Results 181 to 190 of about 196,988 (294)

Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice

Pediatric Discovery, EarlyView.
This study examined the relationship between aortic arch stiffness and lung function in aging mice. Multiple linear regression modeling showed moderate to strong correlations between the rise in aortic arch stiffness and changes in lung function as the mice progressively aged.
Ayman Isbatan, Samuel M. Lee, Ali Imran Sarwar, Yuxing Yuan, Sunny Chen, Maricela Castellon, Dan A. Marian, Richard D. Minshall, Jie Tian, Irena Levitan, Jiwang Chen   +10 more
wiley   +1 more source

Reversible Systolic Anterior Motion in the Absence of Left Ventricular Hypertrophy Following Acute Myocardial Infarction: A Report of a Rare Case. [PDF]

Cureus
Chaddad R, Hakim M, Carreira V, Khater J.   +3 more
europepmc   +1 more source

Machine learning‐based predictive models versus traditional risk scores in hemodialysis patients with comorbid urolithiasis

Precision Medical Sciences, EarlyView.
Machine learning‐based predictive models outperform traditional risk scores in hemodialysis patients with comorbid urolithiasis by capturing nonlinear, dialysis‐specific interactions. These approaches enable more accurate prediction of stone recurrence, sepsis, hospitalization, and mortality, supporting personalized risk stratification and precision ...
Dipal Chaulagain, Muhammad Riaz, Mirza Muhammad Hadeed Khawar, Jawad Hameed, Malik Sohail Riaz   +4 more
wiley   +1 more source

Spontaneous myocardial injury in hypertrophic cardiomyopathy: Coexistence of microvascular dysfunction and microvascular obstruction. [PDF]

Radiol Case Rep
Panyawongkhanti M, Theerasuwipakorn N, Khongphatthanayothin A, Chattranukulchai P.   +3 more
europepmc   +1 more source

[LEFT VENTRICULAR HYPERTROPHY].

Kardiologia polska, 1996
J, MIZERA, R, FENIGSEN
openaire   +1 more source

Amentoflavone, a Preferentially TGF‐β Receptor 1 Inhibitor, Alleviates Cardiac Remodeling and Dysfunction Through Modulating the TGF‐β/Smad and MAPK Signaling Pathways

Phytotherapy Research, EarlyView.
Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu, Chengcheng Zhao, Xiaoping Li, Xinyi Guo, Wenjie Tan, Lu Zhou, Ye Zhang, Jianli Zhang, Shuo Zheng, Chunyu Zeng, Gengze Wu   +10 more
wiley   +1 more source

Apical Sparing of Longitudinal Strain and Myocardial Fibrosis in Hypertensive Patients and Spontaneously Hypertensive Rats: Based on Speckle Tracking and Histological Analysis. [PDF]

Clin Cardiol
Huang C, Wu Y, Lin M, Chen Y, Lin S, Fu L, Huang H.   +6 more
europepmc   +1 more source

Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A

Phytotherapy Research, EarlyView.
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen, Xinghong Zhou, Yanting You, Jieyu Chen, Baizhao Peng, Yijian Deng, Shuai Ji, Ying Yang, Xiaohu Chen, Huaxi Liu, Shuxuan Yang, Hiu Yee Kwan, Wen Jin, Lei Zhang, Yuegang Wang, Xiaoshan Zhao, Yanyan Liu   +16 more
wiley   +1 more source

An unusual trilogy: a case of comorbid aHUS, Fabry disease, and hypertrophic cardiomyopathy. [PDF]

Front Med (Lausanne)
Li Q, Yu L, Wang J, Yang Z, Duan Y, Zhen J, Sun S.   +6 more
europepmc   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, EarlyView.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source