Results 21 to 30 of about 424 (134)

Congenital hypothyroidism and concurrent renal insufficiency in a kitten [PDF]

open access: yes, 2014
A 3-month-old male domestic short-hair kitten was presented with chronic constipation and disproportionate dwarfism. Radiographs of the long bones and spine revealed delayed epiphyseal ossification and epiphyseal dysgenesis.
De Witt, Yolanda   +3 more
core   +2 more sources

Efficacy and Safety of DNV3 (a Lymphocyte‐activation Gene 3–blocking Antibody) Combined With Toripalimab and Chemotherapy in Advanced Melanoma: An Open‐label, Single‐arm Clinical Trial

open access: yesMedComm, Volume 7, Issue 3, March 2026.
This investigator‐initiated trial demonstrates that LAG‐3/PD‐1 dual blockade (DNV3 + toripalimab) combined with chemotherapy achieves a 44.4% overall response rate (ORR) in advanced melanoma, showing particular efficacy in anti‐PD‐(L)1‐resistant patients (42.9% ORR, 7.36‐month median PFS), treatment‐naïve mucosal melanoma (50.0% ORR), and those with ...
Jing Lin   +9 more
wiley   +1 more source

Behavioural Signs and Neurological Disorders in Dogs and Cats [PDF]

open access: yes, 2016
The boundary between neurological and behavioural disorders often is not clear, and they often coexist. As a matter of fact, many neurological conditions lead to behavioural changes, which can be the only sign and the first sign complained by the owners.
Cantile, Carlo   +3 more
core  

Recurrent haemorrhage, due to vitamin K‐dependent coagulopathy, as the primary presenting complaint in a dog with naturally occurring hypoadrenocorticism

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 5‐year‐old male neutered standard poodle, presented with recurrent gingival margin haemorrhage and associated prolongations in prothrombin time and activated partial thromboplastin time, with repeatable demonstration of clinical (bleeding) and laboratory (prothrombin time, activated partial thromboplastin time) resolution with, and relapse ...
Jenny Reeve, Aiden Pang
wiley   +1 more source

Chronic Mucocutaneous Candidiasis in Autoimmune Polyendocrine Syndrome Type 1 [PDF]

open access: yes, 2018
Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is an autosomal recessive disease caused by mutations in the autoimmune regulator (AIRE) gene, characterized by the clinical triad of chronic mucocutaneous candidiasis (CMC ...
Boualem Sendid   +10 more
core   +1 more source

Acute collapse in a dog with multiple autoimmune syndromes and polymyositis complicated by suspected organophosphate/carbamate toxicity

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 6.5‐year‐old, spayed, female dog presented in acute respiratory distress. On admission, the dog exhibited dyspnoea, bradycardia, cyanosis and gastrointestinal signs, requiring immediate intubation and mechanical ventilation. Diagnostic evaluation revealed reduced butyrylcholinesterase activity, non‐cardiogenic pulmonary oedema, elevated ...
Sarah Hefer   +6 more
wiley   +1 more source

A Retrospective Study of First‐Line Immunotherapy for Advanced Non‐Small Cell Lung Cancer in the Elderly

open access: yesAGING MEDICINE, Volume 8, Issue 6, Page 592-611, December 2025.
This is a retrospective study of the efficacy and safety of first‐line immunotherapy in elderly patients with advanced NSCLC. The hematologic prognostic markers of first‐line immunotherapy in advanced NSCLC patients, especially PNI, were investigated.
Sheng Yang   +3 more
wiley   +1 more source

Canine immune-mediated disease [PDF]

open access: yes, 2018
Immune-mediated diseases in dogs constitute a large group of disorders with the common attribute that they are caused by dysfunctions in the immune system. Broadly they can be classified into immunodeficiency disorders, allergies, and autoimmune diseases.
Bremer, Hanna
core  

Koirien proteiinihukkaa aiheuttavat suolistosairaudet [PDF]

open access: yes, 2021
Kirjallisuuskatsauksen tavoitteena on selvittää, mitä tämän hetken tutkimustiedon perusteella tiedetään koirien proteiinihukkaa aiheuttavien suolistosairauksien (protein-losing enteropathies, PLE) patofysiologiasta, etiologiasta sekä mahdollisista ...
Kymäläinen, Mari
core  

Corticosteroids with low glucocorticoid activity as a potential therapeutic strategy for post‐COVID‐19 myalgic encephalomyelitis/chronic fatigue syndrome in patients with bipolar affective disorder: A case report

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Background The COVID‐19 pandemic has led to an increase in post‐acute sequelae, including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), potentially mediated by dysfunction of the hypothalamic–pituitary–adrenal (HPA) axis. Corticosteroids are occasionally administered to ameliorate fatigue symptoms in ME/CFS; however, their ...
Kan Nakajima   +8 more
wiley   +1 more source

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