therapies. Genetic mutations encoding sarcomeric proteins are implicated in the development of HCM and small molecule myosin inhibitors are an emerging class of ...
Ashley N. Sharpe+9 more
wiley +1 more source
MYOCARDIAL REMODELLING TYPES IN HYPERTROPHIC NON-OBSTRUCTIVE CARDIOMYOPATHY
Aim. To evaluate the prevalence of the left ventricle remodeling types in hypertrophic non-obstructive cardiomyopathy, and their relation to clinical and instrumental data. Material and methods.
D. V. Bogdanov
doaj +1 more source
Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus). [PDF]
Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll ...
Chan, J+5 more
core +2 more sources
In patients with Emery–Dreifuss muscular dystrophy (EDMD), cervical deformity secondary to contractures of posterior cervical muscle in such patients should be corrected in the first stage considering its role as a “driver” of the global spine deformity.
Ziyang Tang+4 more
wiley +1 more source
Modern Perspectives on Hypertrophic Cardiomyopathy—No One Size Fits All [PDF]
Despite substantial advances in the management of hypertrophic cardiomyopathy, advanced heart failure remains a major cause of morbidity in this patient population.
Brett Doliner, MD+3 more
doaj +1 more source