Results 131 to 140 of about 12,161 (217)

Safety, Tolerability and Antiviral Activity of GST‐HG131 in Chronic Hepatitis B: A Randomized, Double‐Blind Phase IIa Study

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims Chronic hepatitis B (CHB) remains a major global health burden. Current therapies rarely achieve a functional cure due to low rates of HBsAg clearance, the persistence of the viral replication template—covalently closed circular DNA (cccDNA)—and the need for lifelong treatment.
Yuming Guo, Zhe Xu, Yuanyuan Li, John Mao, Tianxiang Zhang, Yonggang Li, Fanping Meng, Junliang Fu, Dong Ji, Yingjie Ji, Yongqian Cheng, Min Zhang, Xin Zhang, Ying Sun, Zuxiong Huang, Dachuan Cai, Wenqiang Wu, Wenhao Yan, Xiuping Yan, Guoping Li, Jinlin Hou, George Zhang, Fu‐Sheng Wang   +22 more
wiley   +1 more source

Extensive Parenchymal Brain Calcification in a Patient With Autosomal Dominant Polycystic Kidney Disease and Stage 5 Chronic Kidney Disease

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Extensive parenchymal brain calcification is uncommon in chronic kidney disease (CKD): intracranial vascular calcification affects up to 10% of uremic patients, but widespread Fahr‐type parenchymal deposits are rare and, where reported, have occurred in patients with a coexisting hypoparathyroid or parathyroid‐hormone (PTH)‐resistant state. We
Noorelle Khan, Nicholas Streicher
wiley   +1 more source

Perioperative Rhabdomyolysis Following Prolonged Laparoscopic Radical Nephrectomy in the Lateral Decubitus Position

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Perioperative rhabdomyolysis can occur after prolonged laparoscopic nephrectomy, particularly in obese patients positioned in the lateral decubitus position. In high‐risk patients undergoing prolonged surgery, early postoperative creatine kinase measurement is essential for timely diagnosis.
Madeline Dow, Aariya Srinivasan, Sabry Ayad   +2 more
wiley   +1 more source

Ethylene Glycol Poisoning Without Fomepizole in a Regional Australian Intensive Care Unit: The Lactate Gap as the Diagnostic Key and the Consequences of Nasogastric Ethanol Therapy

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 62‐year‐old man presented comatose with pH 6.88 and no ingestion history. A point‐of‐care lactate above 31 mmol/L with a laboratory lactate of 0.8 mmol/L revealed a lactate gap, diagnosing ethylene glycol poisoning despite a near‐normal osmolar gap. High‐dose continuous renal replacement therapy corrected the acidosis; he survived.
Jacob Athans, Prashant Maan
wiley   +1 more source

Acute Pancreatitis Presenting With ST‐Segment Elevation and Marked Troponin Elevation: A Diagnostic Dilemma in a Resource‐Limited Setting—A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Acute pancreatitis can present with ST‐segment elevation and marked troponin elevation, mimicking acute coronary syndrome. In resource‐limited settings where coronary angiography, cardiac magnetic resonance imaging, and serial high‐sensitivity troponin testing are unavailable, distinguishing acute myocardial injury associated with pancreatitis
Selamawit Kassahun Aweke, Natnael Mathewos Assale, Anteneh Girma Mengistu, Nathanael Elias Temesgen, Eden Fanta Amajo, Saron Yohannes Tsegaye, Merahi Kefyalew Merahi   +6 more
wiley   +1 more source

Hypocalcaemia following thyroidectomy unresponsive to oral therapy Case report

, 2020
Hypocalcaemia due to hypoparathyroidism following thyroidectomy is a relatively common occurrence. Standard treatment is with oral calcium and vitamin D replacement therapy; lack of response to oral therapy is rare.
Christopher Schofield, Zac C Etheridge, Peter J J Prinsloo, Zac C Etheridge Bsc, BMBCh, DPhil, MRCP Hons, Nigel D C Sturrock   +5 more
core  

Recurrent Projectile Vomiting as the Sole Presenting Feature of Coeliac Disease With Marsh–Oberhuber Grade 3C Enteropathy in a 13‐Year‐Old Girl: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 13‐year‐old girl presented with 4 months of recurrent projectile vomiting and weight loss without diarrhea. Investigations confirmed hypochloraemic metabolic alkalosis, strongly positive coeliac serology, nutritional deficiency, and biopsy‐proven Marsh–Oberhuber Grade 3C total villous atrophy.
Rahman Syed, Ameer Afzal Khan, Mehtab Alam, Suleman Shah, Mian Gul Rahman, Mohammed Al Meqbaali, Bilal Iqbal, Mohammed Al Sinani   +7 more
wiley   +1 more source

Single‐Nucleotide Polymorphisms in Calcium and Vitamin D Maintenance Genes Association With Tooth Size

Clinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.
ABSTRACT Objectives This study investigated the association between Single Nucleotide Polymorphisms (SNPs) in calcium and vitamin D maintenance genes and mesiodistal tooth size (MTS) of permanent teeth. Materials and Methods A total of 108 patients undergoing orthodontic treatment were recruited.
Lucas Cabral Rodrigues, Mirian Aiko Nakane Matsumoto, Maria Bernadete Sasso Stuani, Guido Artemio Marañón‐Vásquez, Fábio Lourenço Romano, Daniela Silva Barroso de Oliveira, Juliane Cora da Silva, Flares Baratto‐Filho, Christian Kirschneck, Erika Calvano Küchler, Caio Luiz Bitencourt Reis   +10 more
wiley   +1 more source

Spontaneous Tumour Lysis Syndrome in Metastatic Endometrial Carcinoma. [PDF]

Cureus
Coggins K, Irving A.
europepmc   +1 more source

Bilateral detection, prediction, and lateralization of seizures using white matter

Epilepsia Open, Volume 11, Issue 5, Page 1825-1840, October 2026.
Abstract Objective To determine how the corpus callosum handles interhemispheric seizure propagation and to assess its potential as a strategic recording locus for state‐dependent biomarkers. Methods Epileptiform activity was induced in vitro and in vivo using 4‐aminopyridine. Propagation dynamics were examined using cross‐correlation analysis.
Nrupen Pakalapati, Chia‐Chu Chiang, Siddharth Lokam, Dominique M. Durand   +3 more
wiley   +1 more source