Results 141 to 150 of about 549,472 (306)
Impact of Recanalization on Liver Hypertrophy after Portal Vein Embolization and the Role of Re‐Embolization
Annals of Gastroenterological Surgery, EarlyView.This retrospective study of 249 patients undergoing hepatectomy after right portal vein embolization (PVE) demonstrated that major recanalization–defined as recanalization more than one segment within the embolized liver–was associated with impaired regeneration of the future liver remnant (FLR).Masao Uemura, Shimpei Otsuka, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Rui Sato, Takeshi Aramaki, Akifumi Notsu, Katsuhiko Uesaka, Teiichi Sugiura +9 morewiley +1 more sourceProfiling Co‐Occurrent Morphological Phenotypes and Their Degree of Expression Severity in Vacuolated Cells by Holo‐Tomographic Flow Cytometry and Fractal Analysis
Advanced Intelligent Systems, EarlyView.HTFC gets 3D refractive index tomograms of flowing cells. Label‐free monocytes are engineered to express patterns of cytoplasmic vacuoles. From the tomogram, an efficient dimensionality reduction is operated. Interpretable features are extracted to classify the expression severity of phenotypes coexisting in each cell, visually represented by a seven ...Marika Valentino, Giusy Giugliano, Daniele Pirone, Fabrizio Licitra, Fulvia Vitale, Pasquale Memmolo, Lisa Miccio, Massimo D’Agostino, Pietro Ferraro, Vittorio Bianco +9 morewiley +1 more sourceSafety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience
American Journal of Hematology, EarlyView.ABSTRACT
Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a Bruno Fattizzo, Elisa Sambruna, Yoshitaka Miyakawa, Marc Michel, Carlo Visco, Michael Fillitz, George Kannourakis, Maria Bruna Greve, Moritz Kleemiss, Johan Cid, Andrea Patriarca, Laura Pavan, Arbana Dizdari, Nilla Maschio, Antonella Sau, Cinzia Bitetti, Riccardo Mario Colombo, Luigi Curreli, Dorela Lame, Uros Markovic, Fabrizio Pappagallo, Giacinto Luca Pedone, Davide Rapezzi, Vincenzo Sammartano, Nicola Tumedei, Antonio Giovanni Solimando, Jalink Marit, Luana Fianchi, Jahanzaib Khwaja, Antonio De Vivo, Francesco Lanza, Fabrizio Vianello, Esther N. Oliva, Catherine Broome, Francesco Passamonti, Ulrich Jaeger, Bernd Jilma, Guillaume Moulis, Wilma Barcellini +38 morewiley +1 more sourceThe Novel ACTC1 p.Gly50Ser Variant Is Associated With Arrhythmia and Secondary Features of HCM Without Hypertrophy
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT
The key diagnostic criterion for hypertrophic cardiomyopathy is the presence of otherwise unexplained hypertrophy. Current definitions of HCM rely on specific thresholds to establish a diagnosis, while guideline directed risk stratification algorithms take its magnitude into consideration.Thomas D. Gossios, Dimitrios Ntelios, Thomas Zegkos, Despoina Parcharidou, Pavlos Rouskas, Sotirios Katranas, Ioannis Papoulidis, Vlasis Ninios, Antonios Ziakas, Georgios K. Efthimiadis +9 morewiley +1 more sourceDifferentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT
The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot +4 morewiley +1 more sourceResolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT
Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond +11 morewiley +1 more sourceHypertrophy [PDF]
, 2013 Sheina Orbell, Havah Schneider, Sabrina Esbitt, Jeffrey S. Gonzalez, Jeffrey S. Gonzalez, Erica Shreck, Abigail Batchelder, Yori Gidron, Sarah D. Pressman, Emily D. Hooker, Deborah J. Wiebe, Deborah Rinehart, Laura L. Hayman, Luigi Meneghini, Hiroe Kikuchi, Hiroe Kikuchi, Tamer F. Desouky, Lisa M. McAndrew, Pablo A. Mora, Bonnie Bruce, Tana M. Luger, Peter Allebeck, Peter Allebeck, Peter Allebeck, Olveen Carrasquillo, Alfred L. McAlister, Kristine M. Molina, Stephen Birch, Amiram Gafni, Linda C. Baumann, Alyssa Karel, Howard Sollins, Catharina Hjortsberg, Lee Sanders, Yori Gidron, Erin N. Marcus, Olveen Carrasquillo, Vincent Tran, Peter Allebeck, Maartje Wit, Tibor Hajos, Yori Gidron, Sheah Rarback, Margaret Wallhagen, Margaret Wallhagen, Siqin Ye, Jonathan Newman, William Whang, Mark Hamer, Timothy W. Smith, Scott DeBerard, Peter A. Shapiro, Yoichi Chida, Valerie Sabol, Annie T. Ginty, Julian F. Thayer, Yoshinobu Kanda, Jonathan Newman, Carrie Brintz, Timothy Whittaker, Jennifer Wessel, Laura Rodriguez-Murillo, Rany M. Salem, Yutaka Matsuyama, J. Rick Turner, Neil Schneiderman, John Ruiz, Mariana Garza, Lauren Smith, Scott DeBerard, Nicole Overstreet, Jason W. Mitchell, Olveen Carrasquillo, Osvaldo Rodriguez, Jens Gaab, Siqin Ye, Laura Rodriguez-Murillo, Rany M. Salem, Yori Gidron, Oliver T. Wolf, Andrea Croom, Hollie B. Pellosmaa, Tamer F. Desouky, Steven C. Palmer, Kimberly M. Henderson, Susan A. Everson-Rose, Cari J. Clark, Susan A. Everson-Rose, Cari J. Clark, Kimberly M. Henderson, Susan A. Everson-Rose, Cari J. Clark, Kimberly M. Henderson, Kimberly M. Henderson, Susan A. Everson-Rose, Cari J. Clark, Jonathan Z. Bakdash, Frank A. Drews, Rany M. Salem, Laura Rodriguez-Murillo, Luis I. García, Lynnee Roane, Michael James Coons, Alyssa Parker, Kelly Flannery, Douglas Carroll, Leah Rosenberg, Molly S. Clark, Katherine T. Fortenberry, Kate L. Jansen, Alyssa Parker, Jennifer Heaney, Elliott A. Beaton, J. Rick Turner +113 moreopenaire +2 more sources