Results 11 to 20 of about 15,844 (277)

Denosumab-Induced Severe Hypocalcaemia in Chronic Kidney Disease

Case Reports in Nephrology, 2018
Background. Hypocalcaemia is increasingly recognized as a complication of denosumab use in Chronic Kidney Disease (CKD) patients with osteoporosis. Despite Therapeutic Goods Administration (TGA) notifications in 2013, we have subsequently encountered ...
Ryan Jalleh, Gopal Basu, Richard Le Leu, Shilpanjali Jesudason   +3 more
doaj   +2 more sources

HYPOCALCAEMIA – CASE REPORT

Slovenska pediatrija, 2022
Hypocalcaemia is a common disorder of calcium and phosphate metabolism in children, especially in newborns. It is often asymptomatic; clinical signs and symptoms are dependent on the age of the child.
Tina Svetlik, Klemen Dovč, Primož Kotnik   +2 more
doaj   +2 more sources

Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis [PDF]

Journal of Pharmaceutical Health Care and Sciences
Background We examined whether denosumab-induced hypocalcaemia is evident in osteoporosis when given loop diuretics that promote urinary calcium excretion.
Toshinori Hirai, Yukari Mori, Toru Ogura, Yuki Kondo, Yuka Sakazaki, Yoichi Ishitsuka, Akihiro Sudo, Takuya Iwamoto   +7 more
doaj   +2 more sources

Determination of risk factors causing hypocalcaemia after thyroid surgery

Asian Journal of Surgery, 2019
Summary: Objective: The most common complication after thyroid surgery is hypocalcaemia and it sometimes leads to problems that are difficult to correct in patients.
Azmi Lale, Abdullah Bahadır Öz, Alper Celal Akcan, Erdoğan Mütevelli Sözüer, Türkmen Bahadır Arıkan, Mustafa Gök   +5 more
doaj   +2 more sources

Hypocalcaemia in patients with prostate cancer treated with a bisphosphonate or denosumab: prevention supports treatment completion

BMC Urology, 2018
Background Most patients with advanced prostate cancer develop bone metastases, which often result in painful and debilitating skeletal-related events. Inhibitors of bone resorption, such as bisphosphonates and denosumab, can each reduce the incidence of
Jean-Jacques Body, Roger von Moos, Daniela Niepel, Bertrand Tombal   +3 more
doaj   +2 more sources

Chronic kidney disease and denosumab in metastatic bone disease: A multicenter Turkish cohort study on severe hypocalcemia, skeletal events, and survival [PDF]

Journal of Bone Oncology
Background: Denosumab, a monoclonal antibody against receptor activator of nuclear factor kappa-B ligand (RANKL), is widely used to prevent skeletal-related events (SREs) in patients with bone metastases from solid tumours.
Halil İbrahim Ellez, Hüseyin Salih Semiz, Ferhat Ekinci, Atike Pınar Erdoğan, Fatih Kuş, Fatih Karataş, Ertuğrul Bayram, Kubilay Karaboyun, Havva Yeşil Çınkır, Nilgün Yıldırım, Melek Karakurt Eryılmaz, Esma Türkmen Bekmez, Özkan Alan, Melike Özçelik, Yakup Düzköprü, Teoman Şakalar, Naziye Ak, Yusuf İlhan, Tuğba Yavuzşen, Nazım Serdar Turhal   +19 more
doaj   +2 more sources

Acute severe hypocalcaemia after initiation of a selective RET-inhibitor in medullary thyroid cancer [PDF]

Endocrine Oncology
Medullary thyroid cancer (MTC) is a rare subtype of thyroid cancer originating from parafollicular C-cells of the thyroid. Tyrosine kinase inhibitors are used to treat patients with advanced MTC.
Leslie Cheng, Syeda Khadijah Ghaznavi, Jessica Stevens, Sonja Hoy, Kee Howe Wong, Tass Malik, Kate Newbold, Daniel Morganstein   +7 more
doaj   +2 more sources

Hypercalcaemia and hypocalcaemia: finding the balance

Supportive Care in Cancer, 2017
Calcium metabolism in cancer and hypercalcaemia of malignancyThe balance between bone formation and resorption may be disrupted in patients with cancer, leading either to increased bone resorption, calcium release, and possibly hypercalcaemia, or to ...
Jean-Jacques Body, Giuseppe Tonini
exaly   +2 more sources

Prevalence of hypocalcemia in asymptomatic pregnant females in Upper Egypt [PDF]

Egyptian Journal of Medical Research, 2022
The goal of this study is to investigate the levels of serum calcium in asymptomatic pregnant women and measuring the prevalence of hypocalcaemia. Healthy pregnant women (n=500) were enrolled consecutively, with singleton pregnancy, in first trimester ...
Asmaa Abdel Aty, Mohamed Youssef, Yasser Mohamed   +2 more
doaj   +1 more source

Management of hypocalcaemia in the critically ill

Current Opinion in Critical Care, 2023
Purpose of review To better understand the established associations between hypocalcaemia and clinical outcomes, we synopsize the mechanisms involved in hypocalcaemia in the critically ill.
Max Melchers, A. V. van Zanten
semanticscholar   +1 more source