Results 161 to 170 of about 549,472 (306)

Tongue function and high-risk sleep-disordered breathing in youth: age-stratified associations and interactions in a Vietnamese cross-sectional study. [PDF]

Sleep Breath
Hoang DA, Nguyen TM, Tam DNN, Jagomägi T.   +3 more
europepmc   +1 more source

Asymptomatic Hypertrophic Cardiomyopathy: Diagnosis and Therapy [PDF]

, 2017
Fuentes, V L, Wilkie, L J
core   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Cardiac magnetic resonance assessment of left ventricular phenotypes and prognostic implications in hypertensive heart disease. [PDF]

Clin Hypertens
Lertsiripatarajit P, Wanitchung K, Prechawuttidech S, Tongsai S, Kaolawanich Y.   +4 more
europepmc   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

Animal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen, Xijia Shao, Xiulin Zhang, Ningning Zhang, Xiao Chen, Guangxin Yue, Jiangping Song   +6 more
wiley   +1 more source

Evolving Congenital Hypertrophy of the Retinal Pigment Epithelium in a Pediatric Patient. [PDF]

J Vitreoretin Dis
Pan S, Lim J, Mai D, Pirouz A, Adrean SD.   +4 more
europepmc   +1 more source

Diagnosing Right Ventricular Hypertrophy [PDF]

, 2010
Ginter, James F., Loftis, Patrick
core   +1 more source

Evaluation of quantitative muscle MRI and an intelligent phenotyping housing system as advanced phenotyping methods in a mouse model of calpain 3‐deficient muscular dystrophy

Animal Models and Experimental Medicine, EarlyView.
We applied quantitative MRI of the lower limb and automated home‐cage phenotyping to a mouse model of calpainopathy to detect early disease changes. At 15 months, calpain 3‐deficient mice showed increased water T2 values correlating with immune cell infiltration in the soleus and gastrocnemius muscles, while assessment of motor activity revealed only ...
Nicolina Südkamp, Marlena Rohm, Gabriele Russo, Xavier Helluy, Abdulhadi Kocabas, Martijn Froeling, Felix Kleefeld, Denise Manahan‐Vaughan, Tobias Ruck, Frank Jacobsen, Matthias Vorgerd, Johannes Forsting, Lara Schlaffke   +12 more
wiley   +1 more source

Interpreting a Thick Myocardium on Cardiac MR: A Practical Guide for Radiologists. [PDF]

J Korean Soc Radiol
Kim MY, Koo HJ, Chun EJ, Lee W.
europepmc   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source