Results 131 to 140 of about 528,761 (298)

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

Cell, 1998
J. Molkentin, Jian-rong Lu, C. Antos, B. Markham, J. Richardson, J. Robbins, S. R. Grant, E. Olson   +7 more
semanticscholar   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Therapeutic Modulation of Mitophagy by Cafestol in Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis [PDF]

Wen‐Rui Hao, Chun‐Chao Chen, Guojin Huang, Jia-Hong Lin, Huan‐Yuan Chen, Ju-Chi Liu, Tzu‐Hurng Cheng, Jin-Jer Chen   +7 more
openalex   +1 more source

The Relationship Between High‐Sensitivity C‐Reactive Protein Levels and Left Ventricular Hypertrophy in Patients With Newly Diagnosed Hypertension [PDF]

, 2015
Ergün Seyfeli, Bahadır Şarlı, Hayrettin Sağlam, Can Y. Karatas, Eyüp Özkan, Mehmet Uğurlu   +5 more
openalex   +1 more source

Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate [PDF]

, 2023
Mahdia Taieb, Dima Ghannoum, Lydia Barré, Mohamed Ouzzine   +3 more
openalex   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

An Unexpected Cause of Asymmetric Left Ventricular Hypertrophy [PDF]

Matteo Beltrami, M.G. Papi, Iacopo Olivotto, Raffaella Santi, Gabriella Nesi, Maurizio Pieroni, Pierluigi Stefàno   +6 more
openalex   +1 more source

Viral gametocytic hypertrophy of Crassostrea gigas in France: from occasional records to disease emergence? [PDF]

, 2006
Carlos Alexandre Borges Garcia, M. Robert, Isabelle Arzul, Bruno Chollet, JP Joly, L. Miossec, Thierry Comtet, Franck Berthe   +7 more
openalex   +1 more source

FGF23 induces left ventricular hypertrophy.

Journal of Clinical Investigation, 2011
C. Faul, A. Amaral, Behzad N. Oskouei, M. Hu, A. Sloan, T. Isakova, O. Gutiérrez, Robier Aguillon-Prada, J. Lincoln, J. Hare, P. Mundel, Azorides R. Morales, J. Scialla, M. Fischer, E. Soliman, J. Chen, A. Go, S. Rosas, L. Nessel, R. Townsend, H. Feldman, M. G. St. John Sutton, A. Ojo, C. Gadegbeku, G. D. Di Marco, S. Reuter, Dominik Kentrup, K. Tiemann, M. Brand, Joseph A. Hill, O. Moe, M. Kuro-o, J. Kusek, M. Keane, M. Wolf   +34 more
semanticscholar   +1 more source

Anatomical and Functional Assessment of Upper Airway Performance Using Innovative NasoOroSpirometer and Cone Beam Computed Tomographic Diagnostic Devices in Children with Adenoid Hypertrophy -- Observational Study [PDF]

Edyta Zomkowska, Sylwia Grzybowska-Detka, Magdalena Zakrzewska, Jerzy Romaszko, Robert Barański, A. Zając, Hanna Zajączkiewicz, Szymon Nitkiewicz, Andrzej Kukwa   +8 more
openalex   +1 more source