Results 141 to 150 of about 674,192 (414)

Contrôle paracrine du développement du tissu adipeux par l'autotaxine et l'acide lysophosphatidique [PDF]

open access: yesarXiv, 2006
Secretion and role of autotaxin and lysophosphatidic acid in adipose tissue In obesity, adipocyte hypertrophy is often associated with recrutement of new fat cells (adipogenesis) under the control of circulating and local regulatory factors. Among the different lipids released in the extracellular compartment of adipocytes, our group found the presence
arxiv  

Inflammation-driven glial alterations in the cuprizone mouse model probed with diffusion-weighted magnetic resonance spectroscopy at 11.7 T [PDF]

open access: yesarXiv, 2020
Inflammation of brain tissue is a complex response of the immune system to the presence of toxic compounds or to cell injury, leading to a cascade of pathological processes that include glial cell activation. Noninvasive magnetic resonance imaging markers of glial reactivity would be very useful for in vivo detection and monitoring of inflammation ...
arxiv  

Pathogenesis of ventricular hypertrophy

open access: yesJournal of the American College of Cardiology, 1985
Growth of the vertebrate heart during embryonic and fetal life is characterized by hyperplasia of myocardial cells. Shortly after birth, myocardial cells lose the capability of dividing, and further growth of the heart is due to myocardial cell hypertrophy and nonmuscle cell hyperplasia.
openaire   +3 more sources

Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy

open access: yesNature Communications, 2017
Exercise induces expression of the myokine irisin, which is known to promote browning of white adipose tissue and has been shown to mediate beneficial effects following exercise. Here we show that irisin induces expression of a number of pro-myogenic and
M. M. Reza   +7 more
semanticscholar   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

open access: yesAdvanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu   +13 more
wiley   +1 more source

Prognostic value of global longitudinal strain in hypertrophic cardiomyopathy: A systematic review and meta‐analysis

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1184-1191, December 2022., 2022
Abstract Background As previously reported, impairment of left ventricular global longitudinal strain (LVGLS) is associated with myocardial fibrosis, arrhythmias, and heart failure in hypertrophic cardiomyopathy (HCM) patients. Hypothesis This study aimed to estimate the association between LVGLS measured by echocardiography and major adverse ...
Ying Yang   +3 more
wiley   +1 more source

Community level evaluation of adenoid hypertrophy on the basis of symptom scoring and its X-ray correlation

open access: yesJournal of Family Medicine and Primary Care, 2016
Introduction: One of the major causes of pediatric morbidity today at the community level is infection involving the ear, nose, and throat. Maximum of these patients respond well initially on general regular medications, but then recurrent complaints are
Yogita Dixit, Prem Siddharth Tripathi
doaj   +1 more source

Characterization of Left Ventricular Hypertrophy via Fractional Derivatives [PDF]

open access: yesarXiv, 2017
In this paper, we have used the concepts of the fractional derivative of rough curves to characterize ECG of LVH patients and compared the results with normal ECGs. In mathematical language, an ECG is a rough curve having Q, R, S points as non-differentiable points where classical derivatives do not exist but fractional derivatives exist.
arxiv  

SIRT2 Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy

open access: yesCirculation, 2017
Background: Pathological cardiac hypertrophy induced by stresses such as aging and neurohumoral activation is an independent risk factor for heart failure and is considered a target for the treatment of heart failure.
Xiaoqiang Tang   +12 more
semanticscholar   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

open access: yesAdvanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen   +12 more
wiley   +1 more source

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