Heat shock transcription factor 1 preserves cardiac angiogenesis and adaptation during pressure overload [PDF]
, 2008 To examine how heat shock transcription factor 1 (HSF1) protects against maladaptive hypertrophy during pressure overload, we subjected HSF1 transgenic (TG), knockout (KO) and wild type (WT) mice to a constriction of transverse aorta (TAC), and found ...
Aijun Sun +16 more
core +1 more source
Research Progress on Idebenone in Neurodegenerative Diseases
AGING MEDICINE, EarlyView.The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang +10 more
wiley +1 more source
Understanding longitudinal bi-ventricular structural and functional changes in a Pulmonary Hypertension Sugen-Hypoxia rat model by Cardiac Magnetic Resonance Imaging [PDF]
, 2020 Buist, Hanna +14 more
core +2 more sources
Mechanism of RNA Oxidation and Its Inhibitor Involved in Ang II‐Induced Cardiomyocyte Hypertrophy
AGING MEDICINE, EarlyView.The oxidative damage of RNA is involved in the process of cardiomyocyte hypertrophy. The mechanism may be that 8‐oxoG, a product of RNA oxidation, activates the downstream ERK‐MAPK signaling pathway. ABSTRACT Objectives To explore the mechanism of RNA oxidation and its inhibitor MTHI involved in cardiomyocyte hypertrophy.
Tong Liu, Jin Bian
wiley +1 more source
Partial liver volume radioembolization induces hypertrophy in the spared hemiliver and no major signs of portal hypertension [PDF]
, 2013 Nerea Fernández-Ros +9 more
openalex +1 more source
Annals of Gastroenterological Surgery, EarlyView.Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai +9 more
wiley +1 more source
Simvastatin inhibited cardiac hypertrophy and fibrosis in apolipoprotein E-deficient mice fed a “Western-style diet” by increasing PPAR α and γ expression and reducing TC, MMP-9, and Cat S levels [PDF]
, 2010 Yanwen Qin +5 more
openalex +1 more source