Results 71 to 80 of about 21,074 (284)

H2FPEF and HFA‐PEFF scores for heart failure risk stratification in hypertrophic cardiomyopathy patients

ESC Heart Failure, EarlyView.
Abstract Aims H2FPEF and HFA‐PEFF scores have demonstrated prognostic value in heart failure (HF) with preserved ejection fraction. This study aimed to explore the value of the H2FPEF and HFA‐PEFF scores for HF risk stratification in patients with hypertrophic cardiomyopathy (HCM).
Yi‐Peng Gao, Hong‐Yun Liu, Xiao‐Jun Bi, Jie Sun, Ying Zhu, Wei Zhou, Ya‐Ting Fan, Xue‐Qing Cheng, Pei‐Na Huang, Ya‐Ni Liu, You‐Bin Deng   +10 more
wiley   +1 more source

Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

ESC Heart Failure, EarlyView.
Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem, Teresa C. Leone, Christopher Petucci, Clarissa Shoffler, Ravindra C. Kodihalli, Tiffany Hidalgo, Cheryl Tow‐Keogh, Jessica Mancuso, Iphigenia Tzameli, Donald Bennett, John D. Groarke, Rachel J. Roth Flach, Daniel J. Rader, Daniel P. Kelly   +13 more
wiley   +1 more source

Clinical characteristics and long‐term outcomes in patients with apical hypertrophic cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims As a special type of hypertrophic cardiomyopathy (HCM), apical HCM (ApHCM) has different clinical characteristics while its nature history and prognosis are not well recognized. We aimed to describe the characteristics and outcomes of ApHCM and identify predictors of adverse outcomes.
Meng Guo, Chuanfen Liu, Jingjing Ye, Jian Liu   +3 more
wiley   +1 more source

Hypertrophic obstructive cardiomyopathy [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 1997
Morton E. Tavel, Nora Goldschlager, Lameh Fananapazir   +2 more
openaire   +5 more sources

MYOCARDIAL INFARCTION WITHOUT OBSTRUCTIVE CORONARY ARTERY DISEASE IN A PATIENT WITH HYPERTROPHIC CARDIOMYOPATHY

Байкальский медицинский журнал
Background. Myocardial infarction with non-obstructive coronary arteries is defined by the presence of clinical symptoms and signs of myocardial infarction despite angiographic findings of normal or near-normal coronary arteries.
Elena Sergeevna Eniseeva, Tatiana Petrovna Vlasyuk   +1 more
doaj   +1 more source

The risk of death according to left ventricular ejection fraction and right ventricular dilatation in 17 321 adults with heart failure from 40 high‐, middle‐ and low‐income countries – A Global Congestive Heart Failure (G‐CHF) study

European Journal of Heart Failure, EarlyView.
Abstract Aims The aim of this study was to describe the prognostic importance of left ventricular ejection fraction (LVEF) versus right ventricular (RV) dilatation and dysfunction in patients with heart failure (HF) from countries of different income levels. Methods and results We enrolled 17 321 participants with HF from 40 countries.
Darryl P. Leong, Philip G. Joseph, Hisham Dokainish, Stefan Störk, John V.V. McMurray, Lisa M. Mielniczuk, Sanjib Kumar Sharma, Andrés Orlandini, Kamilu M. Karaye, Antoni Bayes‐Genis, Tara McCready, Alex Grinvalds, Kumar Balasubramanian, Kelley R. Branch, Kristian Kragholm, Salim Yusuf, on behalf of the G‐CHF Investigators   +16 more
wiley   +1 more source

Continuous risk monitoring and management of heart failure: Rationale and design of the ALLEVIATE‐HF trial

European Journal of Heart Failure, EarlyView.
Design of the ALLEVIATE‐HF study with schematic of win ratio analysis stratified by left ventricular ejection fraction (LVEF) ≥50% versus LVEF <50%. ∆, change; 6MWT, 6‐min walk test; BNP, B‐type natriuretic peptide; CIED, cardiac implantable electronic device; CV, cardiovascular; EQ‐5D, EuroQol 5‐Dimension Questionnaire; HF, heart failure; ICM ...
Javed Butler, Rami Kahwash, Muhammad Shahzeb Khan, Bart Gerritse, Aimee Laechelt, Jennifer Wehking, Shantanu Sarkar, Brian van Dorn, Verla Laager, Nirav Patel, Michael R. Zile, on behalf of the ALLEVIATE‐HF Investigators   +11 more
wiley   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

Advanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li, Nicolas De Jay, Shan‐Shan Zhang, Xin Fang, Supriya Sharma, Katrina A. Catalano, Venkatesh Sridharan, Zhaoqing Wang, Lei Zhao, Joseph D. Szustakowski, Ching‐Pin Chang, Joseph C. Maranville, Emily R. Holzinger, Erika M. Kvikstad   +13 more
wiley   +1 more source

Drug–Drug Interaction Potential of Mavacamten with Midazolam: Combined Results from Clinical and Model‐Based Studies

The Journal of Clinical Pharmacology, EarlyView.
Abstract Mavacamten is a potential inducer of cytochrome P450 (CYP) 3A4 and could reduce the effectiveness of concomitant drugs that are metabolized by CYP3A4, such as midazolam. This study aimed to determine if repeat doses of mavacamten achieving clinically relevant exposures affected midazolam exposure.
Samira Merali, Caroline Sychterz, Vidya Perera, Lu Gaohua, Victoria Florea, Bindu Murthy   +5 more
wiley   +1 more source

Genetic testing and counseling for hypertrophic cardiomyopathy: An evidence‐based practice resource of the National Society of Genetic Counselors

Journal of Genetic Counseling, EarlyView.
Abstract Hypertrophic cardiomyopathy (HCM) is a common hereditary condition affecting approximately 1 in 500 adults. It is characterized by marked clinical heterogeneity with individuals experiencing minimal to no symptoms, while others may have more severe outcomes including heart failure and sudden cardiac death.
Erin M. Miller, Emily Brown, Susan Christian, Melissa A. Kelly, Linda M. Knight, Sara Saberi, Christina Rigelsky, Jodie Ingles   +7 more
wiley   +1 more source