Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout. [PDF]
ObjectiveLesinurad (LESU) is a selective urate reabsorption inhibitor approved at 200 mg daily for use with a xanthine oxidase inhibitor (XOI) to treat hyperuricaemia in gout patients failing to achieve target serum urate on XOI. The aim of the study was
Baumgartner, Scott +8 more
core +1 more source
Testosterone replacement elevates the serum uric acid levels in patients with female to male gender identity disorder [PDF]
Gender identity disorder (GID) results from a disagreement between a person's biological sex and the gender to which he or she identifies. With respect to the treatment of female to male GID, testosterone replacement therapy (TRT) is available.
Araki, Motoo +9 more
core +1 more source
Sima Golmohammadi,1,2 Marjan Tavasoli,1 Nadia Asadi1,2 1Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Department of Internal Medicine, School of Medicine, Kermanshah University of ...
Golmohammadi S, Tavasoli M, Asadi N
doaj
Risk Factors of Left Ventricular Hypertrophy in Male Students, in Manado, North Sulawesi [PDF]
Background: Left Ventricular Hypertrophy (LVH) is an independent risk factor of heart failure. Previous study reported several cases of LVH in college‘s students, so it‘s very important to know the risk factors of LVH in young adults.
Kandou, G. (GD) +2 more
core +1 more source
Children with non‐overweight combined with metabolic risk factors might increase the risk of non‐alcoholic fatty liver disease (NAFLD). These findings suggest that overweight and obesity should not be the sole criterion for NAFLD screening in children. In particular, more attention should be given to non‐overweight combined with metabolic abnormalities
Peiyu Ye +22 more
wiley +1 more source
Probiotics in Alleviating Hyperuricemia: Research Status, Mechanism of Action and Challenges
Hyperuricemia (HUA) is a chronic metabolic disease, characterized by excessive uric acid in the blood, caused by purine metabolism disorders. Studies show that conventional clinical treatment methods have certain limitations, while probiotics have the ...
Xinru YANG +5 more
doaj +1 more source
Association between oral health and hyperuricemia in Korean adults: Korea National Health and Nutrition Examination Survey 2016–2019 [PDF]
Background/Aims Hyperuricemia plays an essential role in the gout. Despite the clinical significance of hyperuricemia, a direct relationship between oral health and hyperuricemia has not been established.
Junyong Park +4 more
doaj +1 more source
Treatment with Allopurinol is Associated with Lower Risk of Acute Kidney Injury in Patients with Gout: A Retrospective Analysis of a Nested Cohort [PDF]
Gout is characterized by recurrent episodes of acute inflammation of joint structures, called gout flares, and flares are commonly treated with nonsteroidal anti-inflammatory drugs (NSAIDs).
Pérez Ruiz, Fernando
core +2 more sources
POS0520 CARDIOVASCULAR SAFETY OF FEBUXOSTAT IN PATIENTS WITH GOUT OR HYPERURICEMIA: A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS [PDF]
R. Ghossan +4 more
openalex +1 more source
Long‐term remission in gout: Challenges and future opportunities
Prolonged hyperuricemia is a major risk factor for gout, which is now regarded as a curable disease. Awareness of the various factors that can trigger gout flares is essential for their prevention. An important determinant of treatment decisions and long‐term follow‐up is the quality of the clinician–patient relationship. The “treat‐to‐target” approach
Patapong Towiwat, Zhanguo Li
wiley +1 more source

