Results 61 to 70 of about 70,452 (325)

Identification of four genes as novel susceptibility loci for early‑onset type 2 diabetes mellitus, metabolic syndrome, or hyperuricemia [PDF]

, 2018
Given that early‑onset type 2 diabetes mellitus (T2DM), metabolic syndrome (MetS), and hyperuricemia have been shown to have strong genetic components, the statistical power of a genetic association study may be increased by focusing on early‑onset ...
Fujimaki Tetsuo, Horibe Hideki, Kato Kimihiko, Oguri Mitsutoshi, Sakuma Jun, Takeuchi Ichiro, Yamada Yoshiji, Yasukochi Yoshiki, 佐久間 淳   +8 more
core   +2 more sources

Exploration of molecular biomarkers in ankylosing spondylitis transcriptomics

Frontiers in Immunology
BackgroundInflammation of the spine and sacroiliac joints is a hallmark of the chronic, progressive inflammatory illness known as ankylosing spondylitis (AS). The insidious onset and non-specific early symptoms of AS often lead to delays in diagnosis and
Yuanpiao Ni, Yuanpiao Ni, Linrui Zhong, Linrui Zhong, Yanhui Li, Yanhui Li, Zeng Zhang, Zeng Zhang, Bin Ming, Bin Ming, Yufeng Qing, Yufeng Qing, Quanbo Zhang, Quanbo Zhang   +13 more
doaj   +1 more source

Gouty arthritis of the spine in a renal transplant patient : a clinical case report: an unusual presentation of a common disease [PDF]

, 2015
Axial gout is a well-documented but uncommon manifestation of gout. Its mimicking nature and the impracticality of axial joint aspiration might considerably delay its diagnosis.
Dhaese, Sofie, STRYCKERS, MARIJKE, Terryn, Wim, VAN DER MEERSCH, HANS, Van Laecke, Steven   +4 more
core   +1 more source

Association of hypertension and hypertriglyceridemia on incident hyperuricemia: an 8-year prospective cohort study

Journal of Translational Medicine, 2020
Background Hypertension and high triglyceride are two of the most important risk factors for hyperuricemia. Epidemiological records show that hypertension and dyslipidemia often coexist and may significantly increase the risk of target organ damage ...
Yuan Zhang, Miaomiao Zhang, Xiawen Yu, Fengjiang Wei, Chen Chen, Kai Zhang, Shuzhi Feng, Yaogang Wang, Wei-Dong Li   +8 more
doaj   +1 more source

Exploration of the anti-hyperuricemia effect of TongFengTangSan (TFTS) by UPLC-Q-TOF/MS-based non-targeted metabonomics

Chinese Medicine, 2023
Background TongFengTangSan (TFTS) is a commonly used Tibetan prescription for gout treatment. Previously, TFTS (CF) was confirmed to have a significant uric acid-lowering effect.
Zhichao Huang, Wugang Zhang, Qiong An, Yifan Lang, Ye Liu, Huifang Fan, Haifang Chen   +6 more
doaj   +1 more source

Plasma aldosterone concentrations elevation in hypertensive patients: the dual impact on hyperuricemia and gout

Frontiers in Endocrinology
Background Prior research has highlighted the association between uric acid (UA) and the activation of the renin-angiotensin-aldosterone system (RAAS).
Shuaiwei Song, Xintian Cai, Junli Hu, Qing Zhu, Di Shen, Huimin Ma, Yingying Zhang, Rui Ma, Pan Zhou, Wenbo Yang, Jing Hong, Delian Zhang, Nanfang Li   +12 more
semanticscholar   +1 more source

The Interaction Between Dietary Fructose and Gut Microbiota in Hyperuricemia and Gout

Frontiers in Nutrition, 2022
With the worldwide epidemics of hyperuricemia and associated gout, the diseases with purine metabolic disorders have become a serious threat to human public health.
Xin-yu Fang, Liang-wei Qi, Hailu Chen, Peng Gao, Qin Zhang, Ruixue Leng, Yin-Guang Fan, Bao-Zhu Li, Hai-Feng Pan, D. Ye   +9 more
semanticscholar   +1 more source

Disseminated cutaneous gout: a rare manifestation of a common disease [PDF]

, 2020
Disseminated cutaneous gout is a rare atypical cutaneous manifestation of gout in which widespread dermal and subcutaneous tophi develop at extra-articular body sites.
Adler, Brandon L, Crew, Ashley, DeClerck, Brittney, Guzman, Ruben, Peng, David   +4 more
core  

Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts [PDF]

, 2013
Objectives: To assess the associations between both uric acid levels and hyperuricaemia, with ischaemic heart disease and blood pressure, and to explore the potentially confounding role of body mass index. Design: Mendelian randomisation analysis, using
Benn, Marianne, Lawlor, Debbie A., Nordestgaard, Børge G., Palmer, Tom M., Smith, George Davey, Timpson, Nicholas J., Tybjærg-Hansen, Anne   +6 more
core   +1 more source

Composite Dietary Antioxidant Index Is Negatively Associated with Hyperuricemia in US Adults: An Analysis of NHANES 2007–2018

International Journal of Endocrinology, 2023
Hyperuricemia and its complications are severe risks to human health. Dietary intervention is considered an essential part of the management of hyperuricemia.
Zhenzong Lin, Haokai Chen, Qiwen Lan, Yinghan Chen, Wanzhe Liao, Xuguang Guo   +5 more
doaj   +1 more source